Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Thomas G. Rosano"'
Autor:
Thomas G. Rosano, Michelle Wood, Kiley L. Scholz, Kiera Whitely, Nathaniel Kim, Melissa Ehlers
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 32, Iss , Pp 60-67 (2024)
Introduction: Chromatographic methods for analysis of propofol and its metabolites have been widely used in pharmacokinetic studies of propofol distribution, metabolism, and clearance. Application of chromatographic methods is also needed in clinical
Externí odkaz:
https://doaj.org/article/35e3550908184e9fb43b90e85146d555
Autor:
Christian C.K. Kim, MD, Thomas G. Rosano, PhD, Erin E. Chambers, PhD, Manjunath P. Pai, PharmD, James Desemone, MD
Publikováno v:
AACE Clinical Case Reports, Vol 2, Iss 2, Pp e122-e128 (2016)
ABSTRACT: Objective: Insulin glargine is a long-acting insulin analogue with biotransformation, at the injection site, to a primary active metabolite (glargine-M1). Combined therapy with rapid-acting insulin aspart is common, but pharmacokinetics wit
Externí odkaz:
https://doaj.org/article/b82c4011e1d84e138995bd21bb47a278
Autor:
Michelle Wood, W. Michael Hooten, Thomas G. Rosano, Charles Argoff, John M Rumberger, Jeffrey Fudin
Publikováno v:
Pain Medicine. 23:821-833
Objective To assess routine application and clinical value of definitive urine drug monitoring (UDM) for drug detection, inconsistent drug use, and prescription adherence, along with a comparison to immunoassay screening (IAS). Methods Direct-to-defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7fa0cfe93413b921e6cd2f01b99d50
https://doi.org/10.1093/pm/pnab303
https://doi.org/10.1093/pm/pnab303
Publikováno v:
Clin Mass Spectrom
The opioid crisis is linked to an increased misuse of fentanyl as well as fentanyl analogs that originate from the illicit drug market. Much of our current understanding of fentanyl and fentanyl analog use in our communities comes from postmortem tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e391f55d88ba91c5c20921c1fb5f027
https://doi.org/10.1016/j.clinms.2020.10.003
https://doi.org/10.1016/j.clinms.2020.10.003
Publikováno v:
Journal of analytical toxicology. 45(8)
Analytical performance of stable isotope-labeled internal standardization (SIL-IS) and threshold accurate calibration (TAC) methods of matrix normalization are compared for quantitation of 51 drugs and metabolites (analytes) in urine with analysis by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaeb253c56c3afe82b2748849c8c8d8
https://pubmed.ncbi.nlm.nih.gov/34013336
https://pubmed.ncbi.nlm.nih.gov/34013336
Publikováno v:
Journal of Studies on Alcohol and Drugs. 78:945-948
Even moderate alcohol consumption during pregnancy can pose risks to the fetus, making reliable and consistent detection of drinking in pregnancy critical. Ethyl glucuronide (EtG) and ethyl sulfate (EtS) have shown some ability to detect lower levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7980e6bd97908c09cff4527e7b31de63
https://doi.org/10.15288/jsad.2017.78.945
https://doi.org/10.15288/jsad.2017.78.945
Publikováno v:
Journal of Analytical Toxicology. 40:628-638
Drug screening is an essential analytical tool for detection of therapeutic, illicit and emerging drug use. Presumptive immunoassay screening is widely used, while initial definitive testing by chromatography-coupled mass spectrometry is hampered due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8790c780e02a9fd33853b81a1630721
https://doi.org/10.1093/jat/bkw050
https://doi.org/10.1093/jat/bkw050
Publikováno v:
Journal of analytical toxicology. 43(5)
The transition from presumptive (immunoassay) drug screening to definitive screening has continued in the practice of analytical toxicology. Development of a ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) screening meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d18a595c9a7bcd11b0c51cca86ef2fd
https://pubmed.ncbi.nlm.nih.gov/30753546
https://pubmed.ncbi.nlm.nih.gov/30753546
Publikováno v:
Journal of analytical toxicology. 41(6)
Drug and metabolite (analytes) identification together with quantification is an important analytical tool in forensic and clinical toxicology. We report the development and validation of a definitive detection and quantification method (UPLC-MS-MS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9694815e89763140fb71d80d8deaab
https://pubmed.ncbi.nlm.nih.gov/28541461
https://pubmed.ncbi.nlm.nih.gov/28541461
Autor:
David C. Spink, Alex J. Rai, Zhimin Tim Cao, Erasmus Schneider, Baorong Chen, Helen Ling, Xianzhang Huang, Thomas G. Rosano
Publikováno v:
Clinical Chemistry. 60:260-268
BACKGROUNDUnconjugated estriol (uE3) is routinely analyzed in clinical laboratories as risk assessment for Down syndrome. Immunoassays of various types are the most commonly used methods. The accuracies of RIAs and ELISAs for uE3 have been questioned
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6762ac19e1b86dfa409a4c15378319
https://doi.org/10.1373/clinchem.2013.212126
https://doi.org/10.1373/clinchem.2013.212126