Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Thomas G. Baboolal"'
Publikováno v:
Royal Society Open Science, Vol 3, Iss 3 (2016)
Aggrecan, a highly charged macromolecule found in articular cartilage, was investigated in aqueous salt solutions with proton nuclear magnetic resonance. The longitudinal and transverse relaxation rates were determined at two different field strength
Externí odkaz:
https://doaj.org/article/6f2f433765744d6d99102a05ea4b4db1
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3371, p 3371 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3371, p 3371 (2020)
Actin is a widely expressed protein found in almost all eukaryotic cells. In humans, there are six different genes, which encode specific actin isoforms. Disease-causing mutations have been described for each of these, most of which are missense. Ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bda87d13590ce652793dbe3d71e1f6
https://eprints.whiterose.ac.uk/160453/8/ijms-21-03371.pdf
https://eprints.whiterose.ac.uk/160453/8/ijms-21-03371.pdf
Autor:
Owen Wall, Anthony A Theodorides, Elena Jones, Thomas G. Baboolal, Dennis McGonagle, Alam Khalil-Khan
Publikováno v:
The American Journal of Sports Medicine
Background: Mesenchymal stem cells (MSCs) have emerged as a promising candidate for tissue regeneration and restoration of intra-articular structures such as cartilage, ligaments, and menisci. However, the routine use of MSCs is limited in part by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a895f9e69c15bcc76e1f8a7db4bd4a7
http://europepmc.org/articles/PMC6282154
http://europepmc.org/articles/PMC6282154
Publikováno v:
The Journal of Knee Surgery. 32:788-795
Knee joint distraction (KJD) is a new application of an established technique to regenerate native cartilage using an external fixator. The purpose of this study is to perform a systematic review and meta-analysis of the literature to determine wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d9e90ccf13e89a8cf016024ff8ca80
https://doi.org/10.1055/s-0038-1669447
https://doi.org/10.1055/s-0038-1669447
Publikováno v:
Nature Reviews Rheumatology. 13:719-730
The role of native (not culture-expanded) joint-resident mesenchymal stem cells (MSCs) in the repair of joint damage in osteoarthritis (OA) is poorly understood. MSCs differ from bone marrow-residing haematopoietic stem cells in that they are present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f714d7dd193efe8d4f2289ca56887c68
https://doi.org/10.1038/nrrheum.2017.182
https://doi.org/10.1038/nrrheum.2017.182
Autor:
Thomas G. Baboolal, Jehan J. El-Jawhari, Dennis McGonagle, Clara Sanjurjo-Rodríguez, Elena Jones, Agata Burska, Hemant Pandit, Frederique Ponchel
Publikováno v:
RUC. Repositorio da Universidade da Coruña
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
instname
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Osteoarthritis (OA) is the most common degenerative joint disorder. Multipotential stromal cells (MSCs) have a crucial role in joint repair, but how OA severity affects their characteristics remains unknown. Knee OA provides a good model to study thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90cda5ec8e5c7faafd3147d62aa8d7f
https://doi.org/10.1038/s41598-019-45820-w
https://doi.org/10.1038/s41598-019-45820-w
Autor:
Clara Sanjurjo Rodriguez, Hemant Pandit, Jehan J. El-Jawhari, Agata Burska, Dennis McGonagle, Elena Jones, Joseph Aderinto, Frederique Ponchel, Owen Wall, Thomas G. Baboolal
Publikováno v:
Abstracts Accepted for Publication.
Background Osteoarthritis (OA) is the most common degenerative joint disorder, mainly afflicting the weight–bearing joints, and is the leading cause of physical disability worldwide. Despite the identified risk factors, the exact pathogenesis of os
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be3c5d04b20a9f49c5c85f8ab9b42094
https://doi.org/10.1136/annrheumdis-2019-eular.2649
https://doi.org/10.1136/annrheumdis-2019-eular.2649
Autor:
Richard Cuthbert, Thomas G. Baboolal, Elena Jones, Almas Khan, Peter Millner, Robert Dunsmuir, Abdulla Watad, Abhay Rao, Dennis McGonagle, Charlie Bridgewood, Tobias Russell, Peter Loughenbury
Publikováno v:
Cartilage, synovium and bone.
Background Ankylosing spondylitis (AS) is associated with entheseal inflammation and new bone formation. Resident populations of lymphocytes have been identified at the enthesis that on stimulation with IL-23 produce pro-inflammatory cytokines includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b05a12cf20b9cdfdca3f049f632697c
https://doi.org/10.1136/annrheumdis-2019-eular.2638
https://doi.org/10.1136/annrheumdis-2019-eular.2638
Autor:
Thomas G. Baboolal, Justin E. Molloy, Tatiana A. Nenasheva, Gregory I. Mashanov, Michelle Peckham
Publikováno v:
The Journal of Biological Chemistry
Myosin 10 is an actin-based molecular motor that localizes to the tips of filopodia in mammalian cells. To understand how it is targeted to this distinct region of the cell, we have used total internal reflection fluorescence microscopy to study the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a9bb9ba82ef3696247014edd9c4f6d
https://doi.org/10.1074/jbc.m116.730689
https://doi.org/10.1074/jbc.m116.730689
Autor:
Thomas G. Baboolal, Sarah M Churchman, Elena Jones, Peter V. Giannoudis, Dennis McGonagle, Joseph Aderinto, Dragos C Ilas
Publikováno v:
Rheumatology (Oxford, England)
Objective OA subchondral bone is a key target for therapy development. Osteocytes, the most abundant bone cell, critically regulate bone formation and resorption. Their progenitors, mesenchymal stem cells (MSCs), display altered behaviour in osteoart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dbb9a313f14f435bc88d38f7a5e709
https://pubmed.ncbi.nlm.nih.gov/31165896
https://pubmed.ncbi.nlm.nih.gov/31165896