Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Thomas G. Aigner"'
Publikováno v:
Proceedings of the National Academy of Sciences. 98:4196-4201
Visual habit formation in monkeys, assessed by concurrent visual discrimination learning with 24-h intertrial intervals (ITI), was found earlier to be impaired by removal of the inferior temporal visual area (TE) but not by removal of either the medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd5ee74522ceeaa08ca86707c7b7301
https://doi.org/10.1073/pnas.061022098
https://doi.org/10.1073/pnas.061022098
Publikováno v:
Psychopharmacology. 147:104-107
Rationale: The ameliorative effects of levodopa (l-3,4-dihydroxy-phenylalanine) on the motor impairment in Parkinson’s disease patients is well established, but characterization of its effects on the associated cognitive deficits is still incomplet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba3be47fadb0f22b64a33f305b05788
https://doi.org/10.1007/s002130051148
https://doi.org/10.1007/s002130051148
Publikováno v:
Brain Research. 806:292-296
Opiate receptor avidity, roughly equivalent to the ratio of unoccupied receptor density to the receptor dissociation constant (B′max/KD), was measured in four MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-lesioned rhesus monkeys and nine norm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451a71d3671056dab32ba6b4d1ca8a69
https://doi.org/10.1016/s0006-8993(98)00777-x
https://doi.org/10.1016/s0006-8993(98)00777-x
Autor:
Thomas G. Aigner, Nobuya Matsuoka
Publikováno v:
NeuroReport. 7:565-568
Administration of either a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801 (dizocilpine), or a muscarinic antagonist, scopolamine, produces dose-related impairments in performance of a visual recognition memory task, delayed n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93199e146cf91f3085eb36a0eba7ca6d
https://doi.org/10.1097/00001756-199601310-00045
https://doi.org/10.1097/00001756-199601310-00045
Publikováno v:
Psychiatry Research: Neuroimaging. 45:153-168
Positron emission tomography (PET) was carried out, with 18 F-DOPA as a ligand, in normal control monkeys and “parkinsonian” monkeys who had been treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. The following approaches were used in dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe17fecab936b8fb35bb31545d33428
https://doi.org/10.1016/0925-4927(92)90023-w
https://doi.org/10.1016/0925-4927(92)90023-w
Autor:
H. Miyake, Doris J. Doudet, Thomas G. Aigner, Robert M. Cohen, R. T. Finn, Catherine McLellan, Richard E. Carson, H. R. Adams
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 11:726-734
Most attempts to model accurately [18F]-DOPA imaging of the dopamine system are based on the assumptions that its main peripheral metabolite, 3-O-methyl-6-[18F]fluoro-L-DOPA ([18F]3-OM-DOPA), crosses the blood-brain barrier but is present as a homoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f37c503e599ecbda006347f146bf06
https://doi.org/10.1038/jcbfm.1991.129
https://doi.org/10.1038/jcbfm.1991.129
Publikováno v:
Behavioral and Neural Biology. 55:61-67
The effect of scopolamine on visual recognition memory in rhesus monkeys was assessed with a delayed nonmatching-to-sample task employing trial-unique stimuli. During the acquisition phase, 40 sample stimuli were presented sequentially. During the te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc842fb3cc66b71911cb0e88636258a
https://doi.org/10.1016/0163-1047(91)80127-z
https://doi.org/10.1016/0163-1047(91)80127-z
Autor:
Thomas G. Aigner, Richard C. Saunders, Jin Wang, Krzysztof S. Bankiewicz, Steven Skirboll, John K. Hsiao
Publikováno v:
Experimental Neurology. 110:181-186
In vivo biochemical microdialysis in primate brain would greatly expand our understanding of functional neuronal systems. This work describes our efforts to establish a microdialysis system in primate brain. Seven anesthetized rhesus monkeys underwen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d36ce4dbb8f69a324a636f2863c73f6
https://doi.org/10.1016/0014-4886(90)90028-q
https://doi.org/10.1016/0014-4886(90)90028-q
Publikováno v:
NeuroReport. 7:102-104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c8ad92716d8be0d464096f245d6f50c
https://doi.org/10.1097/00001756-199512290-00024
https://doi.org/10.1097/00001756-199512290-00024
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 18(7)
Single neurons in the ventral striatum of primates carry signals that are related to reward and motivation. When monkeys performed a task requiring one to three bar release trials to be completed successfully before a reward was given, they seemed mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dda744adad006b9f7f4ba210b143d4d
https://pubmed.ncbi.nlm.nih.gov/9502820
https://pubmed.ncbi.nlm.nih.gov/9502820