Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thomas G Warren"'
Autor:
Lydia Swenton, Stevan W. Djuric, Thomas D. Penning, Thomas G. Warren, Renee M. Huff, Gwen G. Krivi, D Villani-Price, James F. Kachur, Michael Clare, E.Yvonne Pyla
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1367-1370
The synthesis of a series of novel Leukotriene A 4 analogs containing the oxabicycloheptene nucleus has been achieved. These compounds have been evaluated as inhibitors of the Leukotriene A 4 hydrolase enzyme.
Autor:
Tze-Chein Wun, Kuniko K Kretzmer, Mark O Palmier, Kathleen C Day, Margaret D Huang, Dean J Welsch, Charles Lewis, Richard A Wolfe, James F Zobel, Gary W Lange, Ronald B Frazier, Gary S Bild, Michelle A Peel, Robert E Shell, Nancy A Horn, Kurt D Junger, Barbara A Foy, Mark E Gustafson, Richard M Leimgruber, William F Novotny, George J Broze, Yvonne E Pyla, Paul J Hippenmeyer, Thomas G Warren
Publikováno v:
Thrombosis and Haemostasis. 68:054-059
SummaryRecombinant tissue factor pathway inhibitor (rTFPI) has been expressed in four mammalian expression systems using human SK hepatoma, mouse C127, baby hamster kidney (BHK), and Chinese hamster ovary (CHO) cells as hosts. On sodium dodecyl sulfa
Autor:
Linda C. Hoffman, Kathleen C. Day, George J. Broze, Mark O. Palmier, Margaret D. Huang, Kretzmer Kuniko Kusano, Thomas G. Warren, Tze-Chein Wun, Eric Spokas, Evelyn Y. Pyla
Publikováno v:
Blood. 76:1538-1545
Lipoprotein-associated coagulation inhibitor produces feed-back inhibition of tissue factor (tissue thromboplastin)-induced coagulation in the presence of factor Xa Recombinant lipoprotein-associated coagulation inhibitor (rLACI) was tested for its a
Publikováno v:
Insect Biochemistry. 17:1187-1192
Two methods for the purification of vitellogenin from Drosophila melanogaster are described. The first method is a bulk purification starting with approximately 500 g of adult flies reared in population cages. Dimethylformamide and ammonium sulfate f
Autor:
Dennis Shields, Thomas G. Warren
Publikováno v:
Cell. 39:547-555
Somatostatin is a 14 amino acid peptide hormone that is synthesized as part of a larger precursor, preprosomatostatin, which comprises about 120 amino acids. The overall organization of the precursor is conserved in many species in that it consists o
Publikováno v:
Nature. 289:511-514
Glucagon, a polypeptide hormone of 29 amino acids, is synthesized in the islets of Langerhans and immunoreactive forms of the molecule have been found in several tissues. Like many other polypeptide hormones, glucagon is synthesized via a larger prec
Autor:
Anthony P. Mahowald, Thomas G. Warren
Publikováno v:
Developmental Biology. 68:130-139
The three major yolk polypeptides of Drosophila melanogaster have been isolated from yolk spheres of early embryos. Their molecular weights, as determined by SDS-polyacrylamide electrophoresis, are 44,000, 45,000, and 46,000. A number of approaches h
Publikováno v:
The Journal of Cell Biology
Translation of poly(A)-containing RNA from the female fat body of Drosophila melanogaster in a rabbit reticulocyte cell-free system results in the synthesis of previtellogenin polypeptides (PVs) having higher apparent molecular weights (46,000 and 45
Cell-free biosynthesis of somatostatin precursors: Evidence for multiple forms of preprosomatostatin
Autor:
Dennis Shields, Thomas G. Warren
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 79(12)
It has been demonstrated [Shields, D. (1980) J. Biol. Chem. 255, 11625-11628] that mRNA isolated from the islets of Langerhans codes for two preposomatostatin molecules of apparent molecular weights 18,000 and 19,000, respectively. Here evidence is p
Autor:
Dennis Shields, Thomas G. Warren
Publikováno v:
Biochemistry. 23(12)
In vitro translation of mRNA isolated from islets of Langerhans results in the synthesis of three major preprosomatostatins of Mr 19 000, 18 000, and 16 000, each of which can be resolved into several isoelectric forms [Warren, T. G., & Shields, D. (