Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Thomas G Oliver"'
Autor:
Elaine D, Por, Daniel J, Selig, Geoffrey C, Chin, Jesse P, DeLuca, Thomas G, Oliver, Jeffrey R, Livezey
Publikováno v:
Military Medicine. 187:1-8
Pharmacogenomics (PGx) plays a fundamental role in personalized medicine, providing an evidence-based treatment approach centered on the relationship between genomic variations and their effect on drug metabolism. Cytochrome P450 (CYP450) enzymes are
Publikováno v:
Military Medicine. 187:25-31
Introduction Providing patient-specific clinical care is an expanding focus for medical professionals and researchers, more commonly referred to as personalized or precision medicine. The goal of using a patient-centric approach is to provide safer c
Autor:
William F. McCarthy, Donna Tosh, Kristopher M Paolino, Meshell N Morrison, James E Moon, Sean R Marcsisin, Jason W. Bennett, Christian A Darko, Qigui Li, Patrick Twomey, Philip L Smith, Brittney M Potter, Gregory A Reichard, Susan B Cicatelli, Brandon S Pybus, Kristin T Mills, Jeffrey W Froude, Thomas G Oliver, Michele D. Spring, Norman C. Waters, Jason C Sousa
Publikováno v:
The Journal of Infectious Diseases
BackgroundPlasmodium vivax malaria requires a 2-week course of primaquine (PQ) for radical cure. Evidence suggests that the hepatic isoenzyme cytochrome P450 2D6 (CYP2D6) is the key enzyme required to convert PQ into its active metabolite.MethodsCYP2
Autor:
Jason W Bennett, Gregory A Reichard, Philip L Smith, Norman C Waters, William F Mccarthy, Thomas G Oliver, Brandon S Pybus, Jeffrey W Froude, Susan B Cicatelli, Donna M Tosh, James E Moon, Patrick S Twomey, Kristopher M Paolino, Brittney M Potter, Kristin T Mills, Sean R Marcsisin, Meshell N Morrison, Christian A Darko, Qigui Li, Jason C Sousa, Michele D Spring
Publikováno v:
The Journal of Infectious Diseases
Plasmodium vivax malaria requires a 2-week course of primaquine (PQ) for radical cure. Evidence suggests that the hepatic isoenzyme cytochrome P450 2D6 (CYP2D6) is the key enzyme required to convert PQ into its active metabolite.CYP2D6 genotypes and