Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Thomas G, Nührenberg"'
Autor:
Thomas G Nührenberg, Jasmin Stöckle, Federico Marini, Mark Zurek, Björn A Grüning, Vladimir Benes, Lutz Hein, Franz-Josef Neumann, Christian Stratz, Marco Cederqvist, Willibald Hochholzer
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0260222 (2022)
BackgroundSepsis is associated with high platelet turnover and elevated levels of immature platelets. Changes in the platelet transcriptome and the specific impact of immature platelets on the platelet transcriptome remain unclear. Thus, this study s
Externí odkaz:
https://doaj.org/article/412c81b9eb1f449180b7f6b5c9cd35d6
Autor:
Ralf Gilsbach, Martin Schwaderer, Sebastian Preissl, Björn A. Grüning, David Kranzhöfer, Pedro Schneider, Thomas G. Nührenberg, Sonia Mulero-Navarro, Dieter Weichenhan, Christian Braun, Martina Dreßen, Adam R. Jacobs, Harald Lahm, Torsten Doenst, Rolf Backofen, Markus Krane, Bruce D. Gelb, Lutz Hein
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
How the cardiac myocyte epigenome is rearranged during development, postnatal maturation and disease is not well understood. Here, the authors investigate the human cardiac myocyte epigenome during development and chronic heart failure and identify d
Externí odkaz:
https://doaj.org/article/e46b79bc29434dea9a7d59690c85ee94
Autor:
Stephan Nothjunge, Thomas G. Nührenberg, Björn A. Grüning, Stefanie A. Doppler, Sebastian Preissl, Martin Schwaderer, Carolin Rommel, Markus Krane, Lutz Hein, Ralf Gilsbach
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Chromatin is organized in higher order A and B compartments, reflecting active and inactive chromatin. Here, the authors provide evidence that in cardiac myocytes DNA methylation is established in preformed chromatin compartments and may be dispensab
Externí odkaz:
https://doaj.org/article/8b3e486861b4468d9a0816e1f96f830b
Autor:
Alexander Kille, Kilian Franke, Noé Corpataux, Julia Hromek, Christian M. Valina, Franz-Josef Neumann, Dietmar Trenk, Thomas G. Nührenberg, Willibald Hochholzer
Publikováno v:
Kille, Alexander; Franke, Kilian; Corpataux, Noé; Hromek, Julia; Valina, Christian M; Neumann, Franz-Josef; Trenk, Dietmar; Nührenberg, Thomas G; Hochholzer, Willibald (2022). Impact of On-Clopidogrel Platelet Reactivity on Incidence of Peri-Interventional Bleeding in Patients Undergoing Transcatheter Aortic Valve Implantation. Journal of clinical medicine, 11(10) MDPI 10.3390/jcm11102871
Journal of Clinical Medicine; Volume 11; Issue 10; Pages: 2871
Journal of Clinical Medicine; Volume 11; Issue 10; Pages: 2871
Dual anti-platelet therapy (DAPT) with clopidogrel and acetylsalicylic acid (ASA) has previously been recommended after transcatheter aortic valve implantation (TAVI) and is still the standard of care in patients who underwent coronary stent placemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de84fada741ea84749bf1f7f3393b787
https://boris.unibe.ch/170323/1/jcm-11-02871-v2.pdf
https://boris.unibe.ch/170323/1/jcm-11-02871-v2.pdf
Autor:
David K Kranzhöfer, Ralf Gilsbach, Björn A Grüning, Rolf Backofen, Thomas G Nührenberg, Lutz Hein
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166575 (2016)
Cardiomyocytes undergo major changes in DNA methylation during maturation and transition to a non-proliferative state after birth. 5'-hydroxylation of methylated cytosines (5hmC) is not only involved in DNA loss of CpG methylation but is also thought
Externí odkaz:
https://doaj.org/article/40b536f07ff944f1a313b193bb66d2fa
Autor:
Julinda Mehilli, Franz-Josef Neumann, Ingo Ahrens, Dirk Sibbing, Thomas G. Nührenberg, Willibald Hochholzer, Helge Möllmann, Tobias Geisler, Ali El-Armouche, Daniel Dürschmied, Andreas Schäfer, Marcus Dörr, Ulf Landmesser, Uwe Zeymer, Christoph B. Olivier, Ulrike Flierl
Publikováno v:
Der Kardiologe. 15:57-70
In den letzten Jahren finden strukturelle kardiale Interventionen zunehmend Anwendung in der klinischen Routine. Trotz der raschen Einfuhrung und Weiterentwicklung dieser Techniken, ist die Evidenz fur die optimale antithrombotische Therapie nach sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5bdcc0448f877162f367f28c6a5832
https://doi.org/10.1007/s12181-020-00441-w
https://doi.org/10.1007/s12181-020-00441-w
Autor:
Karlheinz Bürgelin, Ulrich Beschorner, Franz-Josef Neumann, Thomas G. Nührenberg, Florian Cheung, Tanja Böhme, Roland Macharzina, Börries Jacques, Thomas Zeller, Elias Noory
Publikováno v:
Catheterization and Cardiovascular Interventions. 96:1306-1314
OBJECTIVES To evaluate the long-term mortality after paclitaxel-coated drug-eluting stent (DES) angioplasty and use of uncoated devices of femoropopliteal lesions in real world practice. BACKGROUND A meta-analysis of randomized controlled trials repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0dbe3f30f7d6fcda7517788ea9586dc
https://doi.org/10.1002/ccd.29267
https://doi.org/10.1002/ccd.29267
Autor:
Tanja Böhme, Florian Cheung, Thomas Zeller, Ulrich Beschorner, Roland Macharzina, Ellen Gebauer, Börries Jacques, Karlheinz Bürgelin, Elias Noory, Peter Lechner, Thomas G. Nührenberg
Publikováno v:
Jacc. Cardiovascular Interventions
This study sought to evaluate the long-term mortality after paclitaxel drug-coated balloon (DCB) angioplasty and plain old balloon angioplasty (POBA) of femoropopliteal lesions in real-world practice.A recent meta-analysis of randomized controlled tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6406401a4a2883a5f4a209a9b32e4cdc
https://doi.org/10.1016/j.jcin.2020.04.050
https://doi.org/10.1016/j.jcin.2020.04.050
Autor:
Lutz Hein, Andreas Vlachos, Björn Grüning, Laura Hille, Dietmar Trenk, Thomas G. Nührenberg, Franz-Josef Neumann, Maximilian Lenz
Publikováno v:
Journal of Thrombosis and Haemostasis. 18:2034-2046
BACKGROUND Reticulated platelets (RP) are the youngest circulating platelets in blood. An increased amount of this subpopulation is associated with higher cardiovascular risk and mortality. OBJECTIVES It is unknown to what extent intrinsic properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774b48eccc31d639cb44151d88b5dd3e
https://doi.org/10.1111/jth.14895
https://doi.org/10.1111/jth.14895
Autor:
Thomas G Nührenberg, Nils Hammann, Tilman Schnick, Sebastian Preißl, Anika Witten, Monika Stoll, Ralf Gilsbach, Franz-Josef Neumann, Lutz Hein
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131019 (2015)
Recent studies reported altered DNA methylation in failing human hearts. This may suggest a role for de novo DNA methylation in the development of heart failure. Here, we tested whether cardiomyocyte-specific loss of de novo DNA methyltransferases Dn
Externí odkaz:
https://doaj.org/article/6c9c189658ab4c4e885c5b95ecc92ae1