Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Thomas G, Berger"'
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6645 (2009)
Immature dendritic cells (DC) represent potential clinical tools for tolerogenic cellular immunotherapy in both transplantation and autoimmunity. A major drawback in vivo is their potential to mature during infections or inflammation, which would con
Externí odkaz:
https://doaj.org/article/4b55c35e6abe4b36b2f4cc146eb5b5b0
Autor:
Timothy M. Dekker, Kimberly H. McVeigh, James C. Braxton, Ryan Cudahy, Thomas G. Berger, Tara J. Brigham
Publikováno v:
Clinical Journal of Sport Medicine.
OBJECTIVE Review the use of upper-extremity orthoses and casts after injuries to the wrist and hand in the pediatric, adolescent, and young adult population. The common injuries reviewed include pediatric distal radius fractures, scaphoid fractures,
Autor:
Erwin Strasser, Stefanie Gross, Karl Sotlar, Lucie Heinzerling, Stefan Schliep, Ina Haendle, Pierre Coulie, Erwin S. Schultz, Steve Voland, Gerold Schuler, Peter Dankerl, Rolf Janka, Beatrice Schuler-Thurner, Thomas G. Berger, Michael Erdmann
Publikováno v:
JCI insight. 2(8)
Background Reports on long-term (≥10 years) effects of cancer vaccines are missing. Therefore, in 2002, we initiated a phase I/II trial in cutaneous melanoma patients to further explore the immunogenicity of our DC vaccine and to establish its long
Autor:
Jolanta Kolodziejek, Thomas G. Berger, Norbert Nowotny, Suhail Al-Salam, Mohammed Rizwan Sohail
Publikováno v:
Journal of Cutaneous Pathology. 35:603-607
Background: Ecthyma contagiosum (orf) is caused by an epitheliotropic parapox virus. It is a zoonosis usually transmitted to humans from affected sheep or goat through direct contact or contaminated fomites. Methods: We report a 36-year-old patient w
Autor:
Richard A. G. Smith, Curt Carste, Gerold Schuler, Beatrice Schuler-Thurner, Eckhart Kaempgen, Thomas G. Berger, Erwin Strasser
Publikováno v:
Journal of Immunological Methods. 298:61-72
Dendritic cells (DC) are promising tools for the immunotherapy of cancer. The induction of tumor-specific T cells and clinical regressions have already been observed in early phase I/II vaccination trials. As DC vaccination is now facing trials with
Autor:
Per thor Straten, Jürgen C. Becker, Mads Hald Andersen, Ulf R. Rapp, Sine Reker, Uwe Trefzer, Thomas G. Berger, Joachim Fensterle, Dirk Schadendorf, Roland Houben, Selma Ugurel, Per Guldberg, Eva-B. Bröcker
Publikováno v:
Cancer Research. 64:5456-5460
Activating BRAF somatic missense mutations within the kinase domain are present in 60–66% of melanomas. The vast majority of these represent a single substitution of glutamate for valine (V599E). Here, we demonstrate spontaneous HLA-B*2705-restrict
Autor:
Werner Hohenberger, Gerold Schuler, Beatrice Schuler-Thurner, Per thor Straten, Thomas G. Berger, Jürgen C. Becker, Nicolas Bauer, Ina Haendle, Matthias Lüftl, Lars Østergaard Pedersen, David Schrama
Publikováno v:
International Journal of Cancer. 111:229-237
Anticancer immune therapies aim at the induction of tumor-specific T cells, which ultimately should kill tumor cells. The effector cells should, therefore, not only exert cytotoxic activity but also home to and infiltrate the tumor site. Hence, monit
Autor:
Kris Thielemanns, Thomas G. Berger, Beatrice Schuler-Thurner, Vincent Stroobant, Erwin S. Schultz, Gerold Schuler, Lars Jenne, Pierre van der Bruggen
Publikováno v:
The Journal of Immunology. 172:1304-1310
Recently, we have demonstrated that tumor-specific CD4+ Th cell responses can be rapidly induced in advanced melanoma patients by vaccination with peptide-loaded monocyte-derived dendritic cells. Most patients showed a T cell reactivity against a mel
Autor:
Jürgen Zingsem, Erwin Strasser, Robert Zimmermann, Beatrice Schuler-Thurner, Jürgen Ringwald, Volker Weisbach, Thomas G. Berger, Reinhold Eckstein
Publikováno v:
Transfusion. 43:1309-1316
BACKGROUND: Monocytes collected by leukapheresis are increasingly used for dendritic cell (DC) culture in cell factories suitable for DC vaccination in cancer. STUDY DESIGN AND METHODS: Using modified MNC programs on two apheresis systems (Cobe Spect
Autor:
Peter Thumann, Thomas G. Berger, Gerold Schuler, Isabelle Moc, Lars Jenne, Jens Y. Humrich, Erwin S. Schultz
Publikováno v:
Journal of Immunological Methods. 277:1-16
Dendritic cells (DC) based vaccinations have been widely used for the induction of anti-tumoral immunity in clinical studies. Antigen loading of DC with whole tumor cell preparations is an attractive method whenever tumor cell material is available.