Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Thomas Funck‐Brentano"'
Autor:
Emmanuel Seront, An Van Damme, Catherine Legrand, Annouk Bisdorff-Bresson, Philippe Orcel, Thomas Funck-Brentano, Marie-Antoinette Sevestre, Anne Dompmartin, Isabelle Quere, Pascal Brouillard, Nicole Revencu, Martina De Bortoli, Frank Hammer, Philippe Clapuyt, Dana Dumitriu, Miikka Vikkula, Laurence M. Boon
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
BACKGROUND Slow-flow vascular malformations frequently harbor activating mutations in the PI3K/AKT/mTOR cascade. Phase II trials pinpointed sirolimus effectiveness as a drug therapy. Efficacy and safety of sirolimus thus need to be evaluated in large
Externí odkaz:
https://doaj.org/article/b4013dff8ad94c219c38422656c3b99e
Autor:
Stéphanie Fabre, Morgane Bourmaud, Guillaume Mabilleau, Ruben Goulet, Aude Couturier, Alexandre Dentel, Serge Picaud, Thomas Funck‐Brentano, Corinne Collet, Martine Cohen‐Solal
Publikováno v:
JBMR Plus, Vol 7, Iss 6, Pp n/a-n/a (2023)
ABSTRACT Early‐onset osteoporosis (EOOP) has been associated with several genes, including LRP5, coding for a coreceptor in the Wnt pathway. Variants in LRP5 were also described in osteoporosis pseudoglioma syndrome, combining severe osteoporosis a
Externí odkaz:
https://doaj.org/article/16e7e35c1bb8432886e6622ee484f9ee
Publikováno v:
RMD Open, Vol 9, Iss 1 (2023)
Osteoporosis is a common non-communicable disease with enormous societal costs. Antiosteoporosis medications have been proven efficacious in reducing the refracture rate and mortality; moreover, we have now convincing evidence about the cost-effectiv
Externí odkaz:
https://doaj.org/article/253b9135f5d84ef0a63ac6470bfaa319
Autor:
Caroline Caetano da Silva, Manon Ricquebourg, Philippe Orcel, Stéphanie Fabre, Thomas Funck‐Brentano, Martine Cohen‐Solal, Corinne Collet
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Background Early‐onset osteoporosis (EOOP) is defined by low bone mineral density (BMD), which increases the risk of fracture. Although the prevalence of osteoporosis at a young age is unknown, low BMD is highly linked to genetic backgroun
Externí odkaz:
https://doaj.org/article/c601e16d66eb4054988173adaf84ed6c
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100812- (2021)
Externí odkaz:
https://doaj.org/article/442ecd8528a24b0a84d6929ea12c5018
Autor:
Bastien Leger, Agnes Ostertag, Thomas Funck-Brentano, Caroline Marty, Corinne Collet, Martine Cohen-Solal
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100813- (2021)
Externí odkaz:
https://doaj.org/article/a1fb3e90593442c393cbfe78b2efbd12
Autor:
Caroline Caetano, Manon Ricquebourg, Thomas Funck-Brentano, Philippe Orcel, Martine Cohen-Solal, Corinne Collet
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 100830- (2021)
Externí odkaz:
https://doaj.org/article/b5e59d09e6a74323a970300c690974c8
Autor:
Thomas Funck-Brentano, Louise Grahnemo, Ola Hjelmgren, John Brandberg, Göran Bergström, Claes Ohlsson
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100701- (2020)
Externí odkaz:
https://doaj.org/article/999cb5e394f0474cb3a63fa0c842f63d
Publikováno v:
Endocrine Connections, Vol 9, Iss 4, Pp R93-R101 (2020)
Mineral and bone diseases (MBD) are predominant in patients with chronic kidney disease (CKD) and lead to several bone manifestations, from pain to skeletal fractures. Cumulative traditional clinical risk factors, such as age and gender, in addition
Externí odkaz:
https://doaj.org/article/a4664d82855a4d38a0becc4c2490ac47
Autor:
Hilène Lin, Eric Hay, Augustin Latourte, Thomas Funck-Brentano, Wafa Bouaziz, Hang-Korng Ea, Abdel-Majid Khatib, Pascal Richette, Martine Cohen-Solal
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Cartilage loss in osteoarthritis (OA) results from altered local production of growth factors and metalloproteases (MMPs). Furin, an enzyme involved in the protein maturation of MMPs, might regulate chondrocyte function. Here, we tested the
Externí odkaz:
https://doaj.org/article/e1fe44008e4a4387b656a1af39f60073