Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thomas Fixemer"'
Autor:
Barbara A. Niemeyer, Thomas Fixemer, Nina Himmerkus, Helmut Bonkhoff, Veit Flockerzi, Ulrich Wissenbach
Publikováno v:
Biochemical and Biophysical Research Communications. 322:1359-1363
Life expectancy for patients suffering from prostate cancer is inversely correlated with the degree of extraprostatic metastasis. In order to find pharmacological tools to treat this aggressive growth it is important to define targets whose expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762cc9a99edf6e00c916195aa4ffd5ec
https://doi.org/10.1016/j.bbrc.2004.08.042
https://doi.org/10.1016/j.bbrc.2004.08.042
Publikováno v:
The Prostate. 53:118-123
BACKGROUND Neuroendocrine (NE) differentiation has been implicated in prostate cancer progression and hormone therapy failure. It has been shown that prostate cancer cells with NE features lack proliferation activity in vitro and in vivo. The current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f6ad0aa6e6baa859a24567e4a5fed38
https://doi.org/10.1002/pros.10133
https://doi.org/10.1002/pros.10133
Publikováno v:
The Prostate. 45:36-41
BACKGROUND The recent discovery of the classical estrogen receptor α (ERα) in androgen-insensitive prostate cancer has shed new light on the role of estrogens in endocrine therapy failure. To get more information on downstream events of estrogen si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7a536058cd71a1d339959ad01ecb48
https://doi.org/10.1002/1097-0045(20000915)45:1<36::aid-pros4>3.0.co
https://doi.org/10.1002/1097-0045(20000915)45:1<36::aid-pros4>3.0.co
Publikováno v:
The American Journal of Pathology. 155:641-647
Estrogens have been implicated in prostatic cancerogenesis and tumor progression. The mechanisms underlying estrogen signaling in human prostate tissue, however, remain poorly understood. Using immunohistochemical and in situ hybridization (ISH) tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3feaea6a9bc4d6222db4c736c41ebe3
https://doi.org/10.1016/s0002-9440(10)65160-7
https://doi.org/10.1016/s0002-9440(10)65160-7
Autor:
Claudia Pföhler, Steven Dooley, Volker Jung, Helmut Bonkhoff, Thomas Fixemer, Klaus Remberger
Publikováno v:
The Prostate. 36:143-150
BACKGROUND Recent immunohistochemical data have shown that invasive prostate cancer cells are separated from the host tissue by basement membranes (BM), and express associated adhesive molecules that bind to these de novo synthesized extracellular ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2a4b4e20bf943a18c19cd0aba8bd459
https://doi.org/10.1002/(sici)1097-0045(19980801)36:3<143::aid-pros1>3.0.co
https://doi.org/10.1002/(sici)1097-0045(19980801)36:3<143::aid-pros1>3.0.co
Autor:
Michael Veith, Günter R. Fuhr, Paul W. Dyce, Stefan Lötters, Martin Paulus, Oliver A. Ryder, Paul Müller, Thomas Fixemer, Daniel H. Rapoport, Katarina Jewgenow, Gordon Mcgregor Reid, David M. Rawson, Thomas Schmitt, Robert A. Browne, Ann G. Clarke, Rhiannon E. Lloyd, Brunhilde Blömeke, Jennifer Ringleb, Dominik Lermen, Gabriele Spörl, William V. Holt
Publikováno v:
Molecular ecology. 18(6)
Cryobanking, the freezing of biological specimens to maintain their integrity for a variety of anticipated and unanticipated uses, offers unique opportunities to advance the basic knowledge of biological systems and their evolution. Notably, cryobank
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bceed4612823cbf05208524f2f799e3
https://pubmed.ncbi.nlm.nih.gov/19207252
https://pubmed.ncbi.nlm.nih.gov/19207252
Publikováno v:
Virchows Archiv. 434:71-73
In situ DNA fragmentation assays have proved to be particularly useful in the detection of apoptosis in routinely processed, paraffin-embedded tissue sections. In the present study, a triple-antigen labelling technique was performed to demonstrate DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c157b456067459f53fca3c6ab1c5c80e
https://doi.org/10.1007/s004280050307
https://doi.org/10.1007/s004280050307
Publikováno v:
Oncogene. 22(49)
Members of the TRP superfamily of cation channels have homeostatic and regulatory functions in cells and changes in their expression may contribute to malignant growth. Previously, we have demonstrated that the gene of the Ca2+-selective cation chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f085a396a345013730e975fe4ae9320
https://pubmed.ncbi.nlm.nih.gov/14586412
https://pubmed.ncbi.nlm.nih.gov/14586412
Autor:
Thomas Fixemer, Joern Kamradt, Sascha Kalkbrenner, Carsten Drosse, Helmut Bonkhoff, Jan Lehmann, Michael Stoeckle, Bernd Wullich, Volker Rohde, Ramona Lensch
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 83(5)
Because the mechanisms of telomerase activation in prostate cancer are mainly unknown, we investigated the relationships between telomerase activity and expression levels of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55340120739ce57b0a0f4398d76d3916
https://pubmed.ncbi.nlm.nih.gov/12746472
https://pubmed.ncbi.nlm.nih.gov/12746472
Publikováno v:
The Prostate. 54(2)
BACKGROUND. Estrogen signaling mediated by the estrogen receptor beta (ERb) has potential implications in normal and abnormal prostate growth. Few studies have addressed this issue in human prostate tissue leaving conflicting results on the immunoloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12269252e347ca0e14f15aef56d3453
https://pubmed.ncbi.nlm.nih.gov/12497580
https://pubmed.ncbi.nlm.nih.gov/12497580