Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Thomas F.X. Collins"'
Autor:
M. Ramos-Valle, T.N. Black, Robert L. Sprando, Nicholas Olejnik, Thomas F.X. Collins, Dennis I. Ruggles
Publikováno v:
Food and Chemical Toxicology. 45:1606-1613
Acute toxicity of a single oral dose of sodium arsenite (As), administered in half and half cream (HH), was assessed in male and non-pregnant female rats (0.41, 4.1, 41.0 and 410.0 mg/kg body weight) and pregnant rats (0.41, 4.1 and 41.0 mg/kg body w
Autor:
T.N. Black, J.I. Rorie, Dennis I. Ruggles, Nicholas Olejnik, Robert L. Sprando, Robert M. Eppley, Fred A. Hines, Thomas F.X. Collins
Publikováno v:
Food and Chemical Toxicology. 44:747-757
Deoxynivalenol (DON, vomitoxin), is one of the most common contaminants of cereal grains world-wide. The effects of DON on fetal development were assessed in Charles River Sprague–Dawley rats. Pregnant female rats were gavaged once daily with DON a
Autor:
Saura C. Sahu, P.P. Sapienza, Paddy Wiesenfeld, Thomas F.X. Collins, M.W. O'Donnell, C.E. Ford, Ivan A. Ross, Robert L. Sprando, Thomas J. Flynn, Chung S Kim
Publikováno v:
Food and Chemical Toxicology. 44:579-587
Androstenedione, a steroidal dietary supplement taken to enhance athletic performance, could affect serum and liver lipid metabolism, induce liver toxicity or alter inflammatory response depending on dose and duration of exposure. Pregnancy could fur
Autor:
Thomas F.X. Collins
Publikováno v:
Current Pharmaceutical Design. 12:1449-1465
Birth defects and other adverse outcomes of pregnancy have been known since before the industrial age, but the need for guidelines to test chemicals to which pregnant women might be exposed was defined by the thalidomide tragedy in the 1950s and earl
Autor:
Thomas F.X. Collins, Ronald H. Gray, R. Woodrow Setzer, Ulrike Luderer, Kimberley A. Treinen, George P. Daston, Andrew F. Olshan, Roel Vermeulen, Franklin E. Mirer, Lawrence J. Fischer
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 77:110-193
Autor:
T.N. Black, Robert L. Sprando, Robert M. Eppley, J.I. Rorie, Nicholas Olejnik, Thomas F.X. Collins, Dennis I. Ruggles
Publikováno v:
Food and Chemical Toxicology. 43:623-635
The effect of deoxynivalenol (DON) exposure on male reproductive function was assessed in the rat. Male rats were divided into a control group (n=15 rats) and four treatment groups (0.5 mg/kg, n=15; 1.0 mg/kg, n=15; 2.5 mg/kg, n=15; and 5.0 mg/kg DON
Autor:
P.P. Sapienza, Saura C. Sahu, Chung S Kim, Thomas F.X. Collins, M.W. O'Donnell, Ivan A. Ross, Robert L. Sprando, Thomas J. Flynn, Paddy Wiesenfeld
Publikováno v:
Food and Chemical Toxicology. 43:537-542
It is unknown whether androstenedione, a steroidal dietary supplement taken to enhance athletic performance, can affect physiological hormone levels by altering liver enzyme activities that metabolize steroid hormones. Altered hormone levels could be
Autor:
P.P. Sapienza, Robert L. Sprando, Thomas J. Flynn, Paddy L. Wiesenfeld, M.W. O'Donnell, Saura C. Sahu, Thomas F.X. Collins, Chung S Kim, Ivan A. Ross
Publikováno v:
Food and Chemical Toxicology. 43:341-344
Androstenedione, a naturally occurring steroid hormone, is a dietary supplement used to enhance athletic performance. Little is known, however, about the safety of its use by young adults including women of child bearing age. To test the possible hep
Autor:
Dennis I. Ruggles, T.N. Black, Erich Grundel, Nicholas Olejnik, Robert L. Sprando, Thomas F.X. Collins
Publikováno v:
Food and Chemical Toxicology. 42:917-924
This study was conducted to characterize the effect of androstenedione on estrous cyclicity, mating behavior and fetal development. Thirty-day old rats received corn oil alone or androstenedione (in corn oil) at one of four concentrations (0, 1.0, 5.
Autor:
Nicholas Olejnik, Robert L. Sprando, Thomas J. Flynn, Paddy Wiesenfeld, T.N. Black, Uma S. Babu, M.W. O'Donnell, Thomas F.X. Collins
Publikováno v:
Food and Chemical Toxicology. 41:841-855
The effects of dietary flaxseed (FS), and defatted flaxseed meal (FLM) on serum and tissue fatty acid profiles were investigated. Pregnant Sprague–Dawley rats were fed AIN-93 based diets balanced in calories, fat, nitrogen, and fiber. Diets contain