Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thomas F.W. Horn"'
Autor:
Mohammad Fahad Haroon, Ambrin Fatima, Susanne Schöler, Anne Gieseler, Thomas F.W. Horn, Elmar Kirches, Gerald Wolf, Peter Kreutzmann
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 3, Pp 237-250 (2007)
Leber’s hereditary optic neuropathy (LHON) is a retinal neurodegenerative disorder caused by mitochondrial DNA point mutations. Complex I of the respiratory chain affected by the mutation results in a decrease in ATP and an increase of reactive oxy
Externí odkaz:
https://doaj.org/article/03af3fd5616847d384302768b5a956f7
Autor:
Ambrin Fatima, M.F. Haroon, Gerald Wolf, Peter Kreutzmann, Elmar Kirches, Thomas F.W. Horn, Anne Gieseler, Susanne Schöler
Publikováno v:
Neurobiology of Disease, Vol 28, Iss 3, Pp 237-250 (2007)
Leber's hereditary optic neuropathy (LHON) is a retinal neurodegenerative disorder caused by mitochondrial DNA point mutations. Complex I of the respiratory chain affected by the mutation results in a decrease in ATP and an increase of reactive oxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3aead9a9897121fd8fc0cfaf12871e
http://www.sciencedirect.com/science/article/pii/S0969996107001635
http://www.sciencedirect.com/science/article/pii/S0969996107001635
Publikováno v:
Cell Calcium. 39:387-400
The permeability transition pore (PTP) and the ATP-dependent potassium (mtK-ATP) channel of mitochondria are known to play key roles in mitochondrially mediated apoptosis. We investigated how modulation of the permeability transition pore (PTP) and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41592371d23413afa544d943d6b3121c
https://doi.org/10.1016/j.ceca.2006.01.001
https://doi.org/10.1016/j.ceca.2006.01.001
Autor:
Zsombor Lacza, H. Redl, Thomas F.W. Horn, Eszter Pankotai, Andrey V. Kozlov, Márk Kollai, Gerald Wolf, David W. Busija, Csaba Szabó, Attila Csordas
Publikováno v:
Free Radical Research. 40:369-378
We measured the contribution of mitochondrial nitric oxide synthase (mtNOS) and respiratory chain enzymes to reactive nitrogen species (RNS) production. Diaminofluorescein (DAF) was applied for the assessment of RNS production in isolated mouse brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ca2fd4f46a3edd6793e6bd0301978a
https://doi.org/10.1080/10715760500539139
https://doi.org/10.1080/10715760500539139
Publikováno v:
Neuroscience Letters. 393:113-118
We investigated to what extent the antioxidative hydroxystilbene oxyresveratrol (trans-2,3',4,5'-tetrahydroxystilbene, OXY), that we showed earlier to be strongly neuroprotective in a stroke model, may cross the blood-brain barrier (BBB) in healthy r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a5478e652f0a6709cd719a61c2f2e3
https://doi.org/10.1016/j.neulet.2005.09.081
https://doi.org/10.1016/j.neulet.2005.09.081
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 38:610-620
The transmembrane tyrosine-specific protein kinase TrkB has been shown to serve as a receptor for the neurotrophic factors BDNF and NT-4. Neurotrophin binding to TrkB isoformes mediates many intracellular signaling pathways, including calcium signall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dd14141bdcb5ac33968a7ad02b6569
https://doi.org/10.1016/j.biocel.2005.10.024
https://doi.org/10.1016/j.biocel.2005.10.024
Publikováno v:
Brain Research. 1060:1-15
Nitric oxide (NO) is a molecule that plays a prominent role in neurotoxic as well as neuroprotective pathways. Here, we investigated the effects of NO on potentially excitotoxic glutamate-induced intracellular calcium ([Ca2+]i) dynamics. Our hypothes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3e37beec7054d55a599e559a4de20c
https://doi.org/10.1016/j.brainres.2005.07.065
https://doi.org/10.1016/j.brainres.2005.07.065
Autor:
Peter Lorenz, Thomas F.W. Horn, Jens Martens-Lobenhoffer, Harry Schmidt, Gerald Wolf, Michael Zeh
Publikováno v:
Free Radical Research. 39:535-545
We investigated the antioxidant and radical scavenging activity of polyphenolic isochromans. To assess the relation between structure and scavenging properties the natural occurring 1-(3'-methoxy-4'-hydroxy)phenyl-6,7-dihydroxy-isochroman (ISO-3, thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927985e190967ac3d50a308618987a8c
https://doi.org/10.1080/10715760500073733
https://doi.org/10.1080/10715760500073733
Autor:
Sanjoy Roychowdhury, Jorge P. Figueroa, Eszter M. Horváth, Zsombor Lacza, Jie Zhang, Thomas F.W. Horn, James A. Snipes, Csaba Szabó, Márk Kollai, David W. Busija
Publikováno v:
Journal of Neurochemistry. 90:942-951
Based on our initial finding that the nitric oxide (NO) sensitive fluorochrome diaminofluorescein (DAF) was localized to mitochondria in cultured primary neurons, we investigated whether brain mitochondria produce NO through a mitochondrial NO syntha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6816075a5cfc49bc5ba5edb8d9b709
https://doi.org/10.1111/j.1471-4159.2004.02553.x
https://doi.org/10.1111/j.1471-4159.2004.02553.x
Autor:
Philip M. Bull, Thomas F.W. Horn, Mike Ludwig, Colin H. Brown, Rainer Landgraf, Carsten T. Wotjak, Nicolas Singewald, Mario Engelmann
Publikováno v:
European Journal of Neuroscience. 19:601-608
Recently we reported that a single social defeat experience triggers the release of oxytocin (OXT) from somata and dendrites, but not axon terminals, of neurons of the hypothalamic-neurohypophysial system. To further investigate the regulatory mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26527111ab71642c52b9aa57dee4bb67
https://doi.org/10.1111/j.1460-9568.2004.03151.x
https://doi.org/10.1111/j.1460-9568.2004.03151.x