Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Thomas F. Warner"'
Autor:
Aisha M. Mergaert, Michael F. Denny, Brock Kingstad-Bakke, Mandar Bawadekar, S. Janna Bashar, Thomas F. Warner, Marulasiddappa Suresh, Miriam A. Shelef
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
The peptidylarginine deiminases (PADs) and the citrullinated proteins that they generate have key roles in innate immunity and rheumatoid arthritis, an inflammatory arthritis with antibodies that target citrullinated proteins. However, the importance
Externí odkaz:
https://doaj.org/article/6fd59b6353344d72996e41b25de3b5fa
Publikováno v:
Methods in cell biology. 168
Rheumatoid arthritis is an incurable chronic inflammatory disease for which the pathophysiology is not fully understood, and treatment options are flawed. Thus, animal models are used to dissect disease pathogenesis and to develop improved therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19c93a6c9091a4a7c52987850b7553a4
https://pubmed.ncbi.nlm.nih.gov/35366979
https://pubmed.ncbi.nlm.nih.gov/35366979
Publikováno v:
Methods in Cell Biology ISBN: 9780323899451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80fc3567e29674aeadf1f3e3076cc59d
https://doi.org/10.1016/bs.mcb.2021.12.012
https://doi.org/10.1016/bs.mcb.2021.12.012
Autor:
Stephane Esnault, Michael Feldman, James E. Gern, Thomas F. Warner, Rebecca A. Brockman-Schneider, Daniel J. Jackson, Mengyao Niu, Matthew Freeman, Carole Ober, Nizar N. Jarjour, Gregory C. Kujoth, Jatin M. Vyas, Darin L. Wiesner, Bruce S. Klein, Hongmei Mou, Nancy P. Keller, Richard M. Merkhofer, Michael D. Evans
Publikováno v:
Cell Host Microbe
Airway epithelium is the first body surface to contact inhaled irritants and report danger. Here, we report how epithelial cells recognize and respond to aeroallergen alkaline protease 1 (Alp1) of Aspergillus sp., because proteases are critical compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26ce5d610f3de2b77a057298d5f5b6f
https://europepmc.org/articles/PMC7305569/
https://europepmc.org/articles/PMC7305569/
Autor:
Chad J. Johnson, Miriam A. Shelef, Mandar Bawadekar, Jeniel E. Nett, Thomas F. Warner, Claus Henrik Nielsen, Dres Damgaard, Daeun Shim, Ger J. M. Pruijn, Ryan Rebernick
Publikováno v:
Journal of Autoimmunity, 80, pp. 39-47
Journal of Autoimmunity, 80, 39-47
Journal of Autoimmunity, 80, 39-47
Citrullination, the post-translational conversion of arginines to citrullines, may contribute to rheumatoid arthritis development given the generation of anti-citrullinated protein antibodies (ACPAs). However, it is not known which peptidylarginine d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c143dc8d3f0c85a6866704fb7d32bc19
https://doi.org/10.1016/j.jaut.2017.01.006
https://doi.org/10.1016/j.jaut.2017.01.006
Autor:
Greg C. Kujoth, Thomas F. Warner, Michal Feldman, Jatin M. Vyas, Hongmei Mou, C. Ober, S. J. Esnault, R. Brockman Schneider, Nizar N. Jarjour, Michael D. Evans, Daniel J. Jackson, James E. Gern, Darin L. Wiesner, Bruce S. Klein, M. J. Freeman, Richard M. Merkhofer
SUMMARYAirway epithelium is the first body surface to contact inhaled irritants and report danger. We studied how epithelial cells recognize and respond to protease, which is a critical component of many allergens that provoke asthma. In a murine mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b21546b3a9683c6b586a7894449e359
https://doi.org/10.1101/773382
https://doi.org/10.1101/773382
Publikováno v:
Pathogens and disease. 75(6)
The role that cytokines play in the induction of Lyme arthritis is gradually being delineated. We showed previously that severe arthritis developed in a T-cell-driven murine model, even in mice lacking interleukin-17A (IL-17A) and administered anti-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7ec5c420e7861660ad762a91be23f5
https://pubmed.ncbi.nlm.nih.gov/28859307
https://pubmed.ncbi.nlm.nih.gov/28859307
Publikováno v:
Pathogens and Disease. 75
The immune mechanisms responsible for development of Lyme arthritis are partially understood with interleukin-17 (IL-17) and gamma-interferon (IFN-γ) playing a generally accepted role. Elevated levels of IL-17 and/or IFN-γ have been reported in sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e2c3b5a79970c11a4a65e7d5f1285f
https://doi.org/10.1093/femspd/ftx014
https://doi.org/10.1093/femspd/ftx014
Autor:
Catriona A. Wagner, Thomas F. Warner, David J. Beebe, Jeremy Sokolove, Yanming Wang, Lauren J. Lahey, William H. Robinson, Miriam A. Shelef, Anna Huttenlocher, Eric K. Sackmann
Publikováno v:
Arthritis & Rheumatology. 66:1482-1491
Rheumatoid arthritis has long been known to be an inflammatory arthritis, with tumor necrosis factor α (TNFα) playing a leading role. However, more recent evidence demonstrates that rheumatoid arthritis is also an autoimmune disease characterized b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba54aeb29d4ef35d379876242ffd841a
https://doi.org/10.1002/art.38393
https://doi.org/10.1002/art.38393
Autor:
J. Scott Fites, Nydiaris Hernández-Santos, Marcel Wüthrich, Andrew J. McDermott, Thomas F. Warner, Darin L. Wiesner, Bruce S. Klein
Publikováno v:
Cell Host & Microbe. 25:630
Lung epithelial cells (LECs) are strategically positioned in the airway mucosa to provide barrier defense. LECs also express pattern recognition receptors and a myriad of immune genes, but their role in immunity is often concealed by the activities o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926f9c9459505f464a9039b732647e2b
https://doi.org/10.1016/j.chom.2019.03.013
https://doi.org/10.1016/j.chom.2019.03.013