Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Thomas F. Schilling"'
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Research on the genetic mechanisms underlying human skeletal development and disease have largely relied on studies in mice. However, recently the zebrafish has emerged as a popular model for skeletal research. Despite anatomical differences such as
Externí odkaz:
https://doaj.org/article/6a3d0d6d5cb14e158c87f4fd360d6e3e
Autor:
Laura A. Hendrick, Grace A. Carter, Erin H. Hilbrands, Brian P. Heubel, Thomas F. Schilling, Pierre Le Pabic
Publikováno v:
EvoDevo, Vol 10, Iss 1, Pp 1-18 (2019)
Abstract Background Melanic patterns such as horizontal stripes, vertical bars and spots are common among teleost fishes and often serve roles in camouflage or mimicry. Extensive research in the zebrafish model has shown that the development of horiz
Externí odkaz:
https://doaj.org/article/0773904ace0f4efa92c4e5b70d19101b
Publikováno v:
Cells, Vol 10, Iss 8, p 2005 (2021)
Aquaporin 0 (AQP0) is the most abundant lens membrane protein, and loss of function in human and animal models leads to cataract formation. AQP0 has several functions in the lens including water transport and adhesion. Since lens optics rely on stric
Externí odkaz:
https://doaj.org/article/dc90228119f74cdd9240a24d07d26077
Publikováno v:
EvoDevo, Vol 7, Iss 1, Pp 1-26 (2016)
Abstract Background Cichlid fishes from the Rift Lakes of East Africa have undergone the most spectacular adaptive radiations in vertebrate history. Eco-morphological adaptations in lakes Victoria, Malawi and Tanganyika have resulted in a vast array
Externí odkaz:
https://doaj.org/article/1ab8552e74224847877da8744a6f0cde
Abstract QS43: Blepharophimosis Ptosis Epicanthus Inversus Syndrome Caused by a ZC3H13 Gene Mutation
Autor:
Daniel M. Balkin, MD, PhD, Carol Nelson-Williams, BS, MS, Brandon J. Sumpio, BA, Daryl A. Scott, MD, PhD, Pierre Le Pabic, PhD, Thomas F. Schilling, PhD, Richard P. Lifton, MD, PhD, Deepak Narayan, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 6, Iss 4S, Pp 142-143 (2018)
Externí odkaz:
https://doaj.org/article/8c39f2718d30424c834d4d5e59b69810
Publikováno v:
Development. 150
Non-canonical/β-catenin-independent Wnt signaling plays crucial roles in tissue/cell polarity in epithelia, but its functions have been less well studied in mesenchymal tissues, such as the skeleton. Mutations in non-canonical Wnt signaling pathway
Autor:
Thomas F Schilling, Pierre Le Pabic
Publikováno v:
eLife. 11
A newly discovered enhancer region may have allowed vertebrates to evolve the ability to open and close their jaws.
Autor:
James E. Baumgardner, Thomas Hachenberg, Anders Larsson, Moritz Kretzschmar, Göran Hedenstierna, Thomas F. Schilling, Alf Kozian
Publikováno v:
Anesthesiology. 135:1042-1054
Background Kinetics of the uptake of inhaled anesthetics have been well studied, but the kinetics of elimination might be of more practical importance. The objective of the authors’ study was to assess the effect of the overall ventilation/perfusio
Autor:
Moritz Kretzschmar, Anders Larsson, James E. Baumgardner, Göran Hedenstierna, Thomas Hachenberg, Alf Kozian, Thomas F. Schilling
Publikováno v:
Anesthesiology. 135:1027-1041
Background Previous studies have established the role of various tissue compartments in the kinetics of inhaled anesthetic uptake and elimination. The role of normal lungs in inhaled anesthetic kinetics is less understood. In juvenile pigs with norma
Autor:
Christian Pierce, Pierre Le Pabic, Thomas F. Schilling, Nicholas Hall-Ruiz, Benjamin Powell, Alexandra Kite, Samantha Reynolds
Publikováno v:
Developmental Dynamics. 250:1796-1809
Background Hand genes are required for the development of the vertebrate jaw, heart, peripheral nervous system, limb, gut, placenta and decidua. Two Hand paralogues, Hand1 and Hand2, are present in most vertebrates, where they mediate different funct