Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Thomas F. Necheles"'
Autor:
Thomas F. Necheles, Carol Crowley
Publikováno v:
Clinics in Perinatology. 3:161-175
Diagnosis and management of the most common hereditary disorders of the erythrocyte are discussed. These congenital defects may continue to present problems through infancy and childhood. These problems may be anticipated and ameliorated or prevented
Autor:
Bahman Emami, Henry H. Banks, Won H. Oh, Jorge C. Paradelo, Thomas F. Necheles, Ivanka Tchakarova, John E. Munzenrider
Publikováno v:
Radiology. 125:497-502
The rationale for prebiopsy and preoperative irradiation in a multimodal approach to treatment of osteosarcoma is presented. Six patients with osteosarcoma underwent preoperative irradiation, amputation, and elective chemotherapy. Five of these also
Publikováno v:
New England Journal of Medicine. 291:1351-1355
Presentation of Case A 12-month-old girl was admitted to the hospital because of a thoracoabdominal mass. She was born of a normal pregnancy, labor and delivery and was well until three months before admission, when she began to have diarrhea after e
Publikováno v:
Acta Paediatrica. 65:361-367
Carboxyhaemoglobin levels were measured in 250 consecutive, normal, term newborns and in a group of 75 severely jaundiced infants in an effort to assess the role of haemolysis in non-specific neonatal hyperbilirubinaemia--"Physiologic jaundice"-as we
Autor:
Donald M. Allen, Thomas F. Necheles
Publikováno v:
New England Journal of Medicine. 280:203-206
THE "Heinz-body anemias" are a group of hemolytic syndromes of diverse etiology with a common morphologic characteristic, first described by Heinz,1 of one or more inclusion bodies within affected ...
Publikováno v:
Blood. 28:501-512
1. Three siblings with Hb H thalassemia disease have been observed in a family in which 17 members from 3 generations have been examined. Four additional family members have α-thalassemia minor. 2. A genetic examination of the family provides furthe
Publikováno v:
The American Journal of Medicine. 49:125-132
A new variant of glucose-6-phosphate dehydrogenase (G-6-PD), G-6-PD Worcester, is described in a Caucasian family with associated congenital, nonspherocytic hemolytic anemia, absent erythrocyte G-6-PD activity and optic atrophy. The inheritance of th
Publikováno v:
The Journal of Pediatrics. 72:319-324
A genetically determined partial deficiency of the erythrocyte enzyme glutathioneperoxidase has been found in 4 unrelated newborn infants. This partial enzyme deficiency was found associated with a syndrome characterized by hyperbilirubinemia, increa
Publikováno v:
The American Journal of Medicine. 50:542-546
Defects of the hexosemonophosphate shunt-glutathione (HMP-GSH) pathways of the erythrocyte may lead to oxidative denaturation of hemoglobin and cell stroma with resulting hemolysis. The administration of oxidant drugs to subjects with such lesions pl
Autor:
William Dameshek, Thomas F. Necheles
Publikováno v:
Blood. 29:550-553
The in vitro synthesis of heme and globin has been studied in bone marrow cell suspensions obtained from five patients with Di Guglielmo syndrome. In all, a defect of heme synthesis was demonstrated, but globin synthesis was greatly reduced in only t