Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Thomas F. Moriarty"'
1
Akademický článek
Implant retention in a rabbit model of fracture-related infection: similar infection clearance but impaired bone healing in delayed compared to early infection
Autor: Jan Puetzler, Alejandro Vallejo Diaz, Georg Gosheger, Martin Schulze, Daniel Arens, Stephan Zeiter, Claudia Siverino, Robert G. Richards, Thomas F. Moriarty
Publikováno v: Bone & Joint Research, Vol 13, Iss 3, Pp 127-135 (2024)
Aims: Fracture-related infection (FRI) is commonly classified based on the time of onset of symptoms. Early infections (< two weeks) are treated with debridement, antibiotics, and implant retention (DAIR). For late infections (> ten weeks), guideline
Externí odkaz: https://doaj.org/article/c80e9fc44bba4f4a9b31bcde118dd37c
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2
Akademický článek
Development of bone seeker–functionalised microspheres as a targeted local antibiotic delivery system for bone infections
Autor: Stijn G. Rotman, Keith Thompson, Dirk W. Grijpma, Robert G. Richards, Thomas F. Moriarty, David Eglin, Olivier Guillaume
Publikováno v: Journal of Orthopaedic Translation, Vol 21, Iss , Pp 136-145 (2020)
Objective: Bone infections are challenging to treat because of limited capability of systemic antibiotics to accumulate at the bone site. To enhance therapeutic action, systemic treatments are commonly combined with local antibiotic-loaded materials.
Externí odkaz: https://doaj.org/article/71e34de8da77413c80178f6cde92c8a5
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3
Akademický článek
Poly(Aspartic Acid) Functionalized Poly(ϵ-Caprolactone) Microspheres with Enhanced Hydroxyapatite Affinity as Bone Targeting Antibiotic Carriers
Autor: Stijn G. Rotman, Thomas F. Moriarty, Benjamin Nottelet, Dirk W. Grijpma, David Eglin, Olivier Guillaume
Publikováno v: Pharmaceutics, Vol 12, Iss 9, p 885 (2020)
Bone infection is a feared complication for patients with surgically fixed bone fractures and local antibiotic delivery is important in prophylaxis and treatment of these infections. Recent studies indicated that Staphylococcus aureus can penetrate b
Externí odkaz: https://doaj.org/article/6cb5fd8208a347b7858ff14250fe7f30
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4
Peri‐anesthetic hypothermia in rodents: A factor to consider for accurate and reproducible outcomes in orthopedic device‐related infection studies
Autor: Caroline Constant, Thomas F. Moriarty, Daniel Arens, Brenna Pugliese, Stephan Zeiter
Publikováno v: Journal of Orthopaedic Research. 41:619-628
Orthopedic device-related infection (ODRI) preclinical models are widely used in translational research. Most ODRI models require induction of general anesthesia, which frequently results in hypothermia in rodents. This study aimed to evaluate the im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465cb0cae5b965b1368088df84937c63
https://doi.org/10.1002/jor.25397
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5
Current Concepts of Osteomyelitis: From Pathologic Mechanisms to Advanced Research Methods
Autor: Marloes I, Hofstee, Gowrishankar, Muthukrishnan, Gerald J, Atkins, Martijn, Riool, Keith, Thompson, Mario, Morgenstern, Martin J, Stoddart, Robert G, Richards, Sebastian A J, Zaat, Thomas F, Moriarty
Publikováno v: The American journal of pathology. 190(6)
Osteomyelitis is an inflammation of the bone and bone marrow that is most commonly caused by a Staphylococcus aureus infection. Much of our understanding of the underlying pathophysiology of osteomyelitis, from the perspective of both host and pathog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5669158066ae6da5f1c1e45246d21115
https://pubmed.ncbi.nlm.nih.gov/32194053
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6
Ozonated saline shows activity against planktonic and biofilm growing Staphylococcus aureus in vitro: a potential irrigant for infected wounds
Autor: Hayder, Al-Saadi, Inga, Potapova, Edward Tj, Rochford, Thomas F, Moriarty, Peter, Messmer
Publikováno v: Int Wound J
Infections associated with deep wounds require extensive surgical and medical care. New adjunctive treatments are required to aid in the eradication of the bacterial biofilms found on infected wounds and, in particular, any underlying hardware. Ozone
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed638ea966b0f5cb8db7d637d25bed46
https://pubmed.ncbi.nlm.nih.gov/25586644
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7
Two sets of inequalities among the principal invariants of the Cauchy-Green deformation tensors
Autor: Thomas F. Moriarty
Publikováno v: Journal of Elasticity. 1:87-90
Two sets of inequalities among the principal invariants of a third order positive definite Hermitian matrix are established. Application is made to the Cauchy-Green deformation tensors of continuum mechanics.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf8f5f265cd7c6c627dc48b50d530b3e
https://doi.org/10.1007/bf00045702
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9
Deformation of the diastolic left ventricle--II. Nonlinear geometric effects
Autor: Bruce R. Kubert, Arthur F. Grimm, Thomas F. Moriarty, Ronald F. Janz
Publikováno v: Journal of biomechanics. 7(6)
A finite element model for the rat left ventricle has been developed which is based on finite deformation elasticity theory: i.e. the model is not limited by assumptions relating to the magnitudes of extensions, shears and angles of rotation which ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37da4403676e29855f2acbe973bef1f7
https://pubmed.ncbi.nlm.nih.gov/4452676
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