Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas F. Gronauer"'
Autor:
Shu-Yu Chen, Michaela K. Fiedler, Thomas F. Gronauer, Olesia Omelko, Marie-Kristin von Wrisberg, Tao Wang, Sabine Schneider, Stephan A. Sieber, Martin Zacharias
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Staphylococcus aureus signal peptidase IB (SpsB) is an essential enzyme for protein secretion. While inhibition of its activity by small molecules is a well-precedented mechanism to kill bacteria, the mode of activation is however less under
Externí odkaz:
https://doaj.org/article/29fa57a779a04f2d86a49e6cf38e078d
Autor:
Josef Braun, Yudong Hu, Adrian T. Jauch, Thomas F. Gronauer, Julia Mergner, Nina C. Bach, Franziska R. Traube, Stefan Zahler, Stephan A. Sieber
Publikováno v:
JACS Au, Vol 4, Iss 5, Pp 1833-1840 (2024)
Externí odkaz:
https://doaj.org/article/668d895d9ae64ad2bc0bb39ee04103f1
Autor:
Carolin M.-L. Gleissner, Carolin L. Pyka, Wolfgang Heydenreuter, Thomas F. Gronauer, Carina Atzberger, Vadim S. Korotkov, Weiting Cheng, Stephan M. Hacker, Angelika M. Vollmar, Simone Braig, Stephan A. Sieber
Publikováno v:
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
Externí odkaz:
https://doaj.org/article/8a702a398cd544bc9174ef6ea10e4433
Publikováno v:
Angewandte Chemie. International Edition, 61 (10)
Approaches for profiling protease substrates are critical for defining protease functions, but remain challenging tasks. We combine genetic code expansion, photocrosslinking and proteomics to identify substrates of the mitochondrial (mt) human casein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bba05f4d769b2f051dcfb706a9a33e8
https://pubmed.ncbi.nlm.nih.gov/34847623
https://pubmed.ncbi.nlm.nih.gov/34847623
Autor:
Thomas F. Gronauer, Vadim S. Korotkov, Simone Braig, Weiting Cheng, Stephan A. Sieber, Carolin L. Pyka, Angelika M. Vollmar, Carolin M.-L. Gleissner, Carina Atzberger, Wolfgang Heydenreuter, Stephan M. Hacker
Publikováno v:
ACS Central Science
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
ACS Central Science, 5 (7)
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
ACS Central Science, 5 (7)
The natural product neocarzilin A (NCA) was discovered decades ago, and despite its potent cytotoxic effects no mode of action studies have been performed up to date. Synthesis of neocarzilins A, B, and C and a stereoisomer of NCA provided insights i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6908d47e680f0b9fc915a709aa2cd6
http://europepmc.org/articles/PMC6661975
http://europepmc.org/articles/PMC6661975
Autor:
Fritz E. Kühn, Angela Weigert Muñoz, Christian H. G. Jakob, Thomas F. Gronauer, Stephan A. Sieber, Kevin Meighen-Berger, Vanessa Weiß, Jonas F. Schlagintweit, João D. G. Correia, Matthias J. Feige
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 50(6)
Fluorescent Pd(II) and Pt(II) complexes bearing 4-methylene-7-methoxycoumarin (MMC) and 2,6-diispropylphenyl (Dipp) substituted NHC/1,2,3-triazole hybrid ligands are described. Depending on the reaction conditions two different ligand coordination mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6624cc31fe1236626925238e96083a6
https://pubmed.ncbi.nlm.nih.gov/33496310
https://pubmed.ncbi.nlm.nih.gov/33496310
Autor:
Thomas F. Gronauer, Carmine Capacchione, Katia Rodewald, Matthias Schmidt, David Hermann Lamparelli, Lucas Stieglitz, Hicran H. Güngör, Malte Winnacker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded86b8c655f93e9d14486cbca0f509b
https://mediatum.ub.tum.de/doc/1580139/document.pdf
https://mediatum.ub.tum.de/doc/1580139/document.pdf
Autor:
Thomas F. Gronauer, Stephan A. Sieber, Markus Lakemeyer, Mathias W. Hackl, Johanna Pachmayr, Vadim S. Korotkov, Martina Meßner, Melanie M Mandl
Publikováno v:
Chemical communications (Cambridge, England). 54(70)
Human caseinolytic protease P (hClpP) is important for degradation of misfolded proteins in the mitochondrial unfolded protein response. We here introduce tailored hClpP inhibitors that utilize a steric discrimination in their core naphthofuran scaff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadbce2d8f7afaeb09393f41b88b679c
https://pubmed.ncbi.nlm.nih.gov/30109319
https://pubmed.ncbi.nlm.nih.gov/30109319
Autor:
Thomas F. Gronauer, Bernhard Rieger, Leonhard Reinschlüssel, Hicran H. Güngör, Andreas Beringer, Stephan A. Sieber, Malte Winnacker
Publikováno v:
Macromolecular Rapid Communications. 40:1900091
In addition to their established usage in textiles, commodities, and automotives, classical polyamides (nylons) are recently becoming increasingly interesting for applications in (bio)medicine. This fact relies on many prosperous properties of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638c69da536a94fa066009b1a62c05d1
https://doi.org/10.1002/marc.201900091
https://doi.org/10.1002/marc.201900091