Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thomas F. Allison"'
Autor:
Duncan Baker, Adam J. Hirst, Paul J. Gokhale, Miguel A. Juarez, Steve Williams, Mark Wheeler, Kerry Bean, Thomas F. Allison, Harry D. Moore, Peter W. Andrews, Ivana Barbaric
Publikováno v:
Stem Cell Reports, Vol 7, Iss 5, Pp 998-1012 (2016)
Genetic changes in human pluripotent stem cells (hPSCs) gained during culture can confound experimental results and potentially jeopardize the outcome of clinical therapies. Particularly common changes in hPSCs are trisomies of chromosomes 1, 12, 17,
Externí odkaz:
https://doaj.org/article/b5a76d73b9de425994a516a51d117bcb
Autor:
Andrew J. Lund, Istvan Mody, John Huang, Inma Cobos, William E. Lowry, Marcos Otero-Garcia, Justin Langerman, Ranmal A. Samarasinghe, Kathrin Plath, Damon Polioudakis, Shan Sabri, Xiaofei Wei, Bennett G. Novitch, Daniel H. Geschwind, Thomas F. Allison
Publikováno v:
Stem cell reports, vol 16, iss 10
Stem Cell Reports
Stem Cell Reports
Summary The specification of inhibitory neurons has been described for the mouse and human brain, and many studies have shown that pluripotent stem cells (PSCs) can be used to create interneurons in vitro. It is unclear whether in vitro methods to pr
Autor:
Bennett G. Novitch, Momoko Watanabe, Arinnae Kurdian, Jessie E. Buth, Thomas F. Allison, William E. Lowry, Istvan Mody, Kathrin Plath, Jack M. Parent, Peyman Golshani, Osvaldo A. Miranda, Ranmal A. Samarasinghe, Simon Mitchell, Namie N. Fotion, Isabella Ferando, Michael J. Gandal
Publikováno v:
Nature neuroscience, vol 24, iss 10
Brain organoids represent a powerful tool for studying human neurological diseases, particularly those that affect brain growth and structure. However, many diseases manifest with clear evidence of physiological and network abnormality in the absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c288d4f42d433f0860576f9b81455b6d
https://escholarship.org/uc/item/8kj286zq
https://escholarship.org/uc/item/8kj286zq
Autor:
Kathrin Plath, Thomas F. Allison, William E. Lowry, Adrienne Grzenda, Rie Takahashi, Samuel J. Balin, Jeffrey D. Rawnsley, Shan Sabri
Publikováno v:
The Journal of investigative dermatology, vol 140, iss 4
J Invest Dermatol
J Invest Dermatol
The epidermis and its appendage, the hair follicle, represent an elegant developmental system in which cells are replenished with regularity because of controlled proliferation, lineage specification, and terminal differentiation. While transcriptome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b95d7de087748fe17275177c30c9786
https://escholarship.org/uc/item/4xg6h18t
https://escholarship.org/uc/item/4xg6h18t
Autor:
Kerry Bean, Harry Moore, Peter W. Andrews, Miguel A. Juárez, Paul J. Gokhale, Mark Wheeler, Ivana Barbaric, Thomas F. Allison, Steve Williams, Adam J. Hirst, Duncan Baker
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 7, Iss 5, Pp 998-1012 (2016)
Stem Cell Reports, Vol 7, Iss 5, Pp 998-1012 (2016)
Summary Genetic changes in human pluripotent stem cells (hPSCs) gained during culture can confound experimental results and potentially jeopardize the outcome of clinical therapies. Particularly common changes in hPSCs are trisomies of chromosomes 1,
Autor:
Thomas F. Allison, Jessie E. Buth, Simon Mitchell, Istvan Mody, William E. Lowry, Kathrin Plath, Jack M. Parent, Osvaldo A. Miranda, Arinnae Kurdian, Michael J. Gandal, Isabella Ferando, Ranmal A. Samarasinghe, Peyman Golshani, Namie N. Fotion, Bennett G. Novitch, Momoko Watanabe
Brain organoids represent a powerful tool for the study of human neurological diseases, particularly those impacting brain growth and structure. However, many diseases manifest with clear evidence of physiological and network abnormality in the absen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96ccef136463f73192e3bfa28d309e0
https://doi.org/10.1101/820183
https://doi.org/10.1101/820183
Autor:
William E. Lowry, Thomas F. Allison
Publikováno v:
Nature biomedical engineering. 1(10)
The genetic, epigenetic and transcriptomic profiles of human induced pluripotent stem cells are shaped by the reprogramming route.
Publikováno v:
Biochemical and biophysical research communications. 473(3)
Synthetic mRNA transfection enables efficient and controlled gene expression in human cells, without genome integrations. Further, modifications to the mRNA and transfection protocol now allow for repeated transfection and long-term gene expression o
Autor:
Shan Sabri, Kathrin Plath, James O.S. Hackland, Paul J. Gokhale, Peter W. Andrews, Mark Jones, Andrew J.H. Smith, Ivana Barbaric, Daniel Coca, Veronica Biga, Konstantinos Anastassiadis, Thomas F. Allison, Justin Langerman, Jackie Sloane-Stanley, Dylan Stavish
Publikováno v:
Stem Cell Reports
Stem cell reports, vol 10, iss 6
Allison, T F, Smith, A J H, Anastassiadis, K, Sloane-Stanley, J, Biga, V, Stavish, D, Hackland, J, Sabri, S, Langerman, J, Jones, M, Plath, K, Coca, D, Barbaric, I, Gokhale, P & Andrews, P W 2018, ' Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells ', Stem Cell Reports, vol. 10, no. 6, pp. 1895-1907 . https://doi.org/10.1016/j.stemcr.2018.04.015
Stem cell reports, vol 10, iss 6
Allison, T F, Smith, A J H, Anastassiadis, K, Sloane-Stanley, J, Biga, V, Stavish, D, Hackland, J, Sabri, S, Langerman, J, Jones, M, Plath, K, Coca, D, Barbaric, I, Gokhale, P & Andrews, P W 2018, ' Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells ', Stem Cell Reports, vol. 10, no. 6, pp. 1895-1907 . https://doi.org/10.1016/j.stemcr.2018.04.015
Summary Human embryonic stem cells (hESCs) display substantial heterogeneity in gene expression, implying the existence of discrete substates within the stem cell compartment. To determine whether these substates impact fate decisions of hESCs we use
Autor:
Barry Sampson, Simon Grant, Nicholas D. Allen, C. Patrick Case, Anna J. Jones, Sharan Athwal, Thomas F. Allison, Paul J. Gokhale, Peter W. Andrews
Publikováno v:
Jones, A J, Gokhale, P J, Allison, T F, Sampson, B, Athwal, S, Grant, S R, Andrews, P W, Allen, N D & Case, C P 2015, ' Evidence for bystander signalling between human trophoblast cells and human embryonic stem cells ', Scientific Reports, vol. 5, 11694 . https://doi.org/10.1038/srep11694
Scientific Reports
Scientific Reports
Maternal exposure during pregnancy to toxins can occasionally lead to miscarriage and malformation. It is currently thought that toxins pass through the placental barrier, albeit bi-layered in the first trimester and damage the fetus directly, albeit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4152736df7ff387f146fd460eb4364d8
http://hdl.handle.net/10044/1/57043
http://hdl.handle.net/10044/1/57043