Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thomas F Wunderlich"'
Autor:
Vera Lepperhof, Olga Polchynski, Klaus Kruttwig, Chantal Brüggemann, Klaus Neef, Florian Drey, Yunjie Zheng, Justus P Ackermann, Yeong-Hoon Choi, Thomas F Wunderlich, Mathias Hoehn, Jürgen Hescheler, Tomo Sarić
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107363 (2014)
Cell loss after transplantation is a major limitation for cell replacement approaches in regenerative medicine. To assess the survival kinetics of induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CM) we generated transgenic murine iPSC li
Externí odkaz:
https://doaj.org/article/9ff27e4f4b44467a8eb11df3e28fda8f
Autor:
Linda Engström Ruud, Ferran Font-Gironès, Joanna Zajdel, Lara Kern, Júlia Teixidor-Deulofeu, Louise Mannerås-Holm, Alba Carreras, Barbara Becattini, Andreas Björefeldt, Eric Hanse, Henning Fenselau, Giovanni Solinas, Jens C. Brüning, Thomas F. Wunderlich, Fredrik Bäckhed, Johan Ruud
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113960- (2024)
Summary: GFRAL-expressing neurons actuate aversion and nausea, are targets for obesity treatment, and may mediate metformin effects by long-term GDF15-GFRAL agonism. Whether GFRAL+ neurons acutely regulate glucose and energy homeostasis is, however,
Externí odkaz:
https://doaj.org/article/aa3d323435254270b9519bdc32c22457
Autor:
Edmund Neugebauer, Hossein Baharvand, Angelika Lampert, Stefan Herms, Nora Prochnow, Tomo Saric, Marek Molcanyi, Marco Timmer, Aiden Haghikia, Justus P. Ackermann, Jürgen Hescheler, Narges Zare Mehrjardi, Thomas F. Wunderlich, Firuze Fulya Hatay, Stefanie Heilmann-Heimbach, Ebrahim Shahbazi
Publikováno v:
Cell Proliferation
Cell proliferation 53(10), e12892 (2020). doi:10.1111/cpr.12892
Cell proliferation 53(10), e12892 (2020). doi:10.1111/cpr.12892
Objectives Genetic engineering of human‐induced pluripotent stem cell‐derived neural stem cells (hiPSC‐NSC) may increase the risk of genomic aberrations. Therefore, we asked whether genetic modification of hiPSC‐NSCs exacerbates chromosomal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fc5593418e34772e85443a0cb6ded8
Trans-presentation of interleukin-6 by dendritic cells is required for priming pathogenic TH17 cells
Autor:
Sylvia, Heink, Nir, Yogev, Christoph, Garbers, Marina, Herwerth, Lilian, Aly, Christiane, Gasperi, Veronika, Husterer, Andrew L, Croxford, Katja, Möller-Hackbarth, Harald S, Bartsch, Karl, Sotlar, Stefan, Krebs, Tommy, Regen, Helmut, Blum, Bernhard, Hemmer, Thomas, Misgeld, Thomas F, Wunderlich, Juan, Hidalgo, Mohamed, Oukka, Stefan, Rose-John, Marc, Schmidt-Supprian, Ari, Waisman, Thomas, Korn
Publikováno v:
Nature immunology
The cellular sources of interleukin-6 (IL-6) that are relevant for the differentiation of TH17 cells remain unclear. Here, we used a novel strategy of IL-6 conditional deletion of distinct IL-6-producing cell types to show that Sirpα+ dendritic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a0ec7eacd03c7d8fb5b8f980b9fcfceb
http://europepmc.org/articles/PMC5164931
http://europepmc.org/articles/PMC5164931
Autor:
Anja Hafemann, Bo Hu, Eran Elinav, Liming Hao, Samuel Huber, Till Strowig, Richard A. Flavell, Stephanie C. Eisenbarth, Thomas F. Wunderlich, Chengcheng Jin, Claudia M. Wunderlich
Publikováno v:
Proceedings of the National Academy of Sciences. 110:9862-9867
The microbiota is pivotal in the pathogenesis of inflammatory bowel disease (IBD)-associated inflammation-induced colorectal cancer (CRC), yet mechanisms for these effects remain poorly characterized. Here, we demonstrate that aberrant inflammasome-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52124ac65470e703b4e8a4ad190a272
https://doi.org/10.1073/pnas.1307575110
https://doi.org/10.1073/pnas.1307575110
Autor:
Bastian Ackermann, Janine Milbradt, Rocío Tejero, Thomas F. Wunderlich, Miriam Jakubik, Anke Borgmann, Julia Schreml, Seyyed Mohsen Hosseini Barkooie, Sandra Kröber, Miriam Peters, Lucia Tabares, Brunhilde Wirth, Markus Riessland, Laura Torres-Benito
Publikováno v:
Human Molecular Genetics. 22:1328-1347
F-actin bundling plastin 3 (PLS3) is a fully protective modifier of the neuromuscular disease spinal muscular atrophy (SMA), the most common genetic cause of infant death. The generation of a conditional PLS3-over-expressing mouse and its breeding in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e589997583e0252faff6ff775c64c0
https://doi.org/10.1093/hmg/dds540
https://doi.org/10.1093/hmg/dds540
Autor:
Michael Schramm, Vladimir Tchikov, Hamid Kashkar, Katja Wiegmann, Martin Krönke, Olaf Utermöhlen, Oleg Krut, Stefan Schütze, Benjamin Yazdanpanah, Carola Pongratz, Jens C. Brüning, André Kleinridders, Thomas F. Wunderlich
Publikováno v:
Nature. 460:1159-1163
Riboflavin kinase has been identified as a novel interacting partner for the death domain of receptor-1 for tumour necrosis factor (TNF-R1). It is required to recruit to and functionally couple p22phox to TNF-R1. As p22phox is the catalytic subunit o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2048121b50d99add006dbbb2fad626
https://doi.org/10.1038/nature08206
https://doi.org/10.1038/nature08206
Autor:
Matthias Kern, Nora Klöting, Matthias Blüher, Karen Ruschke, Jens C. Brüning, Thomas F. Wunderlich, Wilhelm Krone, Linda Koch
Publikováno v:
Diabetes
OBJECTIVE—IGF-1 and the IGF-1 receptor (IGF-1R) have been implicated in the regulation of adipocyte differentiation and lipid accumulation in vitro. RESEARCH DESIGN AND METHODS—To investigate the role of IGF-1 receptor in vivo, we have inactivate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8298bc86396a19c987c926af181e33
http://europepmc.org/articles/PMC2494689
http://europepmc.org/articles/PMC2494689
Publikováno v:
Deutsches Ärzteblatt Online.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e20f03d0968546119a9418d241c3db70
https://doi.org/10.3238/personko.2015.09.25.08
https://doi.org/10.3238/personko.2015.09.25.08
Autor:
Tommy Regen, Stefan Krebs, Thomas Korn, Sylvia Heink, Marina Herwerth, Andrew L. Croxford, Mohamed Oukka, Christoph Garbers, Karl Sotlar, Nir Yogev, Marc Schmidt-Supprian, Katja Möller-Hackbarth, Ari Waisman, Thomas Misgeld, Bernhard Hemmer, Veronika Husterer, Harald Bartsch, Lilian Aly, Juan Hidalgo, Thomas F. Wunderlich, Christiane Gasperi, Helmut Blum, Stefan Rose-John
Publikováno v:
Nature Immunology. 18:474-474
Nat. Immunol. 18, 74–85 (2017); published online 28 November 2016; corrected after print 23 January 2017 In the version of this article initially published, the label for third bar from the left in Figure 4f ('Anti-IL-6α') was incorrect; the corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3768303767607edac34cf61dfbd434fa
https://doi.org/10.1038/ni0417-474b
https://doi.org/10.1038/ni0417-474b