Zobrazeno 1 - 10
of 364
pro vyhledávání: '"Thomas F Schulz"'
Autor:
Peter Naniima, Eleonora Naimo, Sandra Koch, Ute Curth, Khaled R Alkharsah, Luisa J Ströh, Anne Binz, Jan-Marc Beneke, Benjamin Vollmer, Heike Böning, Eva Maria Borst, Prashant Desai, Jens Bohne, Martin Messerle, Rudolf Bauerfeind, Pierre Legrand, Beate Sodeik, Thomas F Schulz, Thomas Krey
Publikováno v:
PLoS Biology, Vol 19, Iss 11, p e3001423 (2021)
Herpesviruses cause severe diseases particularly in immunocompromised patients. Both genome packaging and release from the capsid require a unique portal channel occupying one of the 12 capsid vertices. Here, we report the 2.6 Å crystal structure of
Externí odkaz:
https://doaj.org/article/8f63efd205494ed79667519f4184774d
Autor:
Naira Samarina, George Ssebyatika, Tanvi Tikla, Ja-Yun Waldmann, Bizunesh Abere, Vittoria Nanna, Michelangelo Marasco, Teresa Carlomagno, Thomas Krey, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009635 (2021)
Kaposi Sarcoma-associated herpesvirus (KSHV) causes three human malignancies, Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and the plasma cell variant of multicentric Castleman's Disease (MCD), as well as an inflammatory cytokine syndrome (KI
Externí odkaz:
https://doaj.org/article/5bd22e854467486fb7a9d993ffd4e8b5
Autor:
Sandra Koch, Modester Damas, Anika Freise, Elias Hage, Akshay Dhingra, Jessica Rückert, Antonio Gallo, Elisabeth Kremmer, Werner Tegge, Mark Brönstrup, Wolfram Brune, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007743 (2019)
Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8) belongs to the subfamily of Gammaherpesvirinae and is the etiological agent of Kaposi's sarcoma as well as of two lymphoproliferative diseases: primary effusion lymphoma and multicen
Externí odkaz:
https://doaj.org/article/34c5f2e8d0464d74b002d78cb67c85a2
Autor:
Bizunesh Abere, Tamrat M Mamo, Silke Hartmann, Naira Samarina, Elias Hage, Jessica Rückert, Sven-Kevin Hotop, Guntram Büsche, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006639 (2017)
Kaposi's sarcoma-associated herpesvirus (KSHV) is the infectious cause of the highly vascularized tumor Kaposi's sarcoma (KS), which is characterized by proliferating spindle cells of endothelial origin, extensive neo-angiogenesis and inflammatory in
Externí odkaz:
https://doaj.org/article/8b0f53f027334d17a85522dc38174863
Autor:
Jasmin Zischke, Panagiota Mamareli, Claudia Pokoyski, Ildar Gabaev, Sabine Buyny, Roland Jacobs, Christine S Falk, Matthias Lochner, Tim Sparwasser, Thomas F Schulz, Penelope C Kay-Fedorov
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006454 (2017)
Human Cytomegalovirus (HCMV) is a widespread pathogen, infection with which can cause severe disease for immunocompromised individuals. The complex changes wrought on the host's immune system during both productive and latent HCMV infection are well
Externí odkaz:
https://doaj.org/article/89876fd1abc04f9bbd1d91407395d7a5
Autor:
Víctor González-Motos, Carina Jürgens, Birgit Ritter, Kai A Kropp, Verónica Durán, Olav Larsen, Anne Binz, Werner J D Ouwendijk, Tihana Lenac Rovis, Stipan Jonjic, Georges M G M Verjans, Beate Sodeik, Thomas Krey, Rudolf Bauerfeind, Thomas F Schulz, Benedikt B Kaufer, Ulrich Kalinke, Amanda E I Proudfoot, Mette M Rosenkilde, Abel Viejo-Borbolla
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006346 (2017)
Varicella zoster virus (VZV) is a highly prevalent human pathogen that establishes latency in neurons of the peripheral nervous system. Primary infection causes varicella whereas reactivation results in zoster, which is often followed by chronic pain
Externí odkaz:
https://doaj.org/article/67a7306e93734a6fb0c1a6b9d1cccf9f
Autor:
Giuseppe Mariggiò, Sandra Koch, Guigen Zhang, Magdalena Weidner-Glunde, Jessica Rückert, Semra Kati, Susann Santag, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006335 (2017)
Kaposi Sarcoma Herpesvirus (KSHV), a γ2-herpesvirus and class 1 carcinogen, is responsible for at least three human malignancies: Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and Multicentric Castleman's Disease (MCD). Its major nuclear late
Externí odkaz:
https://doaj.org/article/8e2d1392c13f49ba96f244309937f53b
Autor:
Javier Botey-Bataller, Hedwig D. Vrijmoeth, Jeanine Ursinus, Bart-Jan Kullberg, Cees C. van den Wijngaard, Hadewych ter Hofstede, Ahmed Alaswad, Manoj K. Gupta, Lennart M. Roesner, Jochen Huehn, Thomas Werfel, Thomas F. Schulz, Cheng-Jian Xu, Mihai G. Netea, Joppe W. Hovius, Leo A. B. Joosten, Yang Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The incidence of Lyme borreliosis has risen, accompanied by persistent symptoms. The innate immune system and related cytokines are crucial in the host response and symptom development. We characterized cytokine production capacity before an
Externí odkaz:
https://doaj.org/article/e3dcc9f358504f8d8994380adb860b5e
Autor:
Silvia Gramolelli, Magdalena Weidner-Glunde, Bizunesh Abere, Abel Viejo-Borbolla, Kiran Bala, Jessica Rückert, Elisabeth Kremmer, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005105 (2015)
Kaposi's sarcoma (KS), caused by Kaposi's sarcoma herpesvirus (KSHV), is a highly vascularised tumour of endothelial origin. KSHV infected endothelial cells show increased invasiveness and angiogenesis. Here, we report that the KSHV K15 protein, whic
Externí odkaz:
https://doaj.org/article/83ed447019c843229b6c8cce9166594e
Autor:
Svenja M. Sake, Xiaoyu Zhang, Manoj Kumar Rajak, Melanie Urbanek-Quaing, Arnaud Carpentier, Antonia P. Gunesch, Christina Grethe, Alina Matthaei, Jessica Rückert, Marie Galloux, Thibaut Larcher, Ronan Le Goffic, Fortune Hontonnou, Arnab K. Chatterjee, Kristen Johnson, Kaycie Morwood, Katharina Rox, Walid A. M. Elgaher, Jiabin Huang, Martin Wetzke, Gesine Hansen, Nicole Fischer, Jean-Francois Eléouët, Marie-Anne Rameix-Welti, Anna K. H. Hirsch, Elisabeth Herold, Martin Empting, Chris Lauber, Thomas F. Schulz, Thomas Krey, Sibylle Haid, Thomas Pietschmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infection in infants, older adults and the immunocompromised. Effective directly acting antivirals are not yet available for clinical use. To address this,
Externí odkaz:
https://doaj.org/article/66d08a2bbc3740f4a9e811166d229bd4