Výsledky vyhledávání - "Thomas Eichberger"

Akademický článek

Hedgehog/GLI signaling activates suppressor of cytokine signaling 1 (SOCS1) in epidermal and neural tumor cells.

Autor: Sandra Laner-Plamberger, Florian Wolff, Alexandra Kaser-Eichberger, Stefan Swierczynski, Cornelia Hauser-Kronberger, Anna-Maria Frischauf, Thomas Eichberger

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e75317 (2013)

Sustained hedgehog (Hh) signaling mediated by the GLI transcription factors is implicated in many types of cancer. Identification of Hh/GLI target genes modulating the activity of other pathways involved in tumor development promise to open new ways

Externí odkaz: https://doaj.org/article/4e6227ef5e3143168574a7542c12a612

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Data from Activation of the BCL2 Promoter in Response to Hedgehog/GLI Signal Transduction Is Predominantly Mediated by GLI2

Autor: Fritz Aberger, Anna-Maria Frischauf, Cornelia Hauser-Kronberger, Harald Esterbauer, Michael P. Philpott, Graham W. Neill, Thomas Eichberger, Harald Schnidar, Maria Kasper, Gerhard Regl

Aberrant activation of the Hedgehog (HH)/GLI signaling pathway has been implicated in the development of basal cell carcinoma (BCC). The zinc finger transcription factors GLI1 and GLI2 are considered mediators of the HH signal in epidermal cells, alt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0f176b397fe87c15a0214168f39918
https://doi.org/10.1158/0008-5472.c.6493830.v1

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Cooperation between GLI and JUN enhances transcription of JUN and selected GLI target genes

Autor: Cornelia Hauser-Kronberger, Annemarie Frischauf, Thomas Eichberger, Alexandra Kaser, M Paulischta, Sandra Laner-Plamberger

Publikováno v: Oncogene. 28:1639-1651

Sustained Hedgehog (HH) signaling is implicated in basal cell carcinoma of the skin and other types of cancer. Here we show that GLI1 and GLI2, the main transcriptional activators of the HH pathway, directly regulate expression of the activator prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ceff983bc2051aaf7b804a9517cb55
https://doi.org/10.1038/onc.2009.10

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GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells

Autor: Fritz Aberger, Martina Winklmayr, Claudia Pixner, Anna-Maria Frischauf, Carmen Schmid, Alexandra Kaser, Cornelia Hauser-Kronberger, Stefan Klingler, Thomas Eichberger

Publikováno v: Journal of Biological Chemistry. 283:12426-12437

Hedgehog (HH) signaling in the epidermis is primarily mediated by the zinc finger transcription factors GLI1 and GLI2. Exquisite regulation of HH/GLI signaling is crucial for proper specification of the epidermal lineage and development of its deriva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcc0809d6d19df6dff57fdf01665151
https://doi.org/10.1074/jbc.m707117200

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Activation of the BCL2 Promoter in Response to Hedgehog/GLI Signal Transduction Is Predominantly Mediated by GLI2

Autor: Fritz Aberger, Gerhard Regl, Thomas Eichberger, Graham W. Neill, Cornelia Hauser-Kronberger, Harald Schnidar, Harald Esterbauer, Maria Kasper, Anna-Maria Frischauf, Michael P. Philpott

Publikováno v: Cancer Research. 64:7724-7731

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa353fcbeaec90b7009d6f85b98003e3
https://doi.org/10.1158/0008-5472.can-04-1085

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GLI2 Is Expressed in Normal Human Epidermis and BCC and Induces GLI1 Expression by Binding to its Promoter

Autor: Gerhard Regl, Thomas Eichberger, Michael P. Philpott, Graham W. Neill, Fritz Aberger, Mohammed S. Ikram, Anthony G. Quinn, Anna-Maria Frischauf

Publikováno v: Journal of Investigative Dermatology. 122:1503-1509

Sonic hedgehog (Shh) binds to its receptor patched (PTCH), leading to the activation and repression of target genes via the GLI family of zinc-finger transcription factors. Deregulation of the Shh pathway is associated with basal cell carcinoma (BCC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ca107bcfe9c796acc191ed5b091c21
https://doi.org/10.1111/j.0022-202x.2004.22612.x

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The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells

Autor: Harald Schnidar, Fritz Aberger, Mohammed S. Ikram, Thomas Eichberger, Gerhard Regl, Graham W. Neill, Maria Kasper, Michael P. Philpott, Anthony G. Quinn, Anna-Maria Frischauf

Publikováno v: Oncogene. 23:1263-1274

In stratified epidermis, activation of the Hh/Gli signal transduction pathway has been implicated in the control of cell proliferation and tumorigenesis. The zinc-finger transcription factor Gli2 has been identified as critical mediator of the Hh sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40fd3673af595a08a963977e3fa88353
https://doi.org/10.1038/sj.onc.1207240

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Sporulation-specific expression of the yeast DIT1/DIT2 promoter is controlled by a newly identified repressor element and the short form of Rim101p

Autor: Roland Schricker, Edith Bogengruber, Peter Briza, Michael Breitenbach, Ian W. Dawes, Thomas Eichberger

Publikováno v: European Journal of Biochemistry. 258:430-436

Expression of the yeast genes DIT1 and DIT2 is confined to mid/late sporulation. Transcription of these two divergently arranged genes is controlled by a common 900-bp intergenic region. Random mutagenesis of this promoter and tests with appropriate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d3652519e2c87b3131e817c7e24a51
https://doi.org/10.1046/j.1432-1327.1998.2580430.x

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