Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thomas Edward Mabry"'
Autor:
Debra Luffer-Atlas, Colin F. Green, M. Jane Luo, Jennifer Leohr, Jeffrey G. Suico, Thomas Edward Mabry, David J. DeBrota
Publikováno v:
The Journal of Clinical Pharmacology. 58:412-424
The safety, pharmacokinetic, and pharmacodynamic effects of LY2584702, a selective inhibitor for p70 S6 serine/threonine protein kinase-1, were evaluated in healthy dyslipidemic volunteers. LY2584702 was tolerated well as a monotherapy and dose-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efe164ad75e30708aca3feb5690114f
https://doi.org/10.1002/jcph.1032
https://doi.org/10.1002/jcph.1032
Autor:
Xiaohong Yu, Debra Luffer-Atlas, Paul L. Milligan, M. Jane Luo, Najia Jin, Asim Bikash Dey, Adrian J. Fretland, Jennifer Leohr, Charles Reidy, Mark C. Kowala, Yuke Zhang, Thomas B. Estridge, Maryalice Hartley, Thomas Edward Mabry
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 362(1)
LY2584702 is an inhibitor of p70 S6 kinase-1 previously developed for the treatment of cancer. In two phase 1 trials in oncology patients, significant reductions of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42f17ddec7ab641708896cbc8170e60
https://pubmed.ncbi.nlm.nih.gov/28465372
https://pubmed.ncbi.nlm.nih.gov/28465372
Autor:
Richard W. Zink, John G. Luz, Xiaoping Ruan, Milan Maletic, Thomas Edward Mabry, Matthew W. Carson, David K. Clawson, Nancy June Snyder, Michael J. Coghlan, A. Pustilnik, Chen Suen, Mary D. Adrian, Harlan W. Cole, Chahrzad Montrose, Daniel Timothy Kohlman, Brad Condon, Christine C. Cheng
Publikováno v:
Journal of medicinal chemistry. 57(3)
The structural basis of the pharmacology enabling the use of glucocorticoids as reliable treatments for inflammation and autoimmune diseases has been augmented with a new group of glucocorticoid receptor (GR) ligands. Compound 10, the archetype of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e0493a3fab96dd384d92ca38639224
https://pubmed.ncbi.nlm.nih.gov/24446728
https://pubmed.ncbi.nlm.nih.gov/24446728
Autor:
Jay S. Tung, Michael A. Pleiss, Albert W. Garofalo, Erich Goldbach, Cheryl A. Bales, David W. G. Wone, James E. Audia, Stephen Sohn, Darren B. Dressen, Thomas Edward Mabry, Angela Phuc, Nissen Jeffrey S, Thorsett Eugene D, Folmer Beverly K, Jing Wu, Harry F. Dovey, Ashley C. Guinn, Lee H. Latimer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:3051-3053
Potent, small molecule A beta inhibitors have been prepared that incorporate an alanine core bracketed by an N-terminal arylacetyl group and various C-terminal amino alcohols. The compounds exhibit stereospecific inhibition as demonstrated in an in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54cab507103921c3382fac6a78953b0
https://doi.org/10.1016/s0960-894x(02)00684-4
https://doi.org/10.1016/s0960-894x(02)00684-4
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
[52727-95-4] C9H9BrO2 (MW 229.07) InChI = 1/C9H9BrO2/c1-7(11)12-9-4-2-8(6-10)3-5-9/h2-5H,6H2,1H3 InChIKey = MEUWUBXEOFFOOX-UHFFFAOYAW (reagent used as a hydroxyl-protecting group and a benzylating agent) Alternate Name: 4-acetoxybenzyl bromide, 4-(ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1572d626e8fbd82cba65396564fff70
https://doi.org/10.1002/047084289x.rn00323.pub2
https://doi.org/10.1002/047084289x.rn00323.pub2
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 29:583-589
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eebf3accb1fbf82974e5efe45dc891a9
https://doi.org/10.1002/jlcr.2580290510
https://doi.org/10.1002/jlcr.2580290510
Autor:
Charles David Jones, Larry C. Blaszczak, Mary Elizabeth Goettel, Tulio Suarez, V. Srivatsan, Thomas Alan Crowell, Thomas Edward Mabry, Peter C. Ruenitz
Publikováno v:
Journal of medicinal chemistry. 35(5)
Benzothiophenes 3 and 4, derived from the acrylophenone antiestrogen trioxifene (2), are characterized by high estrogen receptor (ER) affinity and low residual estrogenicity compared to tamoxifen (1a). In order to characterize further the growth supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa6dabf8a6857147693fc1f28c5d873
https://pubmed.ncbi.nlm.nih.gov/1548683
https://pubmed.ncbi.nlm.nih.gov/1548683
Autor:
Patrick J. C. May, Bruce D. Gitter, Tinggui Yin, Thomas Edward Mabry, Paul A. Hyslop, Mark H. Bender, Donna K. Dieckman, James E. Audia, Nissen Jeffrey S, Weiying Li, Dan L. Czilli, Mcclure Don B, Leonard N. Boggs, Edward M. Johnstone, Sheila P. Little
Publikováno v:
Neurobiology of Aging. 25:S571
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b984b8aa0622894a79080f7b45987199
https://doi.org/10.1016/s0197-4580(04)81897-9
https://doi.org/10.1016/s0197-4580(04)81897-9
Autor:
Leonard N. Boggs, Bruce D. Gitter, Nissen Jeffrey S, Daniel L. Czilli, Thomas Edward Mabry, Paul A. Hyslop, Yuan Su, James E. Audia, Binhui Ni, Patrick J. C. May, Weiying Li, Mark H. Bender, Kimberly S. Fuson
Publikováno v:
Neurobiology of Aging. 25:S218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb2e69d17213abf3579f34de898622c6
https://doi.org/10.1016/s0197-4580(04)80731-0
https://doi.org/10.1016/s0197-4580(04)80731-0
Autor:
Jeffrey W. Cramer, David O. Calligaro, James E. Audia, Bruce D. Gitter, Patrick J. C. May, Carl L. McMillian, Paul A. Hyslop, Carlos O. Garner, Jeffry S. Nissen, Mark H. Bender, Warren J. Porter, Thomas Edward Mabry
Publikováno v:
Neurobiology of Aging. 25:S147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b706945227eb7ff89e844bd9a189e688
https://doi.org/10.1016/s0197-4580(04)80493-7
https://doi.org/10.1016/s0197-4580(04)80493-7