Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Thomas Edlund"'
Autor:
Man K.S. Lee, Olivia D. Cooney, Xuzhu Lin, Shaktypreya Nadarajah, Dragana Dragoljevic, Kevin Huynh, Danise-Ann Onda, Sandra Galic, Peter J. Meikle, Thomas Edlund, Morgan D. Fullerton, Bruce E. Kemp, Andrew J. Murphy, Kim Loh
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101514- (2022)
Objectives: Dysregulation of cholesterol metabolism in the liver and hematopoietic stem and progenitor cells (HSPCs) promotes atherosclerosis development. Previously, it has been shown that HMG-CoA-Reductase (HMGCR), the rate-limiting enzyme in the m
Externí odkaz:
https://doaj.org/article/8e3ca735c9ca4ee3934879d9b15a6a5b
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1625 (2008)
The formation of functional neural circuits that process sensory information requires coordinated development of the central and peripheral nervous systems derived from neural plate and neural plate border cells, respectively. Neural plate, neural cr
Externí odkaz:
https://doaj.org/article/5da0d1a05fda408487e70d87fc25ab5b
Publikováno v:
PLoS Biology, Vol 4, Iss 8, p e252 (2006)
The link between extrinsic signaling, progenitor cell specification and neuronal subtype identity is central to the developmental organization of the vertebrate central nervous system. In the hindbrain and spinal cord, distinctions in the rostrocauda
Externí odkaz:
https://doaj.org/article/976879a13e8c4f9db77108b6ca2a46c5
Autor:
Pär Steneberg, Jurate Straseviciene, Emma Lindahl, Thomas Edlund, Ingela Lundberg, Eva Berggren, Ingela Bergqvist, Ulf Dahl, Helena Edlund, Elisabet Kjellkvist, Jacob Westman, Fredrik Backlund, Madelene Ericsson, Emmelie Lidh, Björn Eriksson, Kajsa Linde
AMPK activated protein kinase (AMPK), a master regulator of energy homeostasis, is activated in response to an energy shortage imposed by physical activity and caloric restriction. We here report on the identification of PAN-AMPK activator O304, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98ea9240feacb19baac17823628884d
https://europepmc.org/articles/PMC6124394/
https://europepmc.org/articles/PMC6124394/
Publikováno v:
Development. 136:73-83
The non-neural ectoderm is divided into neural plate border and epidermal cells. At early blastula stages, Wnt and BMP signals interact to induce epidermal fate, but when and how cells initially acquire neural plate border fate remains poorly defined
Publikováno v:
Developmental Cell. 13:141-149
SummarySpatial gradients of extracellular signals are implicated in the patterning of many different tissues. Much less is known, however, about how differences in time of exposure of progenitor cells to patterning signals can influence different cel
Autor:
Jorge B. Aquino, Thomas Edlund, Martin Koltzenburg, Patrik Ernfors, Marcelo J. Villar, Jens Hjerling-Leffler
Publikováno v:
Experimental Neurology. 198:438-449
Boundary cap cells can generate neurons as well as peripheral glia during embryonic development (Maro, G.S., Vermeren, M., Voiculescu, O., Melton, L., Cohen, J., Charnay, P., Topilko, P., 2004. Neural crest boundary cap cells constitute a source of n
Convergent Wnt and FGF signaling at the gastrula stage induce the formation of the isthmic organizer
Publikováno v:
Mechanisms of Development. 123:166-176
The development of the vertebrate brain depends on the formation of local organizing centres within the neural tube that express secreted signals that refine local neural progenitor identity. The isthmic organizer (IsO) forms at the isthmic constrict
Publikováno v:
Nature Neuroscience. 6:701-707
Dorsoventral patterning of the telencephalon is established early in forebrain development and underlies many of the regional subdivisions that are critical to the later organization of neural circuits in the cerebral cortex and basal ganglia. Sonic
Publikováno v:
Nature Neuroscience. 5:525-532
Early in differentiation, all neural cells have a rostral character. Only later do posteriorly positioned neural cells acquire characteristics of caudal forebrain, midbrain and hindbrain cells. Caudalization of neural tissue in the chick embryo appar