Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Thomas EF"'
Autor:
Xinyu Deng, Yubing Li, Yuan Chen, Qichao Hu, Wenwen Zhang, Lisheng Chen, Xiaohua Lu, Jinhao Zeng, Xiao Ma, Thomas Efferth
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-23 (2024)
Abstract Background Drug-induced liver injury (DILI) is gradually becoming a common global problem that causes acute liver failure, especially in acute hepatic damage caused by acetaminophen (APAP). Paeoniflorin (PF) has a wide range of therapeutic e
Externí odkaz:
https://doaj.org/article/f62d5232b16349bfbc6031cd8f01db0c
Autor:
Hisham Al-Matubsi, Luay Rashan, Walid Aburayyan, Othman Al Hanbali, Duaa Abuarqoub, Thomas Efferth
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 15, Iss 4, Pp 101014- (2024)
Background: Diabetes is a metabolic disorder requiring the administration of insulin or other oral hypoglycemic medicines. Although metformin is a popular prescription for type 2 diabetes, long-term use of chemotherapy-based diabetes medications can
Externí odkaz:
https://doaj.org/article/c16f7bf6c9fd4e02aa601d8a894d8f97
Autor:
Mead, Simon, Poulter, Mark, Uphill, James, Beck, John, Whitfield, Jerome, Webb, Thomas EF, Campbell, Tracy, Adamson, Gary, Deriziotis, Pelagia, Tabrizi, Sarah J, Hummerich, Holger, Verzilli, Claudio, Alpers, Michael P, Whittaker, John C, Collinge, John
Publikováno v:
In Lancet Neurology 2009 8(1):57-66
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116594- (2024)
Cholestatic liver disease (CLD) is a range of conditions caused by the accumulation of bile acids (BAs) or disruptions in bile flow, which can harm the liver and bile ducts. To investigate its pathogenesis and treatment, it is essential to establish
Externí odkaz:
https://doaj.org/article/399f4fe4019040daa78235ee15c77fc8
Autor:
Jiahui Ni, Lijie Zhang, Guize Feng, Weilian Bao, Yirui Wang, Yuran Huang, Tongqing Chen, Jieli Chen, Xinyue Cao, Keyuan You, Sheng Tan, Thomas Efferth, Hong Li, Bo Li, Xiaoyan Shen, Yan You
Publikováno v:
Pharmacological Research, Vol 202, Iss , Pp 107128- (2024)
The damage of integrated epithelial epithelium is a key pathogenic factor and closely associated with the recurrence of ulcerative colitis (UC). Here, we reported that vanillic acid (VA) exerted potent therapeutic effects on DSS-induced colitis by re
Externí odkaz:
https://doaj.org/article/8507d02c76c1467296f753688e1cd59d
Publikováno v:
Molecules, Vol 29, Iss 17, p 4031 (2024)
Ulcerative colitis (UC) is a typical inflammatory bowel disease (IBD), impairing the quality of life of patients. Dehydroevodiamine (DHE) is an active alkaloid isolated from Tetradium ruticarpum that exerts significant anti-inflammatory effects in ga
Externí odkaz:
https://doaj.org/article/a2143038085042b59b1c105c06b2294a
Autor:
Assia I. Drif, Rümeysa Yücer, Roxana Damiescu, Nadeen T. Ali, Tobias H. Abu Hagar, Bharati Avula, Ikhlas A. Khan, Thomas Efferth
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1484 (2024)
Background and aim: Chamomile tea, renowned for its exquisite taste, has been appreciated for centuries not only for its flavor but also for its myriad health benefits. In this study, we investigated the preventive potential of chamomile (Matricaria
Externí odkaz:
https://doaj.org/article/055dd89565ff4ab99408703981112cf5
Autor:
Valaire Y. Matieta, Armelle T. Mbaveng, Guy R. Sado Nouemsi, Simplice B. Tankeo, Gabriel T. Kamsu, Paul Nayim, Alain M. Lannang, İlhami Çelik, Thomas Efferth, Victor Kuete
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background Bauhinia thonningii is a plant traditionally used against many human diseases such as gastric ulcers, fever, inflammations, coughs, dysentery, diarrhea, and malaria. In the present investigation, the cytotoxicity of methanol extra
Externí odkaz:
https://doaj.org/article/8f2fc211f55b4423882413d7abd43f9d
Autor:
Ying-Lan Chen, Fan-Wei Lin, Kai-Tan Cheng, Chi-Hsin Chang, Sheng-Chi Hung, Thomas Efferth, Yet-Ran Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Proteolytic activation of cytokines regulates immunity in diverse organisms. In animals, cysteine-dependent aspartate-specific proteases (caspases) play central roles in cytokine maturation. Although the proteolytic production of peptide cyt
Externí odkaz:
https://doaj.org/article/5ae07089548c4bd6ae14ca845b9b26eb
Autor:
Fabian Bernhard Pallasch, Vera Freytag, Malte Kriegs, Dennis Gatzemeier, Thomas Mair, Hannah Voss, Kristoffer Riecken, Mona Dawood, Boris Fehse, Thomas Efferth, Hartmut Schlüter, Udo Schumacher
Publikováno v:
Cancers, Vol 16, Iss 12, p 2278 (2024)
Background: Remarkable differences exist in the outcome of systemic cancer therapies. Lymphomas and leukemias generally respond well to systemic chemotherapies, while solid cancers often fail. We engineered different human cancer cells lines to unifo
Externí odkaz:
https://doaj.org/article/12f69dbe38744863bb7847d33451fb58