Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Thomas E. Spires"'
Autor:
Raymond B. Birge, Thomas E. Spires, Michael Quigley, William C. Gause, Pankaj K. Mishra, Tessa Bergsbaken, Sergei V. Kotenko, Mariana S. De Lorenzo, Chan Gao, Michael Wichroski, Yun-juan Chang, Kevin C. Lahey, Canan Kasikara, Varsha Gadiyar, Dhriti Mehta, David Calianese, Ke Geng, Sushil Kumar, Viralkumar Davra
Figure S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c022c8f5090104975241f11d235eae
https://doi.org/10.1158/0008-5472.22427005
https://doi.org/10.1158/0008-5472.22427005
Autor:
Marco M. Gottardis, Robert Kramer, Gregory Vite, Shen-Jue Chen, Joseph Dinchuk, William R. Foster, Mark E. Salvati, Weifang Shan, Mary Obermeier, J. Suso Platero, Thomas E. Spires, Liang Schweizer, Cheryl A. Rizzo, Janet Dell-John, Mary Ellen Cvijic, Aaron Balog, Maria Jure-Kunkel, Ricardo M. Attar
Supplementary Table 1 from Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea96b450993c30817e08b09d67ecd09
https://doi.org/10.1158/0008-5472.22377966
https://doi.org/10.1158/0008-5472.22377966
Autor:
Marco M. Gottardis, Robert Kramer, Gregory Vite, Shen-Jue Chen, Joseph Dinchuk, William R. Foster, Mark E. Salvati, Weifang Shan, Mary Obermeier, J. Suso Platero, Thomas E. Spires, Liang Schweizer, Cheryl A. Rizzo, Janet Dell-John, Mary Ellen Cvijic, Aaron Balog, Maria Jure-Kunkel, Ricardo M. Attar
Supplementary Table 2 from Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77108c0dff54d0d9d17df83470660395
https://doi.org/10.1158/0008-5472.22377963.v1
https://doi.org/10.1158/0008-5472.22377963.v1
Autor:
Marco M. Gottardis, Robert Kramer, Gregory Vite, Shen-Jue Chen, Joseph Dinchuk, William R. Foster, Mark E. Salvati, Weifang Shan, Mary Obermeier, J. Suso Platero, Thomas E. Spires, Liang Schweizer, Cheryl A. Rizzo, Janet Dell-John, Mary Ellen Cvijic, Aaron Balog, Maria Jure-Kunkel, Ricardo M. Attar
Supplementary Figure and Table Legends 1-2 from Discovery of BMS-641988, a Novel and Potent Inhibitor of Androgen Receptor Signaling for the Treatment of Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c30c0ceeb3ee6de838292a026446d0
https://doi.org/10.1158/0008-5472.22377969
https://doi.org/10.1158/0008-5472.22377969
Autor:
Michael Basso, David A. Gordon, Julio A. Chirinos, Thomas P. Cappola, Zhaoqing Wang, Mary Ellen Cvijic, Dietmar A. Seiffert, Payman Zamani, Priyanka Bhattacharya, Melissa Yarde, Bruce D. Car, Stuart B. Prenner, Kenneth B. Margulies, Jason H. Moore, Zhuyin Li, Thomas E. Spires, Alena Orlenko, Anupam Kumar, Lei Zhao
Publikováno v:
Journal of the American College of Cardiology. 75:1281-1295
Background Better risk stratification strategies are needed to enhance clinical care and trial design in heart failure with preserved ejection fraction (HFpEF). Objectives The purpose of this study was to assess the value of a targeted plasma multi-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50844f066fc02776c67b16d6c5365949
https://doi.org/10.1016/j.jacc.2019.12.069
https://doi.org/10.1016/j.jacc.2019.12.069
Autor:
Mary Ellen Cvijic, Jeremy A. Mazurek, Melissa Yarde, Michael Basso, Julio A. Chirinos, Zhaoqing Wang, Stuart B. Prenner, Dietmar A. Seiffert, Zhuyin Li, Payman Zamani, Priyanka Bhattacharya, David A. Gordon, Thomas E. Spires, Lei Zhao, Anupam Kumar
Publikováno v:
The American Journal of Cardiology. 125:575-582
Little data are available regarding the determinants and prognostic significance of serum albumin in Heart Failure with Preserved Ejection Fraction (HFpEF). We sought to examine the phenotypic correlates of albumin and its independent prognostic impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c93cc6d728396c34f30e487beeaeeb
https://doi.org/10.1016/j.amjcard.2019.11.006
https://doi.org/10.1016/j.amjcard.2019.11.006
Autor:
Quynh Nhu Nguyen, James W. Welsh, Mauricio S. Caetano, Hari Menon, Hampartsoum B. Barsoumian, Jonathan E. Schoenhals, Chan Gao, Alexandra P. Cadena, Taylor R. Cushman, Ahmed I. Younes, Thomas E. Spires, Michael Quigley, Timothy P. Reilly, Ailin Li, Maria Angelica Cortez
Publikováno v:
Clin Cancer Res
Purpose: Radiotherapy (RT) traditionally has been used for local tumor control in the treatment of cancer. The recent discovery that radiotherapy can have anticancer effects on the immune system has led to recognition of its ability to sensitize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f89b86c5a7d0ef8f7d50f22b35eb6b
https://doi.org/10.1158/1078-0432.ccr-19-0795
https://doi.org/10.1158/1078-0432.ccr-19-0795
Autor:
Michael Wichroski, Lucia Suarez-Lopez, Raymond B. Birge, Canan Kasikara, Mariana S. De Lorenzo, Thomas E. Spires, Michael B. Yaffe, Viralkumar Davra, Ganapathy Sriram, Sergei V. Kotenko, Ke Geng, Michael Quigley, David Calianese
Publikováno v:
Cancer Research. 79:2669-2683
Tyro3, Axl, and Mertk (TAM) represent a family of homologous tyrosine kinase receptors known for their functional role in phosphatidylserine (PS)-dependent clearance of apoptotic cells and also for their immune modulatory functions in the resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698ce405abe2e33b3b44bd20fbfe1bbd
https://doi.org/10.1158/0008-5472.can-18-2614
https://doi.org/10.1158/0008-5472.can-18-2614
Autor:
Thomas E. Spires, Pankaj K. Mishra, Sergei V. Kotenko, Yun Juan Chang, Canan Kasikara, Sushil Kumar, Michael Wichroski, Kevin C. Lahey, Mariana S. De Lorenzo, David Calianese, Tessa Bergsbaken, Chan Gao, Ke Geng, Viralkumar Davra, Raymond B. Birge, Varsha Gadiyar, Dhriti Mehta, Michael Quigley, William C. Gause
Publikováno v:
Cancer research. 81(3)
Despite the promising clinical benefit of targeted and immune checkpoint blocking therapeutics, current strategies have limited success in breast cancer, indicating that additional inhibitory pathways are required to complement existing therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05ea023b2a7ab71922b907cd11e363d
https://pubmed.ncbi.nlm.nih.gov/33239426
https://pubmed.ncbi.nlm.nih.gov/33239426
Autor:
Gregory D. Vite, Paul A. Elzinga, David L. Gold, Cheryl A. Rizzo, Thomas E. Spires, Sophie Beyer, Vanessa M. Spires, Marco M. Gottardis, George L. Trainor, Aberra Fura, Audris Huang, Gordon Todderud, John A. Newitt, Lata Jayaraman, Aaron Balog, Andrew J. Tebben, Yongxin Zhu, Mary T. Obermeier, Goodenough Angela, Bethanne M. Warrack, Arthur M. Doweyko, Yi Fan
Publikováno v:
ACS Medicinal Chemistry Letters. 7:40-45
Efforts to identify a potent, reversible, nonsteroidal CYP17A1 lyase inhibitor with good selectivity over CYP17A1 hydroxylase and CYPs 11B1 and 21A2 for the treatment of castration-resistant prostate cancer (CRPC) culminated in the discovery of BMS-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d9351633fecd0f6648e90171669cc3
https://doi.org/10.1021/acsmedchemlett.5b00310
https://doi.org/10.1021/acsmedchemlett.5b00310