Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Thomas E. Morris"'
Autor:
Thu A. Doan, Tadg S. Forward, Johnathon B. Schafer, Erin D. Lucas, Ira Fleming, Aspen Uecker-Martin, Edgardo Ayala, Jenna J. Guthmiller, Jay R. Hesselberth, Thomas E. Morrison, Beth A. Jirón Tamburini
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Antigens from viruses or immunizations can persist or are archived in lymph node stromal cells such as lymphatic endothelial cells (LEC) and fibroblastic reticular cells (FRC). Here, we find that, during the time frame of antigen archiving,
Externí odkaz:
https://doaj.org/article/c51ada010dc34878b794df452efbd18b
Autor:
Peiqi Yin, Nicholas A. May, Laura Sandra Lello, Atef Fayed, M. Guston Parks, Adam M. Drobish, Sainan Wang, Meghan Andrews, Zachary Sticher, Alexander A. Kolykhalov, Michael G. Natchus, George R. Painter, Andres Merits, Margaret Kielian, Thomas E. Morrison
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Chikungunya virus (CHIKV) is an enveloped, positive-sense RNA virus that has re-emerged to cause millions of human infections worldwide. In humans, acute CHIKV infection causes fever and severe muscle and joint pain. Chronic and debilitating
Externí odkaz:
https://doaj.org/article/dfff5e12899b43dd9c8db8e7247e88db
Publikováno v:
Vaccines, Vol 12, Iss 11, p 1201 (2024)
The recent SARS-CoV-2 (COVID-19) pandemic exemplifies how newly emerging and reemerging viruses can quickly overwhelm and cripple global infrastructures. Coupled with synergistic factors such as increasing population densities, the constant and massi
Externí odkaz:
https://doaj.org/article/7e49fa4be0f44228a3dade85006b2ea5
Autor:
Autumn C. Holmes, Cormac J. Lucas, Morgan E. Brisse, Brian C. Ware, Heather D. Hickman, Thomas E. Morrison, Michael S. Diamond
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113876- (2024)
Summary: Alphaviruses are mosquito-transmitted pathogens that induce high levels of viremia, which facilitates dissemination and vector transmission. One prevailing paradigm is that, after skin inoculation, alphavirus-infected resident dendritic cell
Externí odkaz:
https://doaj.org/article/dd85bfbcd96b40e78b5375c2d78a42f8
Autor:
Stephanie E. Ander, Kathryn S. Carpentier, Wes Sanders, Cormac J. Lucas, Austin J. Jolly, Cydney N. Johnson, David W. Hawman, Mark T. Heise, Nathaniel J. Moorman, Thomas E. Morrison
Publikováno v:
Viruses, Vol 16, Iss 6, p 861 (2024)
We previously reported that deletion of a 44-nucleotide element in the 3′ untranslated region (UTR) of the Chikungunya virus (CHIKV) genome enhances the virulence of CHIKV infection in mice. Here, we find that while this 44-nucleotide deletion enha
Externí odkaz:
https://doaj.org/article/de9d1c236b594b4e9eb72f3e4301308c
Autor:
Petr Novotný, Fabian Toth, Tamas Visegrady, Angel Nunez Mencias, Donna N. Dillenberger, John C. Dayka, Jakob C. Lang, Volodymyr Paprotski, Thomas E. Morris, Ellen Carbarnes, Bill O'Farrell
Publikováno v:
IBM Journal of Research and Development. 62:4:1-4:11
Blockchain is a technology that has been available for several years and has already had several generations. Multiple implementations exist. In this paper, we describe how one of them, the Hyperledger Fabric, is used today to demonstrate the wide us
Autor:
Frances S. Li, Kathryn S. Carpentier, David W. Hawman, Cormac J. Lucas, Stephanie E. Ander, Heinz Feldmann, Thomas E. Morrison
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112418- (2023)
Summary: Arboviruses are public health threats that cause explosive outbreaks. Major determinants of arbovirus transmission, geographic spread, and pathogenesis are the magnitude and duration of viremia in vertebrate hosts. Previously, we determined
Externí odkaz:
https://doaj.org/article/2d0c7a1f21d4487fb3d8295abcdea33a
Autor:
Bennett J. Davenport, Alexis Catala, Stuart M. Weston, Robert M. Johnson, Jeremy Ardanuy, Holly L. Hammond, Carly Dillen, Matthew B. Frieman, Carlos E. Catalano, Thomas E. Morrison
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract The response by vaccine developers to the COVID-19 pandemic has been extraordinary with effective vaccines authorized for emergency use in the United States within 1 year of the appearance of the first COVID-19 cases. However, the emergence
Externí odkaz:
https://doaj.org/article/03afbb1c9970490d99c92fa16fc95fa3
Publikováno v:
Molecular and Cellular Biochemistry. 175:109-115
The phosphorylation of rat cardiac microsomal proteins was investigated with special attention to the effects of okadaic acid (an inhibitor of protein phosphatases), inhibitor 2 of protein phosphatase 1 and inhibitor of cyclic AMP-dependent protein k
Publikováno v:
Molecular and Cellular Biochemistry. 175:99-107
Myocytes were isolated from rat heart ventricles and then incubated with [32P]-sodium phosphate to label intracellular ATP stores. Incubations of the [32P]-labelled cardiomyocytes with a b-adrenoceptor agonist isoproterenol (10 µM) and with a plant