Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Thomas E. Gunter"'
Autor:
Abedalrazaq Alkukhun, Gregory Jon Anderson, Tayze T. Antunes, Michael Aschner, Terry J. Aspray, Thomas Bartnikas, Abdel A. Belaidi, Roberto Bravo-Sagua, Gregory A. Brent, George J. Brewer, Mona S. Calvo, Bradley Allen Carlson, Wen-Hsing Cheng, Sylvia Christakos, Mariana Cifuentes, James F. Collins, Puneet Dhawan, Ralph Marsland Duckworth, Lynnette Robyn Ferguson, David Michael Frazer, Toshiyuki Fukada, Kazuhisa Fukue, Priyanka V. Gangodkar, Eduardo Garcia-Fuentes, Michael D. Garrick, John P. Geibel, Fayez K. Ghishan, Vadim N. Gladyshev, A. Grubman, Thomas E. Gunter, Hajo Haase, Dolph Lee Hatfield, Ka He, Carolina Herrera, Kayo Ikuta, Francisco J. Rios, Sami Judeeba, Lillian J. Juttukonda, Taiho Kambe, Ichiro Kaneko, Yujian James Kang, Nishi Karunasinghe, Anuradha V. Khadilkar, Pawel R. Kiela, Katerine S. Knust, Mitchell D. Knutson, Yuko Komiya, Daniel Laubitz, Sergio Lavandero, Xin Gen Lei, Angela M. Leung, Anna Milanesi, Ken-ichi Miyamoto, Augusto C. Montezano, Stefano Mora, Armando Salim Munoz-Abraham, Forrest Harold Nielsen, Thirayost Nimmanon, Yukina Nishito, Tanara Vieira Peres, Anne-Laure Perraud, Michael Pettiglio, Nikhil D. Phadke, Ananda S. Prasad, Vijayababu M. Radhakrishnan, Marcela Reyes, Loren Warren Runnels, Carsten Schmitz, Guenter Schwarz, Hiroko Segawa, Yatrik Madhukar Shah, Eric P. Skaar, Laura Soldati, Michael Stowasser, Sawako Tatsumi, Kathryn M. Taylor, Ryuta Tobe, Rhian M. Touyz, Cari Lewis Tsinovoi, Petra Akiko Tsuji, Jaime Uribarri, Inés Velasco, Vaishali Veldurthy, Giuseppe Vezzoli, John Bertram Vincent, Tao Wang, Ran Wei, Marianne Wessling-Resnick, A.R. White, Ying Xiao, Xiang Xue, Hironori Yamamoto, Wen Yin, Wenjing Zhang, Fatemeh Vida Zohoori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4163b40ff28dadf005ba3c2eabf115
https://doi.org/10.1016/b978-0-12-802168-2.01002-2
https://doi.org/10.1016/b978-0-12-802168-2.01002-2
Autor:
Thomas E. Gunter
Although manganese is an essential biological element, large accumulations in the brain can lead to neurodegeneration characterized by cell death and loss of neurotransmitters, largely in the globus pallidus and striatum. Much of the initial damage i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287d2c22b169ceaf82fa03d2e3b94cec
https://doi.org/10.1016/b978-0-12-802168-2.00032-4
https://doi.org/10.1016/b978-0-12-802168-2.00032-4
Publikováno v:
Free Radical Biology and Medicine. 62:65-75
Manganese (Mn) is an essential dietary nutrient, but an excess or accumulation can be toxic. Disease states, such as manganism, are associated with overexposure or accumulation of Mn and are due to the production of reactive oxygen species, free radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8316a11049a3e0b7a6ff0aadd2f2ee92
https://doi.org/10.1016/j.freeradbiomed.2013.01.032
https://doi.org/10.1016/j.freeradbiomed.2013.01.032
Autor:
William M. Valentine, David I. Yule, Michael Aschner, Brent Gerstner, Robert Gelein, Jon Malecki, Thomas E. Gunter, Karlene K. Gunter
Publikováno v:
NeuroToxicology. 34:118-127
Excessive manganese (Mn) uptake by brain cells, particularly in regions like the basal ganglia, can lead to toxicity. Mn(2+) is transported into cells via a number of mechanisms, while Mn(3+) is believed to be transported similarly to iron (Fe) via t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d878204836b94556e2b10c04d3a5f8f
https://doi.org/10.1016/j.neuro.2012.10.018
https://doi.org/10.1016/j.neuro.2012.10.018
Autor:
Karen L. de Mesy Bentley, Jonathan M Malecki, Günter Oberdörster, Thomas E. Gunter, Alison Elder, Karlene K. Gunter, Beth VanWinkle, Irene M. Evans, Jacob N. Finkelstein
Publikováno v:
Nanotoxicology. 3:307-318
Mammalian cells take up nanoparticles (NPs) and some NPs increase ROS. We use imaging and measure ROS in parallel to evaluate NP-cell interactions with type I-like alveolar epithelial cells exposed to NPs at 1.2 µg/cm(2) . Titanium dioxide (Ti0(2)),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3820a3060e16ea08984be96bc738c8f7
https://doi.org/10.3109/17435390903121949
https://doi.org/10.3109/17435390903121949
Publikováno v:
NeuroToxicology. 27:765-776
Recent studies of speciation of manganese (Mn) in brain mitochondria, neuron-like cells, and astrocytes are reviewed. No evidence is found for oxidation of Mn(2+) complexes to a Mn(3+) complex. The only evidence for any Mn(3+) complex is found in a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122262e019e70dad33aefe098bd387b0
https://doi.org/10.1016/j.neuro.2006.05.002
https://doi.org/10.1016/j.neuro.2006.05.002
Autor:
Thomas E. Gunter
Publikováno v:
Manganese in Health and Disease ISBN: 9781849739436
The transition metal, manganese (Mn), has a complex chemistry and multiple oxidation states. Only three of these oxidation states, Mn2+, Mn3+, and Mn4+, have been found in living cells. Although Mn2+ is relatively stable and Mn4+ largely restricted t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b75753d6c179add6ccdf3d4285fc70ed
https://doi.org/10.1039/9781782622383-00158
https://doi.org/10.1039/9781782622383-00158
Autor:
Michael Aschner, Jason D. Salter, Thomas E. Gunter, Katie Anderson, Karlene K. Gunter, Sean T. Hammond, Roman A. Eliseev, Lisa M. Miller
Publikováno v:
Free Radical Biology and Medicine. 39:164-181
Excessive brain Mn can produce toxicity with symptoms resembling parkinsonism. This syndrome, called “manganism,” correlates with loss of dopamine in the striatum and cell death in the striatum and globus pallidus. A common hypothesis is that cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db347df715d1988127534f7bca8fc88
https://doi.org/10.1016/j.freeradbiomed.2005.03.004
https://doi.org/10.1016/j.freeradbiomed.2005.03.004
Publikováno v:
Journal of Biological Chemistry. 279:46748-46754
Treatment of various types of cells with the mitochondrial ATP-sensitive K+ channel opener, diazoxide, preconditions cells to subsequent injuries and inhibits apoptosis. The mechanism of such preconditioning is not well understood. We have studied th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd3149b47f7007d049d1d54a88bc4c9
https://doi.org/10.1074/jbc.m406217200
https://doi.org/10.1074/jbc.m406217200
Autor:
Andrei Alexandrov, Jason D. Salter, Thomas E. Gunter, Karlene K. Gunter, Roman A. Eliseev, Lisa M. Miller, Sean T. Hammond, Linas Buntinas, Claire E. Gavin
Publikováno v:
Journal of Neurochemistry. 88:266-280
Excess brain manganese can produce toxicity with symptoms that resemble those of Parkinsonism and causes that remain elusive. Manganese accumulates in mitochondria, a major source of superoxide, which can oxidize Mn2+ to the powerful oxidizing agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b38a12e70d646a0aace9cb5d53d8111
https://doi.org/10.1046/j.1471-4159.2003.02122.x
https://doi.org/10.1046/j.1471-4159.2003.02122.x