Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Thomas E. Darga"'
Autor:
Yves A. Lussier, Nikolai N. Khodarev, Kelly Regan, Kimberly Corbin, Haiquan Li, Sabha Ganai, Sajid A. Khan, Jennifer L. Gnerlich, Thomas E. Darga, Hanli Fan, Oleksiy Karpenko, Philip B. Paty, Mitchell C. Posner, Steven J. Chmura, Samuel Hellman, Mark K. Ferguson, Ralph R. Weichselbaum
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/3b9f89ecdc1c4cc29417ff167be9a09d
Autor:
Ralph R. Weichselbaum, Stephen J. Kron, Harold G. Sutton, Clayton Crawley, Juan Camilo Barreto-Andrade, Chaitali Chakraborty, Thomas E. Darga, Vytautas P. Bindokas, Edwardine Labay, Daniel W. Golden, Helena J. Mauceri, Elena V. Efimova
Persistent DNA double-strand breaks (DSB) may determine the antitumor effects of ionizing radiation (IR) by inducing apoptosis, necrosis, mitotic catastrophe, or permanent growth arrest. IR induces rapid modification of megabase chromatin domains sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51dd366adfcd6fd197205c71eafbd249
https://doi.org/10.1158/0008-5472.c.6500439
https://doi.org/10.1158/0008-5472.c.6500439
Autor:
Nikolai N. Khodarev, Ralph R. Weichselbaum, James J. Mezhir, Kerrington D. Smith, John Hart, Theodore Karrison, Masha Kocherginsky, Thomas E. Darga, James O. Park, Mitchell C. Posner, Erik T. Kimchi
Supplementary Table 2S from Progression of Barrett's Metaplasia to Adenocarcinoma Is Associated with the Suppression of the Transcriptional Programs of Epidermal Differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a767fb0842f079a3d3c724a0d16793c
https://doi.org/10.1158/0008-5472.22365102
https://doi.org/10.1158/0008-5472.22365102
Autor:
Ralph R. Weichselbaum, Stephen J. Kron, Harold G. Sutton, Clayton Crawley, Juan Camilo Barreto-Andrade, Chaitali Chakraborty, Thomas E. Darga, Vytautas P. Bindokas, Edwardine Labay, Daniel W. Golden, Helena J. Mauceri, Elena V. Efimova
Supplementary Methods, Figure Legends 1-6 from Poly(ADP-Ribose) Polymerase Inhibitor Induces Accelerated Senescence in Irradiated Breast Cancer Cells and Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46079600e00184645a6c0b173df8727e
https://doi.org/10.1158/0008-5472.22383135
https://doi.org/10.1158/0008-5472.22383135
Autor:
Nikolai N. Khodarev, Ralph R. Weichselbaum, James J. Mezhir, Kerrington D. Smith, John Hart, Theodore Karrison, Masha Kocherginsky, Thomas E. Darga, James O. Park, Mitchell C. Posner, Erik T. Kimchi
We did expressional profiling on 24 paired samples of normal esophageal epithelium, Barrett's metaplasia, and esophageal adenocarcinomas. Matching tissue samples representing the three different histologic types were obtained from each patient underg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3c9e0a15f19bbc11ae5214c123f37e
https://doi.org/10.1158/0008-5472.c.6494532.v1
https://doi.org/10.1158/0008-5472.c.6494532.v1
Autor:
Ralph R. Weichselbaum, Stephen J. Kron, Harold G. Sutton, Clayton Crawley, Juan Camilo Barreto-Andrade, Chaitali Chakraborty, Thomas E. Darga, Vytautas P. Bindokas, Edwardine Labay, Daniel W. Golden, Helena J. Mauceri, Elena V. Efimova
Supplementary Figures 1-6 from Poly(ADP-Ribose) Polymerase Inhibitor Induces Accelerated Senescence in Irradiated Breast Cancer Cells and Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb88416256c4ee7d9f8b58ee8ca8edc
https://doi.org/10.1158/0008-5472.22383138
https://doi.org/10.1158/0008-5472.22383138
Autor:
Yves A Lussier, Nikolai N Khodarev, Kelly Regan, Kimberly Corbin, Haiquan Li, Sabha Ganai, Sajid A Khan, Jennifer L Gnerlich, Thomas E Darga, Hanli Fan, Oleksiy Karpenko, Philip B Paty, Mitchell C Posner, Steven J Chmura, Samuel Hellman, Mark K Ferguson, Ralph R Weichselbaum
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50141 (2012)
Strategies to stage and treat cancer rely on a presumption of either localized or widespread metastatic disease. An intermediate state of metastasis termed oligometastasis(es) characterized by limited progression has been proposed. Oligometastases ar
Externí odkaz:
https://doaj.org/article/73006a35635b4085a0b0a3d2108fce6f
Autor:
Yves A Lussier, H Rosie Xing, Joseph K Salama, Nikolai N Khodarev, Yong Huang, Qingbei Zhang, Sajid A Khan, Xinan Yang, Michael D Hasselle, Thomas E Darga, Renuka Malik, Hanli Fan, Samantha Perakis, Matthew Filippo, Kimberly Corbin, Younghee Lee, Mitchell C Posner, Steven J Chmura, Samuel Hellman, Ralph R Weichselbaum
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28650 (2011)
Cancer staging and treatment presumes a division into localized or metastatic disease. We proposed an intermediate state defined by ≤ 5 cumulative metastasis(es), termed oligometastases. In contrast to widespread polymetastases, oligometastatic pat
Externí odkaz:
https://doaj.org/article/766dba8196f24b97a22c9a586ea38332
Autor:
Nikolai N Khodarev, Paul Roach, Sean P Pitroda, Daniel W Golden, Mihir Bhayani, Michael Y Shao, Thomas E Darga, Mara G Beveridge, Ravi F Sood, Harold G Sutton, Michael A Beckett, Helena J Mauceri, Mitchell C Posner, Ralph R Weichselbaum
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5821 (2009)
Traditionally IFN/STAT1 signaling is connected with an anti-viral response and pro-apoptotic tumor-suppressor functions. Emerging functions of a constitutively activated IFN/STAT1 pathway suggest an association with an aggressive tumor phenotype. We
Externí odkaz:
https://doaj.org/article/140c66eb354942779b0d25f8b67804dc
Autor:
Mark K. Ferguson, Lei Huang, Mitchell C. Posner, Thomas E. Darga, Go Oshima, Sean C. Wightman, Huiping Liu, Samuel Hellman, Abhineet Uppal, Stephen Mallon, Sean P. Pitroda, Ralph R. Weichselbaum, Qingbei Zhang, Geoffrey L. Greene, Xiaona Huang, Jorge Andrade, Nikolai N. Khodarev
Publikováno v:
Oncotarget
Oligometastasis is a clinically distinct subset of metastasis characterized by a limited number of metastases potentially curable with localized therapies. We analyzed pathways targeted by microRNAs over-expressed in clinical oligometastasis samples