Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Thomas E Maher"'
Autor:
Federica Raguseo, Yiran Wang, Jessica Li, Marija Petrić Howe, Rubika Balendra, Anouk Huyghebaert, Devkee M. Vadukul, Diana A. Tanase, Thomas E. Maher, Layla Malouf, Roger Rubio-Sánchez, Francesco A. Aprile, Yuval Elani, Rickie Patani, Lorenzo Di Michele, Marco Di Antonio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases that exist on a clinico-pathogenetic spectrum, designated ALS/FTD. The most common genetic cause of ALS/FTD is expansion of the intronic hex
Externí odkaz:
https://doaj.org/article/7acb7c2915fa45d693187ddf1818d97f
Autor:
Federica Raguseo, Diana A. Tanase, Thomas E. Maher, Layla Malouf, Roger Rubio-Sánchez, Yuval Elani, Lorenzo Di Michele, Marco Di Antonio
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two neurodegenerative diseases genetically characterised by the expansion of the hexanucleotide repeat (GGGGCC)n. Here we investigated the formation of nucleic-acid secondary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9a38bc01acff85e1fbfec341671ffde
https://doi.org/10.1101/2023.01.31.526399
https://doi.org/10.1101/2023.01.31.526399
Publikováno v:
Angewandte Chemie. 134
Publikováno v:
Angewandte Chemie (International ed. in English). 61(24)
Unprecedented bacterial targets are urgently needed to overcome the resistance crisis. Herein we systematically mine pyridoxal phosphate-dependent enzymes (PLP-DEs) in bacteria to focus on a target class which is involved in crucial metabolic process
Autor:
Stephan M. Hacker, Alexey I. Nesvizhskii, F. Dean Toste, Kathrin Lang, Christopher Chang, Marko Cigler, Thomas E. Maher, Patrick Raunft, Dario Mrdović, Kristina Krauskopf, Michael Zollo, Lisa Lewald, Patricia Musacchio, Fengchao Yu, Patrick R. A. Zanon
Targeted covalent inhibitors are powerful entities in drug discovery, but their application has so far mainly been limited to addressing cysteine residues. The development of cysteine-directed covalent inhibitors has largely profited from determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8b8ff3eb2ec76a034ba8cfd0c96a1e
https://doi.org/10.26434/chemrxiv-2021-w7rss-v2
https://doi.org/10.26434/chemrxiv-2021-w7rss-v2
Publikováno v:
Management Research News. 26:1-11
The transfer of technology from the foreign partner to the domestic partner has been a problem for international joint ventures throughout the world, but particularly in China. Because of the nature of organisational learning, especially in its tacit
The hesitant transfer of strategic management know‐how to foreign wholly owned subsidiaries in China
Publikováno v:
Management Research News. 25:42-56
The seconf of two articles on the transfer from foreign companies to affiliates in China. Addresses wholly owned subsidiaries. Tries to determine strategic management know‐how and if it is currently being transferred. Attempts to forecast the likel
Publikováno v:
Management Research News. 25:1-15
Briefly outlines the development and attraction of the “joint venture” approach to foreign investment in China. Provides a number of in‐depth interviews with top management personnel of five well‐known international joint ventures. Attempts t
Publikováno v:
Management Research News. 24:17-24
States that competitive advantage is like a moving target, changing over time as market conditions, consumer demand and resource availability vary. Provides a case study of Taiwan’s present advantages within the heights of the Asian economic growth
Publikováno v:
Asia Pacific Journal of Marketing and Logistics. 12:3-21
Looks at the problems of logistics in military operations and today’s commercial businesses. Traces the development of logistics management from a subordinate activity within a product producing entity to its performance by a separate entity which