Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Thomas E Dick"'
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
Rett syndrome, a severe X-linked neurodevelopmental disorder caused by mutations in the gene encoding methyl-CpG-binding protein 2 (Mecp2), is associated with a highly irregular respiratory pattern including severe upper-airway dysfunction. Recent wo
Externí odkaz:
https://doaj.org/article/b435c956f99142b99a7d95fdad81e3ba
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
The medullary respiratory network generates respiratory rhythm via sequential phase switching, which in turn is controlled by multiple feedbacks including those from the pons and nucleus tractus solitarii; the latter mediates pulmonary afferent feedb
Externí odkaz:
https://doaj.org/article/51c345245c284befb4e51f2dde397838
Publikováno v:
Frontiers in Computational Neuroscience, Vol 4 (2010)
We have combined neurophysiologic recording, statistical analysis, and computational modeling to investigate the dynamics of the respiratory network in the brainstem. Using a multielectrode array, we recorded ensembles of respiratory neurons in perfu
Externí odkaz:
https://doaj.org/article/2d88fdc533ba4b9e909503219c37d037
Autor:
Philippa M. Warren, Stephanie C. Steiger, Thomas E. Dick, Peter M. MacFarlane, Warren J. Alilain, Jerry Silver
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Respiratory failure is one of the leading causes of death following spinal cord injury and it is unclear if normal respiratory motor activity can be recovered after chronic injury-induced paralysis. Here, authors show that treatment with chondroitina
Externí odkaz:
https://doaj.org/article/855272d6d1de435e917538c553e07920
Autor:
Kofi-Kermit A. Horton, Cara K. Campanaro, Caitlyn Clifford, David E. Nethery, Kingman P. Strohl, Frank J. Jacono, Thomas E. Dick
Publikováno v:
Cannabis and Cannabinoid Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f050eeaed3352e410c1ac599c3b76228
https://doi.org/10.1089/can.2021.0085
https://doi.org/10.1089/can.2021.0085
Autor:
Elizaveta M. Latash, Robert A. Capps, William H. Barnett, Erica A. Wehrwein, Yaroslav I. Molkov, Thomas E. Dick
Publikováno v:
J Appl Physiol (1985)
Excessive blood pressure variation is linked to the development of hypertension and other diseases. This study assesses the relative role of respiratory sinus arrhythmia (RSA) and pulse pressure (PP) on the amplitude and timing of blood pressure vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea79c57202812718d2b5b15f96f2bd0
https://doi.org/10.1152/japplphysiol.00452.2020
https://doi.org/10.1152/japplphysiol.00452.2020
Autor:
Corey Smith, Thomas E. Dick, David Litvin, Lauren F. Borkowski, Frank J. Jacono, Scott J. Denstaedt, Nicole L. Nichols
Publikováno v:
Brain Behav Immun
The pathways for peripheral-to-central immune communication (P → C I-comm) following sterile lung injury (SLI) are unknown. SLI evokes systemic and central inflammation, which alters central respiratory control and viscerosensory transmission in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7883cbb9b5218453a1fa221ebcab0789
https://doi.org/10.1016/j.bbi.2020.02.006
https://doi.org/10.1016/j.bbi.2020.02.006
Autor:
David Nethery, Yee-Hsee Hsieh, Abigail Rose Zaylor, Frank J. Jacono, Thomas E. Dick, David Litvin
Publikováno v:
The Journal of Physiology. 598:2791-2811
Key points Compared with sham rats, rats a week after acute lung injury (ALI) express more pro-inflammatory cytokines in their brainstem respiratory control nuclei, exhibit a higher respiratory frequency (fR) and breathe with a more predictable patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73aa2486ea11c1f3dc208b7631246dd9
https://doi.org/10.1113/jp279177
https://doi.org/10.1113/jp279177
Publikováno v:
The Journal of Physiology. 598:2061-2079
Key points The functional neuroanatomy of the mammalian respiratory network is far from being understood since experimental tools that measure neural activity across this brainstem-wide circuit are lacking. Here, we use silicon multi-electrode arrays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d1457a078c83fac6655868eca170fa
https://doi.org/10.1113/jp279605
https://doi.org/10.1113/jp279605
Publikováno v:
Respir Physiol Neurobiol
We hypothesize that ventilatory pattern variability (VPV) varies with the magnitude of acute lung injury (ALI). In adult male rats, we instilled a low- or high- dose of bleomycin or saline (PBS) intratracheally. While representative samples of pulmon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc49ba5f25ce592db7d0c6cfed71cdb8
https://doi.org/10.1016/j.resp.2019.03.009
https://doi.org/10.1016/j.resp.2019.03.009