Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Thomas E, Morrison"'
Autor:
Thu A. Doan, Tadg S. Forward, Johnathon B. Schafer, Erin D. Lucas, Ira Fleming, Aspen Uecker-Martin, Edgardo Ayala, Jenna J. Guthmiller, Jay R. Hesselberth, Thomas E. Morrison, Beth A. Jirón Tamburini
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Antigens from viruses or immunizations can persist or are archived in lymph node stromal cells such as lymphatic endothelial cells (LEC) and fibroblastic reticular cells (FRC). Here, we find that, during the time frame of antigen archiving,
Externí odkaz:
https://doaj.org/article/c51ada010dc34878b794df452efbd18b
Autor:
Peiqi Yin, Nicholas A. May, Laura Sandra Lello, Atef Fayed, M. Guston Parks, Adam M. Drobish, Sainan Wang, Meghan Andrews, Zachary Sticher, Alexander A. Kolykhalov, Michael G. Natchus, George R. Painter, Andres Merits, Margaret Kielian, Thomas E. Morrison
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Chikungunya virus (CHIKV) is an enveloped, positive-sense RNA virus that has re-emerged to cause millions of human infections worldwide. In humans, acute CHIKV infection causes fever and severe muscle and joint pain. Chronic and debilitating
Externí odkaz:
https://doaj.org/article/dfff5e12899b43dd9c8db8e7247e88db
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1011794 (2024)
Infection by chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes severe polyarthralgia and polymyalgia, which can last in some people for months to years. Chronic CHIKV disease signs and symptoms are associated with the persistence of vira
Externí odkaz:
https://doaj.org/article/dc18606325354d899c3e8a7944242b74
Autor:
Autumn C. Holmes, Cormac J. Lucas, Morgan E. Brisse, Brian C. Ware, Heather D. Hickman, Thomas E. Morrison, Michael S. Diamond
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113876- (2024)
Summary: Alphaviruses are mosquito-transmitted pathogens that induce high levels of viremia, which facilitates dissemination and vector transmission. One prevailing paradigm is that, after skin inoculation, alphavirus-infected resident dendritic cell
Externí odkaz:
https://doaj.org/article/dd85bfbcd96b40e78b5375c2d78a42f8
Autor:
Stephanie E. Ander, Kathryn S. Carpentier, Wes Sanders, Cormac J. Lucas, Austin J. Jolly, Cydney N. Johnson, David W. Hawman, Mark T. Heise, Nathaniel J. Moorman, Thomas E. Morrison
Publikováno v:
Viruses, Vol 16, Iss 6, p 861 (2024)
We previously reported that deletion of a 44-nucleotide element in the 3′ untranslated region (UTR) of the Chikungunya virus (CHIKV) genome enhances the virulence of CHIKV infection in mice. Here, we find that while this 44-nucleotide deletion enha
Externí odkaz:
https://doaj.org/article/de9d1c236b594b4e9eb72f3e4301308c
Autor:
Frances S. Li, Kathryn S. Carpentier, David W. Hawman, Cormac J. Lucas, Stephanie E. Ander, Heinz Feldmann, Thomas E. Morrison
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112418- (2023)
Summary: Arboviruses are public health threats that cause explosive outbreaks. Major determinants of arbovirus transmission, geographic spread, and pathogenesis are the magnitude and duration of viremia in vertebrate hosts. Previously, we determined
Externí odkaz:
https://doaj.org/article/2d0c7a1f21d4487fb3d8295abcdea33a
Autor:
Bennett J. Davenport, Alexis Catala, Stuart M. Weston, Robert M. Johnson, Jeremy Ardanuy, Holly L. Hammond, Carly Dillen, Matthew B. Frieman, Carlos E. Catalano, Thomas E. Morrison
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract The response by vaccine developers to the COVID-19 pandemic has been extraordinary with effective vaccines authorized for emergency use in the United States within 1 year of the appearance of the first COVID-19 cases. However, the emergence
Externí odkaz:
https://doaj.org/article/03afbb1c9970490d99c92fa16fc95fa3
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010474 (2022)
Many viruses utilize the lymphohematogenous route for dissemination; however, they may not freely use this highway unchecked. The reticuloendothelial system (RES) is an innate defense system that surveys circulating blood, recognizing and capturing v
Externí odkaz:
https://doaj.org/article/fa0ea8138bad4fa6a7b9bc4af493aeec
Autor:
William Jonathan Windsor, Yannik Roell, Heidi Tucker, Chi-An Cheng, Sara Suliman, Laura J. Peek, Gary A. Pestano, William T. Lee, Heinz Zeichhardt, Molly M. Lamb, Martin Kammel, Hui Wang, Ross Kedl, Cody Rester, Thomas E. Morrison, Bennet J. Davenport, Kyle Carson, Jennifer Yates, Kelly Howard, Karen Kulas, David R. Walt, Aner Dafni, Daniel Taylor, May Chu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
BackgroundThere is an urgent need for harmonization between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serology platforms and assays prior to defining appropriate correlates of protection and as well inform the development of new ra
Externí odkaz:
https://doaj.org/article/3ec7571617af45718e06f6040746fb43
Autor:
Kurt R. Stenmark, Maria G. Frid, Evgenia Gerasimovskaya, Hui Zhang, Mary K. McCarthy, Joshua M. Thurman, Thomas E. Morrison
Publikováno v:
Pulmonary Circulation, Vol 11 (2021)
The outbreak of COVID-19 disease, caused by SARS-CoV-2 beta-coronovirus, urges a focused search for the underlying mechanisms and treatment options. The lung is the major target organ of COVID-19, wherein the primary cause of mortality is hypoxic res
Externí odkaz:
https://doaj.org/article/63f5c264a34541c0b3eee62916a43bdb