Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Thomas E, Gorochowski"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Careful consideration of how we approach design is crucial to all areas of biotechnology. However, choosing or developing an effective design methodology is not always easy as biology, unlike most areas of engineering, is able to adapt and e
Externí odkaz:
https://doaj.org/article/4c4c33e768924a09affa565adda22459
Autor:
Martyn Dade-Robertson, Pierangelo Gobbo, Thomas E. Gorochowski, Peter Quoc Nguyen, Meng Zhang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/96a657f2769a48429f082b38ef2ccb0d
Publikováno v:
BioDesign Research, Vol 6 (2024)
Living cells are exquisitely tuned to sense and respond to changes in their environment. Repurposing these systems to create engineered biosensors has seen growing interest in the field of synthetic biology and provides a foundation for many innovati
Externí odkaz:
https://doaj.org/article/2626c46e1f0d49e5bc1064198c670594
Autor:
Casey-Tyler Berezin, Luis U Aguilera, Sonja Billerbeck, Philip E Bourne, Douglas Densmore, Paul Freemont, Thomas E Gorochowski, Sarah I Hernandez, Nathan J Hillson, Connor R King, Michael Köpke, Shuyi Ma, Katie M Miller, Tae Seok Moon, Jason H Moore, Brian Munsky, Chris J Myers, Dequina A Nicholas, Samuel J Peccoud, Wen Zhou, Jean Peccoud
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011652 (2023)
Information is the cornerstone of research, from experimental (meta)data and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging laboratory information management syste
Externí odkaz:
https://doaj.org/article/b4c56a843deb47c5a60ffccf01b872d9
Publikováno v:
Royal Society Open Science, Vol 10, Iss 11 (2023)
The vast microbial biodiversity of soils is beginning to be observed and understood by applying modern DNA sequencing techniques. However, ensuring this potentially valuable information is used in a fair and equitable way remains a challenge. Here, w
Externí odkaz:
https://doaj.org/article/4262f9e5086546089252924ebb8ec21e
Autor:
Ioana M Gherman, Zahraa S Abdallah, Wei Pang, Thomas E Gorochowski, Claire S Grierson, Lucia Marucci
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 4, p e1010988 (2023)
Mechanistic models have been used for centuries to describe complex interconnected processes, including biological ones. As the scope of these models has widened, so have their computational demands. This complexity can limit their suitability when r
Externí odkaz:
https://doaj.org/article/c4c8a58fa00c4437b06968a41f641a69
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Transcriptional terminators are generally viewed as hard endpoints for transcribing RNA polymerases. Here, the authors reimagine terminators as transcriptional valves with predictable read through. They engineer and characterize 1780 valves and use t
Externí odkaz:
https://doaj.org/article/48474565a21a425780934f569031621f
Autor:
Dandan Zhang, Thomas E. Gorochowski, Lucia Marucci, Hyun-Taek Lee, Bruno Gil, Bing Li, Sabine Hauert, Eric Yeatman
Publikováno v:
Frontiers in Robotics and AI, Vol 9 (2023)
Recent technological advances in micro-robotics have demonstrated their immense potential for biomedical applications. Emerging micro-robots have versatile sensing systems, flexible locomotion and dexterous manipulation capabilities that can signific
Externí odkaz:
https://doaj.org/article/5eed69d8f15e4556a4065f77ae5dcb48
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Effective biological engineering requires the acknowledgement of evolution and its consideration during the design process. In this perspective, the authors present the concept of the evotype to reason about and shape the evolutionary potential of na
Externí odkaz:
https://doaj.org/article/8d8a5be3fdd2470dba4874351a4059ea
Publikováno v:
Advanced Intelligent Systems, Vol 4, Iss 7, Pp n/a-n/a (2022)
Engineering microscopic collectives of cells or microrobots is challenging due to the often limited capabilities of the individual agents, the inability to reliably program their motion and local interactions, and difficulties visualizing their behav
Externí odkaz:
https://doaj.org/article/e735b7878f5449a3a51e0de5b1122df8