Predicting the subcellular localization of viral proteins within a mammalian host cell

Autor: Thomas DY, Oomen R, Scott MS, Hallett MT

Publikováno v: Virology Journal, Vol 3, Iss 1, p 24 (2006)

Abstract Background The bioinformatic prediction of protein subcellular localization has been extensively studied for prokaryotic and eukaryotic organisms. However, this is not the case for viruses whose proteins are often involved in extensive inter

Externí odkaz: https://doaj.org/article/308a27437129456ea9ce4edc84c2a28f

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

Autor: Maurel, M, Obacz, J, Avril, T, Ding, Y-P, Papadodima, O, Treton, X, Daniel, F, Pilalis, E, Hörberg, J, Hou, W, Beauchamp, M-C, Tourneur-Marsille, J, Cazals-Hatem, D, Sommerova, L, Samali, A, Tavernier, J, Hrstka, R, Dupont, A, Fessart, D, Delom, F, Fernandez-Zapico, ME, Jansen, G, Eriksson, LA, Thomas, DY, Jerome-Majewska, L, Hupp, T, Chatziioannou, A, Chevet, E, Ogier-Denis, E

Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2019, 11 (6), pp.e10120. ⟨10.15252/emmm.201810120⟩
EMBO Molecular Medicine, 2019, 11 (6), pp.e10120. ⟨10.15252/emmm.201810120⟩
Maurel, M, Obacz, J, Avril, T, Ding, YP, Papadodima, O, Treton, X, Daniel, F, Pilalis, E, Hörberg, J, Hou, W, Beauchamp, MC, Tourneur-Marsille, J, Cazals-Hatem, D, Sommerova, L, Samali, A, Tavernier, J, Hrstka, R, Dupont, A, Fessart, D, Delom, F, Fernandez-Zapico, M E, Jansen, G, Eriksson, L A, Thomas, D Y, Jerome-Majewska, L, Hupp, T, Chatziioannou, A, Chevet, E & Ogier-Denis, E 2019, ' Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation ', EMBO Molecular Medicine, vol. 11, no. 6, e10120 . https://doi.org/10.15252/emmm.201810120
EMBO Molecular Medicine, Vol 11, Iss 6, Pp n/a-n/a (2019)

International audience; Anterior gradient 2 (AGR2) is a dimeric protein disulfide isomerase family member involved in the regulation of protein quality control in the endoplasmic reticulum (ER). Mouse AGR2 deletion increases intestinal inflammation a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b158ee751accfe7bf8b7a48bbd1fbcb
https://pubmed.ncbi.nlm.nih.gov/31040128

TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases via cAMP/Gαs signaling

Autor: Masyuk, Tatyana V, Masyuk, Anatoliy I, Pisarello, Maria Lorenzo, Howard, Brynn N, Huang, Bing Q, Lee, Pui-Yuen, Fung, Xavier, Sergienko, Eduard, Ardesky, Robert J, Chung, Thomas DY, Pinkerton, Anthony B, LaRusso, Nicholas F

Hepatic cystogenesis in Polycystic Liver Disease (PLD) is associated with increased levels of cAMP in cholangiocytes lining liver cysts. TGR5, a G protein-coupled bile acid receptor, is linked to cAMP and expressed in cholangiocytes. Therefore, we hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d372ff88b3aaa6e1f0f815f24bee73b6
https://europepmc.org/articles/PMC5605412/

Motivating and Engaging Students: Reflections on Gamifying Online Courses Through a Digital Badging Program

Autor: Thomas Dyer, R. Jacob Aroz

Publikováno v: Journal of Scholarly Engagement, Vol 5, Iss 2, Pp 44-55 (2022)

The purpose of this reflective critique was to explore faculty approaches to engage and motivate students while promoting community and building skills in the online classroom. One of the primary benefits of this critique is to bring focus to this of

Externí odkaz: https://doaj.org/article/b358ae06adb248e3a420c4ad06cb908f

Hip arthroscopy after periacetabular osteotomy for acetabular dysplasia – incidence and clinical outcome

Autor: Pierre Laboudie, Thomas Dymond, Cheryl Kreviazuk, George Grammatopoulos, Paul E. Beaulé

Publikováno v: BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-8 (2022)

Abstract Background The periacetabular osteotomy (PAO) is the treatment of choice for acetabular dysplasia and has demonstrated improvement in patient reported outcomes measures (PROMs) as well as acceptable long-term survival. However, acetabular dy

Externí odkaz: https://doaj.org/article/1d3f5b4ddb6e4562a1395ff7c5a41e33