Tankyrase-1 regulates RBP-mediated mRNA turnover to promote muscle fiber formation.

Autor: Mubaid S; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Sanchez BJ; KAUST Smart-Health Initiative (KSHI) and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Jeddah, Saudi Arabia., Algehani RA; KAUST Smart-Health Initiative (KSHI) and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Jeddah, Saudi Arabia., Skopenkova V; KAUST Smart-Health Initiative (KSHI) and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Jeddah, Saudi Arabia., Adjibade P; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Hall DT; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Busque S; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Lian XJ; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Ashour K; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Tremblay AK; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Carlile G; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada., Gagné JP; Centre de recherche du CHU de Québec-Pavillon CHUL, Faculté de Médecine, Université Laval, Québec G1V 4G2, Canada., Diaz-Gaxiola A; KAUST Smart-Health Initiative (KSHI) and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Jeddah, Saudi Arabia., Khattak S; KAUST Smart-Health Initiative (KSHI) and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Jeddah, Saudi Arabia., Di Marco S; KAUST Smart-Health Initiative (KSHI) and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Jeddah, Saudi Arabia.; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada., Thomas DY; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada., Poirier GG; Centre de recherche du CHU de Québec-Pavillon CHUL, Faculté de Médecine, Université Laval, Québec G1V 4G2, Canada., Gallouzi IE; KAUST Smart-Health Initiative (KSHI) and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Jeddah, Saudi Arabia.; Dept. of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, QC H3G 1Y6, Canada.; Rosalind & Morris Goodman Cancer Institute, McGill University, 1160 Pine Avenue, Montreal, QC H3A 1A3, Canada.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Apr 24; Vol. 52 (7), pp. 4002-4020.

Ionocyte-Specific Regulation of Cystic Fibrosis Transmembrane Conductance Regulator.

Autor: Sato Y; Department of Physiology.; Cystic Fibrosis Translational Research Center., Kim D; Department of Physiology.; Cystic Fibrosis Translational Research Center., Turner MJ; Department of Physiology.; Cystic Fibrosis Translational Research Center., Luo Y; Department of Physiology.; Cystic Fibrosis Translational Research Center., Zaidi SSZ; Department of Physiology.; Cystic Fibrosis Translational Research Center., Thomas DY; Cystic Fibrosis Translational Research Center.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada, and., Hanrahan JW; Department of Physiology.; Cystic Fibrosis Translational Research Center.; Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2023 Sep; Vol. 69 (3), pp. 281-294.

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

Autor: Maurel, M, Obacz, J, Avril, T, Ding, Y-P, Papadodima, O, Treton, X, Daniel, F, Pilalis, E, Hörberg, J, Hou, W, Beauchamp, M-C, Tourneur-Marsille, J, Cazals-Hatem, D, Sommerova, L, Samali, A, Tavernier, J, Hrstka, R, Dupont, A, Fessart, D, Delom, F, Fernandez-Zapico, ME, Jansen, G, Eriksson, LA, Thomas, DY, Jerome-Majewska, L, Hupp, T, Chatziioannou, A, Chevet, E, Ogier-Denis, E

Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2019, 11 (6), pp.e10120. ⟨10.15252/emmm.201810120⟩
EMBO Molecular Medicine, 2019, 11 (6), pp.e10120. ⟨10.15252/emmm.201810120⟩
Maurel, M, Obacz, J, Avril, T, Ding, YP, Papadodima, O, Treton, X, Daniel, F, Pilalis, E, Hörberg, J, Hou, W, Beauchamp, MC, Tourneur-Marsille, J, Cazals-Hatem, D, Sommerova, L, Samali, A, Tavernier, J, Hrstka, R, Dupont, A, Fessart, D, Delom, F, Fernandez-Zapico, M E, Jansen, G, Eriksson, L A, Thomas, D Y, Jerome-Majewska, L, Hupp, T, Chatziioannou, A, Chevet, E & Ogier-Denis, E 2019, ' Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation ', EMBO Molecular Medicine, vol. 11, no. 6, e10120 . https://doi.org/10.15252/emmm.201810120
EMBO Molecular Medicine, Vol 11, Iss 6, Pp n/a-n/a (2019)

International audience; Anterior gradient 2 (AGR2) is a dimeric protein disulfide isomerase family member involved in the regulation of protein quality control in the endoplasmic reticulum (ER). Mouse AGR2 deletion increases intestinal inflammation a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b158ee751accfe7bf8b7a48bbd1fbcb
https://pubmed.ncbi.nlm.nih.gov/31040128

The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway.

Autor: Carlile GW; Department of Biochemistry, Cystic Fibrosis Translational Research Centre, McGill University, McIntyre Medical Sciences Building, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada. graeme.carlile@mcgill.ca.; Department of Human Genetics, Cystic Fibrosis Translational Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada. graeme.carlile@mcgill.ca., Yang Q; Department of Biochemistry, Cystic Fibrosis Translational Research Centre, McGill University, McIntyre Medical Sciences Building, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada.; Department of Human Genetics, Cystic Fibrosis Translational Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada., Matthes E; Department of Physiology, McGill Cystic Fibrosis Translational Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada., Liao J; Department of Physiology, McGill Cystic Fibrosis Translational Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada., Birault V; Translation Department, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK., Sneddon HF; Department of Chemistry, Green Chemistry Centre of Excellence, University of York, Heslington, York, YO10 5DD, UK., Poole DL; Medicinal Chemistry, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Hall CJ; Medicinal Chemistry, GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, UK., Hanrahan JW; Department of Physiology, McGill Cystic Fibrosis Translational Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada., Thomas DY; Department of Biochemistry, Cystic Fibrosis Translational Research Centre, McGill University, McIntyre Medical Sciences Building, 3655 Promenade Sir William Osler, Montreal, QC, H3G 1Y6, Canada.; Department of Human Genetics, Cystic Fibrosis Translational Research Centre, McGill University, Montreal, QC, H3G 1Y6, Canada.

Publikováno v: Scientific reports [Sci Rep] 2022 Mar 17; Vol. 12 (1), pp. 4595. Date of Electronic Publication: 2022 Mar 17.

Predicting the subcellular localization of viral proteins within a mammalian host cell

Autor: Thomas DY, Oomen R, Scott MS, Hallett MT

Publikováno v: Virology Journal, Vol 3, Iss 1, p 24 (2006)

Abstract Background The bioinformatic prediction of protein subcellular localization has been extensively studied for prokaryotic and eukaryotic organisms. However, this is not the case for viruses whose proteins are often involved in extensive inter

Externí odkaz: https://doaj.org/article/308a27437129456ea9ce4edc84c2a28f