Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Thomas Dupas"'
Autor:
Thomas Dupas, Amandine Vergnaud, Thomas Pelé, Angélique Blangy-Letheule, Virginie Aillerie, Martin Bouaud, Angélique Erraud, Anaïs Maillard, Dorian Hassoun, Antoine Persello, Jules Lecomte, Matthieu Rivière, Arnaud Tessier, Aurélia A. Leroux, Bertrand Rozec, Manon Denis, Benjamin Lauzier
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Anaesthetics are used daily in human and veterinary medicine as well as in scientific research. Anaesthetics have an impact on cell homeostasis especially through modulation of protein post-translational modifications. O-GlcNAcylation, a ubi
Externí odkaz:
https://doaj.org/article/e452d8210ce14234a433641666b18974
Autor:
Antoine Persello, Thomas Dupas, Amandine Vergnaud, Angélique Blangy-Letheule, Virginie Aillerie, Angélique Erraud, Yannick Guilloux, Manon Denis, Benjamin Lauzier
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30526- (2024)
Background: Dietary intake and metabolism variations are associated with molecular changes and more particularly in the transcriptome. O-GlcNAcylation is a post-translational modification added and removed respectively by OGT and OGA. The UDP-GlcNAc,
Externí odkaz:
https://doaj.org/article/a4b754beae4c40c19d7ddc9d66ef9bc8
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-15 (2023)
Abstract Histones display a wide variety of post-translational modifications, including acetylation, methylation, and phosphorylation. These epigenetic modifications can influence chromatin structure and function without altering the DNA sequence. Hi
Externí odkaz:
https://doaj.org/article/194256c4586949d6baaa1b9f1bd6ea60
Autor:
Antoine Persello, Fouzia Souab, Thomas Dupas, Virginie Aillerie, Edith Bigot, Manon Denis, Angélique Erraud, Thomas Pelé, Angélique Blangy-Letheule, Pierre Miniou, Philippe Guedat, Michel De Waard, Emmanuelle Abgueguen, Bertrand Rozec, Benjamin Lauzier
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7338 (2023)
In clinical practice, extracorporeal circulation (ECC) is associated with coagulopathy and inflammation, eventually leading to organ injuries without preventive systemic pharmacological treatment. Relevant models are needed to reproduce the pathophys
Externí odkaz:
https://doaj.org/article/9abcff36ac6d48cd9b3b6dbf00dd042a
Autor:
Angélique Blangy-Letheule, Amandine Vergnaud, Thomas Dupas, Bertrand Rozec, Benjamin Lauzier, Aurélia A. Leroux
Publikováno v:
Cells, Vol 12, Iss 7, p 1052 (2023)
Sepsis is a life-threatening disease defined as an organ dysfunction caused by a dysregulated host response to an infection. Early diagnosis and prognosis of sepsis are necessary for specific and timely treatment. However, no predictive biomarkers or
Externí odkaz:
https://doaj.org/article/4eaedae455204d62bcf49eb924cbe089
Autor:
Thomas Dupas, Antoine Persello, Angélique Blangy-Letheule, Manon Denis, Angélique Erraud, Virginie Aillerie, Aurélia A. Leroux, Matthieu Rivière, Jacques Lebreton, Arnaud Tessier, Bertrand Rozec, Benjamin Lauzier
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6430 (2022)
The young population, which is particularly at risk of sepsis, is, paradoxically, rarely studied. Acute stimulation of O-GlcNAcylation, a post-translational modification involved in metabolic regulation, cell survival and stress response, is benefici
Externí odkaz:
https://doaj.org/article/8c4eca45865f4f15bd0a83e3ad78e746
Autor:
Manon Denis, Thomas Dupas, Antoine Persello, Justine Dontaine, Laurent Bultot, Charlotte Betus, Thomas Pelé, Justine Dhot, Angélique Erraud, Anaïs Maillard, Jérôme Montnach, Aurélia A. Leroux, Edith Bigot-Corbel, Didier Vertommen, Matthieu Rivière, Jacques Lebreton, Arnaud Tessier, Michel De Waard, Luc Bertrand, Bertrand Rozec, Benjamin Lauzier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9236 (2021)
Sepsis in the young population, which is particularly at risk, is rarely studied. O-GlcNAcylation is a post-translational modification involved in cell survival, stress response and metabolic regulation. O-GlcNAc stimulation is beneficial in adult se
Externí odkaz:
https://doaj.org/article/e9d2fb6c73e4487a8654807b03076041
Autor:
Amandine Vergnaud, Thomas Dupas, Virginie Aillerie, Antoine Persello, Thomas Pele, Angélique Blangy-Letheule, Angelique Erraud, Aurore Girardeau, Barbara Ribeiro, Jérôme Montnach, Michel De Waard, Bertrand Rozec, Benjamin Lauzier
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 15:195
Autor:
Thomas Dupas, Charlotte Betus, Angélique Blangy-Letheule, Thomas Pelé, Antoine Persello, Manon Denis, Benjamin Lauzier
Publikováno v:
The international journal of biochemistrycell biology. 151
O-GlcNAcylation is a post-translational modification which affects approximately 5000 human proteins. Its involvement has been shown in many if not all biological processes. Variations in O-GlcNAcylation levels can be associated with the development
Autor:
Thomas Dupas, Thomas Pelé, Justine Dhot, Mélanie Burban, Antoine Persello, Virginie Aillerie, Angélique Erraud, Angela Tesse, David Stevant, Angélique Blangy-Letheule, Céline Menguy, Vincent Sauzeau, Michel De Waard, Bertrand Rozec, Chantal Gauthier, Benjamin Lauzier
Publikováno v:
Oxidative medicine and cellular longevity. 2022
50% of patients with heart failure have a preserved ejection fraction (HFpEF). Numerous studies have investigated the pathophysiological mechanisms of HFpEF and have shown that endothelial dysfunction plays an important role in HFpEF. Yet no studies