Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Thomas Dumortier"'
Qualifying a Novel Clinical Trial Endpoint (iBOX) Predictive of Long-Term Kidney Transplant Outcomes
Autor:
Amanda Klein, Alexandre Loupy, Mark Stegall, Ilkka Helanterä, Luke Kosinski, Eric Frey, Olivier Aubert, Gillian Divard, Kenneth Newell, Herwig-Ulf Meier-Kriesche, Roslyn Mannon, Thomas Dumortier, Varun Aggarwal, Jagdeep T. Podichetty, Inish O’Doherty, Ahmed Osama Gaber, William E. Fitzsimmons
Publikováno v:
Transplant International, Vol 36 (2023)
New immunosuppressive therapies that improve long-term graft survival are needed in kidney transplant. Critical Path Institute’s Transplant Therapeutics Consortium received a qualification opinion for the iBOX Scoring System as a novel secondary ef
Externí odkaz:
https://doaj.org/article/30625a9a0ea742bbb206416f92a9eb5a
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 6, Pp 589-598 (2021)
Abstract Pediatric extrapolation is essential for bringing treatments to the pediatric population, especially for indications where the recruitment of pediatric patients into clinical trials is difficult and where fully powered trials are impossible.
Externí odkaz:
https://doaj.org/article/bca96b408c804f8a8be5102283cb0c34
Autor:
Mouna Akacha, Christian Bartels, Björn Bornkamp, Frank Bretz, Neva Coello, Thomas Dumortier, Michael Looby, Oliver Sander, Heinz Schmidli, Jean‐Louis Steimer, Camille Vong
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 4, Pp 279-282 (2021)
Externí odkaz:
https://doaj.org/article/3b8ad428c84940ed841522ba4471f1f8
Autor:
Camille Vong, Frank Bretz, Thomas Dumortier, Jean-Louis Steimer, Heinz Schmidli, Oliver Sander, Christian Bartels, Neva Coello, Michael Looby, Björn Bornkamp, Mouna Akacha
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 4, Pp 279-282 (2021)
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 4, Pp 279-282 (2021)
Autor:
Thomas Dumortier, Christian Bartels
When constructing models to summarize clinical data to be used for simulations, it is good practice to evaluate the models for their capacity to reproduce the data. This can be done by means of Visual Predictive Checks (VPC), which consist of (1) sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2513b198823c2d59cc62126fef6108ae
Autor:
Nicholas H. G. Holford, Joseph F. Standing, Flora T. Musuamba, Norbert Benda, Andrew C. Hooker, Solange Corriol-Rohou, Frank Bretz, P H van der Graaf, Falk Ehmann, Martin Posch, I. Skottheim Rusten, S. Y. A. Cheung, Bjoern Bornkamp, Lena E. Friberg, Kristin E. Karlsson, James W.T. Yates, Robert Hemmings, A. Brochot, Efthymios Manolis, Neal Thomas, Susan Cole, Shampa Das, F. Serone, Valeria Gigante, Scott Berry, Thomas Dumortier, Justin L. Hay, Kayode Ogungbenro
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:418-429
Inadequate dose selection for confirmatory trials is currently still one of the most challenging issues in drug development, as illustrated by high rates of late-stage attritions in clinical development and postmarketing commitments required by regul
Autor:
Marc Touillier, Morgan Sweeney, Thomas Dumortier, Claire Langlais, Marjolaine Roccati, Jacqueline Domenach, Céline Chassang
Publikováno v:
Revue des droits de l’homme.
Cette cinquième édition de la chronique de droit des discriminations couvre la période du 1er octobre 2016 au 31 mars 2017. Elle rend compte de l’actualité législative et jurisprudentielle relative aux discriminations durant cette période.
Publikováno v:
Revue des droits de l’homme.
Autor:
Thomas Dumortier
Publikováno v:
Archives de politique criminelle. :105
Publikováno v:
Revue des droits de l’homme.