Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Thomas Dresbach"'
Autor:
Nina Wittenmayer, Andonia Petkova-Tuffy, Maximilian Borgmeyer, Chungku Lee, Jürgen Becker, Andreas Böning, Sebastian Kügler, JeongSeop Rhee, Julio S. Viotti, Thomas Dresbach
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Synapse formation is critical for the wiring of neural circuits in the developing brain. The synaptic scaffolding protein S-SCAM/MAGI-2 has important roles in the assembly of signaling complexes at post-synaptic densities. However, the role of S-SCAM
Externí odkaz:
https://doaj.org/article/26ee08b1a7b74c4992e7013016014b28
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-20 (2021)
Abstract Background Maturation is a process that allows synapses to acquire full functionality, optimizing their activity to diverse neural circuits, and defects in synaptic maturation may contribute to neurodevelopmental disorders. Neuroligin-1 (NL1
Externí odkaz:
https://doaj.org/article/ed1fe80f98f94bd1bd5727763d6f0f87
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Bassoon is a core scaffold protein of the presynaptic active zone. In brain synapses, the C-terminus of Bassoon is oriented toward the plasma membrane and its N-terminus is oriented toward synaptic vesicles. At the Golgi-apparatus, Bassoon is thought
Externí odkaz:
https://doaj.org/article/293f35936d2f4672a52f113d0883329e
Autor:
Julio S. Viotti, Thomas Dresbach
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Neurotransmitter release relies on an evolutionarily conserved presynaptic machinery. Nonetheless, some proteins occur in certain species and synapses, and are absent in others, indicating that they may have modulatory roles. How such proteins expand
Externí odkaz:
https://doaj.org/article/442d155aecfe438c9d32c41371b38647
Autor:
Asha Kiran Akula, Xin Zhang, Julio S. Viotti, Dennis Nestvogel, Jeong-Seop Rhee, Rene Ebrecht, Kerstin Reim, Fred Wouters, Thomas Liepold, Olaf Jahn, Ivan Bogeski, Thomas Dresbach
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Neurotransmitter release is mediated by an evolutionarily conserved machinery. The synaptic vesicle (SV) associated protein Mover/TPRGL/SVAP30 does not occur in all species and all synapses. Little is known about its molecular properties and how it m
Externí odkaz:
https://doaj.org/article/bd88b6e42d3c4ddf8e9a60044d777648
Autor:
Rebecca Wallrafen, Thomas Dresbach
Publikováno v:
Frontiers in Neuroanatomy, Vol 12 (2018)
The assembly and function of presynaptic nerve terminals relies on evolutionarily conserved proteins. A small number of presynaptic proteins occurs only in vertebrates. These proteins may add specialized functions to certain synapses, thus increasing
Externí odkaz:
https://doaj.org/article/a162ea9438a344df8fdd5841151eee66
Autor:
Saheeb Ahmed, Nina Wittenmayer, Thomas Kremer, Jan Hoeber, Asha Kiran Akula, Henning Urlaub, Markus Islinger, Joachim Kirsch, Camin Dean, Thomas Dresbach
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63474 (2013)
With remarkably few exceptions, the molecules mediating synaptic vesicle exocytosis at active zones are structurally and functionally conserved between vertebrates and invertebrates. Mover was found in a yeast-2-hybrid assay using the vertebrate-spec
Externí odkaz:
https://doaj.org/article/7731ba30286e4d8585a237756518208c
Autor:
Kai Murk, Nina Wittenmayer, Kristin Michaelsen-Preusse, Thomas Dresbach, Cora-Ann Schoenenberger, Martin Korte, Brigitte M Jockusch, Martin Rothkegel
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34167 (2012)
Profilins are prominent regulators of actin dynamics. While most mammalian cells express only one profilin, two isoforms, PFN1 and PFN2a are present in the CNS. To challenge the hypothesis that the expression of two profilin isoforms is linked to the
Externí odkaz:
https://doaj.org/article/f695321651fe451798eabfcb55de995b
Autor:
Shlomo Tsuriel, Ran Geva, Pedro Zamorano, Thomas Dresbach, Tobias Boeckers, Eckart D Gundelfinger, Craig C Garner, Noam E Ziv
Publikováno v:
PLoS Biology, Vol 4, Iss 9, p e271 (2006)
Recent studies suggest that central nervous system synapses can persist for weeks, months, perhaps lifetimes, yet little is known as to how synapses maintain their structural and functional characteristics for so long. As a step toward a better under
Externí odkaz:
https://doaj.org/article/4196b2ac41d940fd9a9c50c11290575c
Autor:
Eva Maria Schleicher, Thomas A. Bayer, Trendelina Iseni, Frederik Wilhelm Ott, Jannek Moritz Wagner, Julio S. Viotti, Thomas Dresbach, Yvonne Bouter
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11159
The presynaptic protein Mover/TPRGL/SVAP30 is absent in Drosophila and C. elegans and differentially expressed in synapses in the rodent brain, suggesting that it confers specific functions to subtypes of presynaptic terminals. In order to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964d5c03ae08100618a1157d08b55250