Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling.

Autor: Marc J Geisen, Thomas Di Meglio, Massimo Pasqualetti, Sebastien Ducret, Jean-François Brunet, Alain Chedotal, Filippo M Rijli

Publikováno v: PLoS Biology, Vol 6, Iss 6, p e142 (2008)

The pontine neurons (PN) represent a major source of mossy fiber projections to the cerebellum. During mouse hindbrain development, PN migrate tangentially and sequentially along both the anteroposterior (AP) and dorsoventral (DV) axes. Unlike DV mig

Externí odkaz: https://doaj.org/article/052b264d8bfc46df8ab405ecad8938da

Hox2 Genes Are Required for Tonotopic Map Precision and Sound Discrimination in the Mouse Auditory Brainstem

Autor: Alberto Loche, Thomas Di Meglio, Joao Bacelo, Filippo M. Rijli, Andreas Lüthi, Sebastien Ducret, Jonathan P. Fadok, Raphael Thierry, Christel Genoud, Yuichi Narita, Kajari Karmakar, Taro Kitazawa

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Tonotopy is a hallmark of auditory pathways and provides the basis for sound discrimination. Little is known about the involvement of transcription factors in brainstem cochlear neurons orchestrating the tonotopic precision of pre-synaptic input. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e9c06aa9429a3695e893dc78a2342a
http://hdl.handle.net/10261/166130

The Role of Robo3 in the Development of Cortical Interneurons

Autor: Fujio Murakami, John G. Parnavelas, Thomas Di Meglio, Alain Chédotal, Melissa Barber, William Andrews, Luis R. Hernández-Miranda

Publikováno v: Cerebral Cortex (New York, NY)

A number of studies in recent years have shown that members of the Roundabout (Robo) receptor family, Robo1 and Robo2, play significant roles in the formation of axonal tracks in the developing forebrain and in the migration and morphological differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29a224e2df14b018148a88b1b7e3ab3
https://doi.org/10.1093/cercor/bhp041

Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons

Autor: Filippo M. Rijli, Antonio Vitobello, Steven M. Hrycaj, Alberto Loche, Thomas Di Meglio, Antoine H.F.M. Peters, Claudius F. Kratochwil, Deneen M. Wellik, Anne Eichmann, Keisuke Yonehara, Sebastien Ducret, Botond Roska, Nathalie Vilain

Publikováno v: SCIENCE
Di Meglio, T, Kratochwil, C F, Vilain, N, Loche, A, Vitobello, A, Yonehara, K, Hrycaj, S M, Roska, B, Peters, A H F M, Eichmann, A, Wellik, D, Ducret, S & Rijli, F M 2013, ' Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons ', Science, vol. 339, no. 6116, pp. 204-7 . https://doi.org/10.1126/science.1229326
Science

Destination Specificity During brain development, some types of neurons migrate from where they are born to their final functional locations. Some neurons migrate radially, from the inside to the outside, while others migrate tangentially. Di Meglio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa39fee8cb6d1349aacbefa87e1340a
https://pubmed.ncbi.nlm.nih.gov/23307742

Molecular mechanisms controlling midline crossing by precerebellar neurons

Autor: Thomas Di Meglio, Kim T. Nguyen-Ba-Charvet, Constantino Sotelo, Alain Chédotal, Marc Tessier-Lavigne

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2008, 28 (25), pp.6285-94. ⟨10.1523/JNEUROSCI.0078-08.2008⟩
Journal of Neuroscience, 2008, 28 (25), pp.6285-94. ⟨10.1523/JNEUROSCI.0078-08.2008⟩

Precerebellar neurons of the inferior olive (IO) and lateral reticular nucleus (LRN) migrate tangentially from the rhombic lip toward the floor plate following parallel pathways. This process is thought to involve netrin-1 attraction. However, wherea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614af54987c68949c4e61a69c1b537c7
http://hdl.handle.net/10261/62406