Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Thomas Dequesne"'
Autor:
Nicolas Merienne, Gabriel Vachey, Lucie de Longprez, Cécile Meunier, Virginie Zimmer, Guillaume Perriard, Mathieu Canales, Amandine Mathias, Lucas Herrgott, Tim Beltraminelli, Axelle Maulet, Thomas Dequesne, Catherine Pythoud, Maria Rey, Luc Pellerin, Emmanuel Brouillet, Anselme L. Perrier, Renaud du Pasquier, Nicole Déglon
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2980-2991 (2017)
Neurodegenerative disorders are a major public health problem because of the high frequency of these diseases. Genome editing with the CRISPR/Cas9 system is making it possible to modify the sequence of genes linked to these disorders. We designed the
Externí odkaz:
https://doaj.org/article/c95c2641b9a34acb9503af6deab5c2eb
Autor:
Nicolas Merienne, Gabriel Vachey, Lucie de Longprez, Cécile Meunier, Virginie Zimmer, Guillaume Perriard, Mathieu Canales, Amandine Mathias, Lucas Herrgott, Tim Beltraminelli, Axelle Maulet, Thomas Dequesne, Catherine Pythoud, Maria Rey, Luc Pellerin, Emmanuel Brouillet, Anselme L. Perrier, Renaud du Pasquier, Nicole Déglon
Publikováno v:
Cell reports, vol. 20, no. 12, pp. 2980-2991
Cell Reports, Vol 20, Iss 12, Pp 2980-2991 (2017)
Cell Reports, Vol 20, Iss 12, Pp 2980-2991 (2017)
Neurodegenerative disorders are a major public health problem because of the high frequency of these diseases. Genome editing with the CRISPR/Cas9 system is making it possible to modify the sequence of genes linked to these disorders. We designed the
Autor:
Nicole Déglon, Cécile Meunier, Maria Rey, Virginie Zimmer, Gabriel Vachey, Guillaume Perriard, Renaud Du Pasquier, Catherine Pythoud, Lucas Hergott, Tim Beltraminelli, Anselme L. Perrier, Luc Pellerin, Mathieu Canales, Thomas Dequesne
Publikováno v:
Molecular Therapy. 24:S131
Huntington's disease (HD) is a neurodegenerative disorder caused by a pathological CAG expansion at the 3’ end of the first exon of the huntingtin gene (HTT). Currently, there is no efficient treatment for HD. Editing of the mutant HTT gene with th