NCS1 overexpression restored mitochondrial activity and behavioral alterations in a zebrafish model of Wolfram syndrome

Autor: Lucie Crouzier, Elodie M. Richard, Camille Diez, Morgane Denus, Amandine Peyrel, Hala Alzaeem, Nicolas Cubedo, Thomas Delaunay, Tangui Maurice, Benjamin Delprat

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 295-308 (2022)

Wolfram syndrome (WS) is a rare neurodegenerative disease resulting in deafness, optic atrophy, diabetes, and neurological disorders. Currently, no treatment is available for patients. The mutated gene, WFS1, encodes an endoplasmic reticulum (ER) pro

Externí odkaz: https://doaj.org/article/8a0f00345eee450bbc8aff2f87918237

Morphological, behavioral and cellular analyses revealed different phenotypes in Wolfram syndrome wfs1a and wfs1b zebrafish mutant lines

Autor: Lucie Crouzier, Elodie M Richard, Camille Diez, Hala Alzaeem, Morgane Denus, Nicolas Cubedo, Thomas Delaunay, Emily Glendenning, Sarah Baxendale, Jean-Charles Liévens, Tanya T Whitfield, Tangui Maurice, Benjamin Delprat

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, 2022, 31 (16), pp.2711-2727. ⟨10.1093/hmg/ddac065⟩

Wolfram syndrome (WS) is a rare genetic disease characterized by diabetes, optic atrophy and deafness. Patients die at 35 years of age, mainly from respiratory failure or dysphagia. Unfortunately, there is no treatment to block the progression of sym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264676d4c05fd25524ac45972707366f
https://hal.umontpellier.fr/hal-03757700

Electrical admittance of piezoelectric parallelepipeds: application to tensorial characterization of piezoceramics

Autor: Oumar Diallo, Thomas Delaunay, Emmanuel Le Clézio, Guy Feuillard, Maxime Bavencoffe

Publikováno v: AIP Advances
AIP Advances, American Institute of Physics-AIP Publishing LLC, 2014, 4 (1), 〈10.1063/1.4863090〉
AIP Advances, American Institute of Physics-AIP Publishing LLC, 2014, 4 (1), ⟨10.1063/1.4863090⟩
AIP Advances, Vol 4, Iss 1, Pp 017121-017121-13 (2014)

International audience; This work deals with the characterization of functional properties, including determination of mechanical and electrical losses, of piezoelectric materials using only one sample and one measurement. First, the natural resonant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b694e52233c15857652846e2ee8ad
https://hal.archives-ouvertes.fr/hal-01627806

Milli-PIV rheology of shear-thinning fluids

Autor: Sébastien Cazin, Philippe Tordjeman, Emmanuel Cid, Maxime Chinaud, Thomas Delaunay

Publikováno v: Journal of Non-Newtonian Fluid Mechanics
Journal of Non-Newtonian Fluid Mechanics, Elsevier, 2012, vol. 169-170, pp. 114-120. ⟨10.1016/j.jnnfm.2011.12.003⟩

International audience; Milli-Particle Image Velocimetry (Milli-PIV), which is an application of the standard PIV has been developed to measure the velocity distribution of complex fluids in a millimetric Hele-Shaw cell. A laser sheet is sent perpend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b545255a53dcf07809b3937f7730b4
https://oatao.univ-toulouse.fr/10099/

Relations between single-domain and multidomain piezoelastic properties in single crystals

Autor: Guy Feuillard, Thomas Delaunay, M. Lematre, E. Le Clezio

Publikováno v: IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, Institute of Electrical and Electronics Engineers, 2006, 53 (11), pp.1974-1981. ⟨10.1109/TUFFC.2006.137⟩

This paper presents a new method to compute the piezoelastic properties of multidomain single crystals from the single-domain constants. Based on a quasi static assumption, a PMN-chiPT multidomain is defined as a periodic medium with a lattice compos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7eebae2f6804ee0b1e89ae6ded43f5
https://pubmed.ncbi.nlm.nih.gov/17091833