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pro vyhledávání: '"Thomas Decoene"'
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224476 (2019)
Altering gene expression regulation by promoter engineering is a very effective way to fine-tune heterologous pathways in eukaryotic hosts. Typically, pathway building approaches in yeast still use a limited set of long, native promoters. With the to
Externí odkaz:
https://doaj.org/article/7f79f87851cc48d5b57b4150fba9ff88
Publikováno v:
ACS Synthetic Biology. 7:622-634
Fine-tuning biosynthetic pathways is crucial for the development of economic feasible microbial cell factories. Therefore, the use of computational models able to predictably design regulatory sequences for pathway engineering proves to be a valuable
Autor:
Thomas Decoene, Pieter Coussement, Brecht De Paepe, Sofie De Maeseneire, Jo Maertens, Marjan De Mey, Gert Peters
Publikováno v:
Critical reviews in biotechnology. 38(5)
Leaping DNA read-and-write technologies, and extensive automation and miniaturization are radically transforming the field of biological experimentation by providing the tools that enable the cost-effective high-throughput required to address the eno