Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Thomas De Beer"'
Autor:
Luz Nadiezda Naranjo Gómez, Kensaku Matsunami, Paul Van Liedekerke, Thomas De Beer, Ashish Kumar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract In continuous powder handling processes, precise and consistent feeding is crucial for ensuring the quality of the final product. The intermixing effect caused by agitators, which alters the powder’s bulk density, flow rate, and flow patte
Externí odkaz:
https://doaj.org/article/1517ac00993d42e2bd16ceb582bb6ce7
Autor:
Tuur Vandeputte, Michael Ghijs, Michiel Peeters, Alexander De Man, Daan Van Hauwermeiren, Eduardo Dos Santos Schultz, Tamas Vigh, Fanny Stauffer, Ingmar Nopens, Thomas De Beer
Publikováno v:
Powders, Vol 2, Iss 2, Pp 232-258 (2023)
In the last decade, twin-screw wet granulation became an essential technology for continuous pharmaceutical tablet production. Consequently, interest in (semi-)continuous fluidized bed drying systems as a subsequent processing unit has grown. In para
Externí odkaz:
https://doaj.org/article/5e6b4748dfd44e028db64a6c67cbf98a
Autor:
Tryfon Digkas, Alina Porfire, Jeroen Van Renterghem, Aseel Samaro, Gheorghe Borodi, Chris Vervaet, Andrea Gabriela Crișan, Sonia Iurian, Thomas De Beer, Ioan Tomuta
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1062 (2023)
The present study aimed to develop 3D printed dosage forms, using custom-made filaments loaded with diclofenac sodium (DS). The printed tablets were developed by implementing a quality by design (QbD) approach. Filaments with adequate FDM 3D printing
Externí odkaz:
https://doaj.org/article/79bf6d34b8734f32b2c23a73597116f7
Autor:
Christoph Portier, Tamas Vigh, Giustino Di Pretoro, Jan Leys, Didier Klingeleers, Thomas De Beer, Chris Vervaet, Valérie Vanhoorne
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100077- (2021)
Despite significant advances in the research domain of continuous twin screw granulation, limited information is currently available on the impact of raw material properties, especially considering batch-to-batch variability. The importance of raw ma
Externí odkaz:
https://doaj.org/article/7b5b47b81cd84b6d90d660515d4b07d0
The large N limit of OPEs in symmetric orbifold CFTs with N $$ \mathcal{N} $$ = (4, 4) supersymmetry
Publikováno v:
Journal of High Energy Physics, Vol 2019, Iss 8, Pp 1-39 (2019)
Abstract We explore the OPE of certain twist operators in symmetric product (S N ) orbifold CFTs, extending our previous work [1] to the case of N $$ \mathcal{N} $$ = (4, 4) supersymmetry. We consider a class of twist operators related to the chiral
Externí odkaz:
https://doaj.org/article/80257cb54b3b4e22b43a8d813ba80199
Autor:
Edward Geeurickx, Joeri Tulkens, Bert Dhondt, Jan Van Deun, Lien Lippens, Glenn Vergauwen, Elisa Heyrman, Delphine De Sutter, Kris Gevaert, Francis Impens, Ilkka Miinalainen, Pieter-Jan Van Bockstal, Thomas De Beer, Marca H. M. Wauben, Esther N. M. Nolte-‘t-Hoen, Katarzyna Bloch, Johannes V. Swinnen, Edwin van der Pol, Rienk Nieuwland, Geert Braems, Nico Callewaert, Pieter Mestdagh, Jo Vandesompele, Hannelore Denys, Sven Eyckerman, Olivier De Wever, An Hendrix
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
There is no universal reference material to develop extracellular vesicle (EV) separation methods and carry out calibration and normalization. Here the authors use HIV-derived gag proteins to assemble recombinant fluorescent EV as a trackable referen
Externí odkaz:
https://doaj.org/article/07dfa2e581d14bf79f66bb78fe9a3cd4
Autor:
Brecht Vanbillemont, Thomas De Beer
Publikováno v:
International Journal of Pharmaceutics: X, Vol 2, Iss , Pp 100057- (2020)
Oral lyophilizates also called orally disintegrating tablets (ODTs) are a patient friendly and convenient dosage form. They are manufactured by dosing a suspension in blister cups and subsequently freeze-drying these blisters to achieve porous tablet
Externí odkaz:
https://doaj.org/article/14ab8062f4e14c82b4b9e7ac1749e0f3
Autor:
Gust Nuytten, Susan Ríos Revatta, Pieter-Jan Van Bockstal, Ashish Kumar, Joris Lammens, Laurens Leys, Brecht Vanbillemont, Jos Corver, Chris Vervaet, Thomas De Beer
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2076 (2021)
During the spin freezing step of a recently developed continuous spin freeze-drying technology, glass vials are rapidly spun along their longitudinal axis. The aqueous drug formulation subsequently spreads over the inner vial wall, while a cold gas f
Externí odkaz:
https://doaj.org/article/8426039a85ab42959ba7b16b7114420a
Autor:
Laurens Leys, Gust Nuytten, Joris Lammens, Pieter-Jan Van Bockstal, Jos Corver, Chris Vervaet, Thomas De Beer
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2168 (2021)
The pharmaceutical industry is progressing toward the development of more continuous manufacturing techniques. At the same time, the industry is striving toward more process understanding and improved process control, which requires the implementatio
Externí odkaz:
https://doaj.org/article/6fad6831d9274b0eae4b56f08186be39
Autor:
Joris Lammens, Niloofar Moazami Goudarzi, Laurens Leys, Gust Nuytten, Pieter-Jan Van Bockstal, Chris Vervaet, Matthieu N. Boone, Thomas De Beer
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2126 (2021)
Spin freeze-drying, as a part of a continuous freeze-drying technology, is associated with a much higher drying rate and a higher level of process control in comparison with batch freeze-drying. However, the impact of the spin freezing rate on the dr
Externí odkaz:
https://doaj.org/article/7656bbca8fb642298bc91698c967d840