Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thomas D.L. Steeves"'
Autor:
Miracle Ozzoude, Brenda Varriano, Derek Beaton, Joel Ramirez, Sabrina Adamo, Melissa F. Holmes, Christopher J.M. Scott, Fuqiang Gao, Kelly M. Sunderland, Paula McLaughlin, Maged Goubran, Donna Kwan, Angela Roberts, Robert Bartha, Sean Symons, Brian Tan, Richard H. Swartz, Agessandro Abrahao, Gustavo Saposnik, Mario Masellis, Anthony E. Lang, Connie Marras, Lorne Zinman, Christen Shoesmith, Michael Borrie, Corinne E. Fischer, Andrew Frank, Morris Freedman, Manuel Montero-Odasso, Sanjeev Kumar, Stephen Pasternak, Stephen C. Strother, Bruce G. Pollock, Tarek K. Rajji, Dallas Seitz, David F. Tang-Wai, John Turnbull, Dar Dowlatshahi, Ayman Hassan, Leanne Casaubon, Jennifer Mandzia, Demetrios Sahlas, David P. Breen, David Grimes, Mandar Jog, Thomas D.L. Steeves, Stephen R. Arnott, Sandra E. Black, Elizabeth Finger, Jennifer Rabin, ONDRI Investigators, Maria Carmela Tartaglia
Background: Neuropsychiatric symptoms (NPS) are a core feature of most neurodegenerative and cerebrovascular diseases. White matter hyperintensities and brain atrophy have been implicated in NPS. We aimed to investigate the relative contribution of w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2631852c45792e122a7ed198ca6ee83
https://doi.org/10.21203/rs.3.rs-2062160/v1
https://doi.org/10.21203/rs.3.rs-2062160/v1
Autor:
Thomas D.L. Steeves, David Staknis, Karen Wager-Smith, Charles J. Weitz, Joseph S. Takahashi, Thomas K. Darlington, Nicholas Gekakis, Steve A. Kay, M. Fernanda Ceriani
Publikováno v:
Science. 280:1599-1603
The circadian oscillator generates a rhythmic output with a period of about 24 hours. Despite extensive studies in several model systems, the biochemical mode of action has not yet been demonstrated for any of its components. Here, the Drosophila CLO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd06950cefe3b3f308b71fa2fa3e62ca
https://doi.org/10.1126/science.280.5369.1599
https://doi.org/10.1126/science.280.5369.1599
Autor:
Yaliang Zhao, Fred W. Turek, Lisa D. Wilsbacher, Martha Hotz Vitaterna, David P. King, Thomas D.L. Steeves, Minoru Tanaka, Joseph S. Takahashi, Marina P. Antoch, Phillip L. Lowrey, Jon M. Kornhauser, Ashvin M. Sangoram
Publikováno v:
Cell. 89:641-653
We used positional cloning to identify the circadian Clock gene in mice. Clock is a large transcription unit with 24 exons spanning approximately 100,000 bp of DNA from which transcript classes of 7.5 and approximately 10 kb arise. Clock encodes a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31415039c5596fddf68778c99faedce5
https://doi.org/10.1016/s0092-8674(00)80245-7
https://doi.org/10.1016/s0092-8674(00)80245-7
Publikováno v:
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 14(4)
Phosphodiesterase type 5 (PDE 5) inhibitors are widely used in the treatment of erectile dysfunction. However, the results on the cerebral vasculature are unknown. Several cases of intraparenchymal hemorrhage in the setting of PDE 5 inhibitor use hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8c33bbefba776aa3e36a3904a6e9c6
https://pubmed.ncbi.nlm.nih.gov/17904022
https://pubmed.ncbi.nlm.nih.gov/17904022
Autor:
Martha Hotz Vitaterna, Andrew R. Whiteley, Jani Kushla, Joseph S. Takahashi, Peter D. Zemenides, Thomas D.L. Steeves, David P. King, Andrew Lin, Gary A. Churchill, Sharon S. Low-Zeddies, Kazuhiro Shimomura
Publikováno v:
Genome research. 11(6)
Genetic heterogeneity underlies many phenotypic variations observed in circadian rhythmicity. Continuous distributions in measures of circadian behavior observed among multiple inbred strains of mice suggest that the inherent contributions to variabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aea7585d7010e9d517ddb526927cfcc
https://pubmed.ncbi.nlm.nih.gov/11381025
https://pubmed.ncbi.nlm.nih.gov/11381025
Autor:
Andrew R. Whiteley, Carla B. Green, Joseph S. Takahashi, Thomas D.L. Steeves, Haisun Zhu, Silvia I. LaRue
Publikováno v:
Brain research. Molecular brain research. 75(2)
Many aspects of normal retinal physiology are controlled by a retinal circadian clock. In Xenopus laevis, the photoreceptor cells within the retina contain a circadian clock that controls melatonin release. In this report we present the cloning and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44c5762ce33a81e04bea530c68f4216
https://pubmed.ncbi.nlm.nih.gov/10686352
https://pubmed.ncbi.nlm.nih.gov/10686352
Autor:
Robert Y. Moore, Anne M. Bowcock, David P. King, Joseph S. Takahashi, Ashvin M. Sangoram, Fenghe Du, Yaliang Zhao, Thomas D.L. Steeves
Publikováno v:
Genomics. 57(2)
The Clock gene is an essential regulator of circadian rhythms. It encodes a member of the basic helix-loop-helix/PER-ARNT-SIM family of transcription factors known to play a central role in the control of diverse cellular events. Previously we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0a331607fe142b2a51b06faa539126
https://pubmed.ncbi.nlm.nih.gov/10198158
https://pubmed.ncbi.nlm.nih.gov/10198158