Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Thomas D. Scholz"'
Autor:
Erin K. Zinkhan, Qi Fu, Yan Wang, Xing Yu, Christopher W. Callaway, Jeffrey L. Segar, Thomas D. Scholz, Robert A. McKnight, Lisa Joss-Moore, Robert H. Lane
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2012 (2012)
In utero environmental adaptation may predispose to lifelong morbidity. Organisms fine-tune gene expression to achieve environmental adaptation by epigenetic alterations of histone markers of gene accessibility. One example of epigenetics is how uter
Externí odkaz:
https://doaj.org/article/caf70969dc6b4b4586873cce8ab2b7e7
Autor:
Kristin, Palmsten, Jonathan, Suhl, Kristin M, Conway, Elyse O, Kharbanda, Thomas D, Scholz, Elizabeth C, Ailes, Janet D, Cragan, Eirini, Nestoridi, Eleni A, Papadopoulos, Stephen M, Kerr, Sean G, Young, Christine, Olson, Paul A, Romitti
Publikováno v:
Birth Defects Research. 115:88-95
Although results from studies of first-trimester influenza vaccination and congenital heart defects (CHDs) have been reassuring, data are limited for specific CHDs.We assessed associations between reported maternal influenza vaccination, 1 month befo
Autor:
Jonathan, Suhl, Kristin M, Conway, Anthony, Rhoads, Peter H, Langlois, Marcia L, Feldkamp, Adrian M, Michalski, Jacob, Oleson, Alpa, Sidhu, Thomas D, Scholz, Vijaya, Kancherla, John, Obrycki, Maitreyi, Mazumdar, Paul A, Romitti
Publikováno v:
Birth Defects Research. 115:79-87
Arsenic crosses the placenta and accumulates in fetal tissues. In the United States, diet is the predominant route of arsenic exposure, but epidemiologic data are sparse regarding this exposure and development of birth defects. Using data from a larg
Autor:
Alyson R. Pierick, Trudy A. Pierick, Thomas D. Scholz, M. Bridget Zimmerman, Benjamin E. Reinking
Publikováno v:
Cardiology in the Young. 32:1999-2004
Background:Hypoplastic left heart syndrome and single ventricle variants with aortic hypoplasia are commonly classified as severe forms of CHD. We hypothesised patients with these severe defects and reported genetic abnormalities have increased morbi
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 308:R965-R972
ANG II increases fetal blood pressure and stimulates fetal heart growth; however, little is known regarding its direct effects on cardiomyocytes in vivo. We sought to determine whether ANG II stimulates heart growth and cardiomyocyte hypertrophy and/
Autor:
Ken A. Volk, Jeffrey L. Segar, Andrew W. Norris, Emily S. Peterson, Thomas D. Scholz, Timothy M. Bahr
Publikováno v:
Pediatric research
Background Angiotensin II (ANG II) stimulates fetal heart growth, though little is known regarding changes in cardiomyocyte endowment or the molecular pathways mediating the response. We measured cardiomyocyte proliferation and morphology in ANG II t
Publikováno v:
Catheterization and Cardiovascular Interventions. 81:1008-1012
Guidelines for the treatment of active right-sided endocarditis are not well defined. We report the first novel use of an aspiration catheter system for transcatheter therapy of refractory active right sided endocarditis on a bioprosthetic valve in a
Publikováno v:
Experimental Physiology. 98:722-733
Thyroid hormone exerts broad effects on the adult heart, but little is known regarding the role of thyroid hormone in the regulation of cardiac growth early in development and in response to pathophysiological conditions. To address this issue, we de
Autor:
Stefan Strack, Mark E. Anderson, Jinying Yang, Thomas D. Scholz, Olha M. Koval, Biyi Chen, Steven A. Moore, Long-Sheng Song, Duane D. Hall, Jingdong Li, B. Julie He, Zhan Gao, William I. Sivitz, Elizabeth D. Luczak, Mei Ling A. Joiner, Peter J. Mohler, Chantal Allamargot, Brian D. Fink
Publikováno v:
Nature
Myocardial cell death is initiated by excessive mitochondrial Ca(2+) entry causing Ca(2+) overload, mitochondrial permeability transition pore (mPTP) opening and dissipation of the mitochondrial inner membrane potential (ΔΨm). However, the signalli
Maternal antioxidant blocks programmed cardiovascular and behavioural stress responses in adult mice
Autor:
Fred S. Lamb, Thomas D. Scholz, Kenneth A. Volk, Robert D. Roghair, Jeffrey L. Segar, John A. Wemmie
Publikováno v:
Clinical Science. 121:427-436
Intra-uterine growth restriction is an independent risk factor for adult psychiatric and cardiovascular diseases. In humans, intra-uterine growth restriction is associated with increased placental and fetal oxidative stress, as well as down-regulatio