Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Thomas D. Sargent"'
Autor:
Sheran H W Law, Thomas D Sargent
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100268 (2014)
TALEN-based inactivation of the zebrafish pak4 gene resulted in embryos and adult fish that appear normal and fertile. This is in contrast to our previously published studies which were based on the use of antisense morpholino oligonucleotides (MOs).
Externí odkaz:
https://doaj.org/article/9f894bbe4c424a67881affe81934099d
Autor:
Sheran H.W. Law, Thomas D. Sargent
Publikováno v:
Mechanisms of Development. 130:181-194
Transcripts of pak4, the zebrafish ortholog of p21-activated kinase 4 (PAK4), are most abundant in the egg and fall to low levels by the end of gastrulation, after which expression is essentially ubiquitous. Translation of maternal mRNA into pak4 pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2642d63ceba986db8c9525682a389840
https://doi.org/10.1016/j.mod.2012.09.005
https://doi.org/10.1016/j.mod.2012.09.005
Publikováno v:
Developmental Dynamics. 239:1188-1196
Previous studies identified Inka1 as a gene regulated by AP-2alpha in the neural crest required for craniofacial morphogenesis in fish and frog. Here, we extend the analysis of Inka1 function and regulation to the mouse by generating a LacZ knock-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503886f1caf49fae1323592967eff2c2
https://doi.org/10.1002/dvdy.22248
https://doi.org/10.1002/dvdy.22248
Publikováno v:
Developmental Dynamics. 238:2522-2529
Myosin-X (MyoX) belongs to a large family of unconventional, nonmuscle, actin-dependent motor proteins. We show that MyoX is predominantly expressed in cranial neural crest (CNC) cells in embryos of Xenopus laevis and is required for head and jaw car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572acf07f486a8a66a514040c24ebc1f
https://doi.org/10.1002/dvdy.22077
https://doi.org/10.1002/dvdy.22077
Publikováno v:
Gene Expression Patterns. 6:589-595
The embryonic expression patterns of two additional members of the transcription factor TFAP2 family in Xenopus laevis, TFAP2beta and TFAP2gamma, are described. Both genes share overlapping expression domains with the previously characterized TFAP2al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d138e648b0204d0553cf5a106a99976b
https://doi.org/10.1016/j.modgep.2005.11.011
https://doi.org/10.1016/j.modgep.2005.11.011
Publikováno v:
Developmental Biology. 295(1):206-218
Protocadherins (Pcdhs), a major subfamily of cadherins, play an important role in specific intercellular interactions in development. These molecules are characterized by their unique extracellular domain (EC) with more than 5 cadherin-like repeats,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30769debdf2430ee9c0225814226811d
Publikováno v:
The International Journal of Developmental Biology. 49:981-984
Dysregulation of Fragile X mental retardation-1 (Fmr1) gene expression results in an inherited form of mental retardation known as the Fragile X syndrome (FXS). Fmr1 is a highly conserved gene with a broad yet distinctive expression pattern during ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0219a8aa3f0d3146c16e98cfd0cf6581
https://doi.org/10.1387/ijdb.052070jl
https://doi.org/10.1387/ijdb.052070jl
Autor:
Maureen J Beanan, Thomas D. Sargent
Publikováno v:
Developmental Dynamics. 218:545-553
Dlx3 is a homeodomain transcription factor in vertebrates, related to Distal-less in Drosophila, that is expressed in differentiating epidermal cells, in neural crest, hair follicles, dental epithelium and mesenchyme, the otic and olfactory placodes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::472e4ead3ecc46d4d927239dc66b60d9
https://doi.org/10.1002/1097-0177(2000)9999:9999<::aid-dvdy1026>3.0.co
https://doi.org/10.1002/1097-0177(2000)9999:9999<::aid-dvdy1026>3.0.co
Autor:
Jennifer S Goodrich, Mami Matsuo-Takasaki, Sheryl M. Sato, Jules A Feledy, Maureen J Beanan, Thomas D. Sargent, Jae H Lim, John J Sandoval
Publikováno v:
Developmental Biology. 212(2):455-464
Patterning of the embryonic ectoderm is dependent upon the action of negative (antineural) and positive (neurogenic) transcriptional regulators. Msx1 and Dlx3 are two antineural genes for which the anterior epidermal–neural boundaries of expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9194aa4717982a754947877ef857cd84
Publikováno v:
Developmental Biology. 179:309-319
Pagliaccio (Pag) is a receptor tyrosine kinase of the Eph family that is expressed inXenopusembryos in a diverse set of localized tissues. Pag is theXenopushomolog of Hek-8 (human), Sek-1 (mouse), cek8 (chicken), and RTK-1 (zebrafish). We have invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873d7b02160692bfbf0e92231f0ac2cf
https://doi.org/10.1006/dbio.1996.0262
https://doi.org/10.1006/dbio.1996.0262