Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thomas D. Prévot"'
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 38, Iss , Pp 100761- (2024)
Inflammation, reduced gamma-aminobutyric acidergic (GABAergic) function and altered neuroplasticity are co-occurring pathophysiologies in major depressive disorder (MDD). However, the link between these biological changes remains unclear. We hypothes
Externí odkaz:
https://doaj.org/article/4837eb1df0ff49c2a3d44a7fcfecf24c
Autor:
Alexandre Guet-McCreight, Homeira Moradi Chameh, Frank Mazza, Thomas D. Prevot, Taufik A. Valiante, Etienne Sibille, Etay Hay
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Reduced inhibition by somatostatin-expressing interneurons is associated with depression. Administration of positive allosteric modulators of α5 subunit-containing GABAA receptor (α5-PAM) that selectively target this lost inhibition exhibi
Externí odkaz:
https://doaj.org/article/dc686f02d621430eacfbf2ab601663ad
Autor:
Ravinder Naik Dharavath, Celeste Pina-Leblanc, Victor M. Tang, Matthew E. Sloan, Yuliya S. Nikolova, Peter Pangarov, Anthony C. Ruocco, Kevin Shield, Daphne Voineskos, Daniel M. Blumberger, Isabelle Boileau, Nikki Bozinoff, Philip Gerretsen, Erica Vieira, Osnat C. Melamed, Etienne Sibille, Lena C. Quilty, Thomas D. Prevot
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Alcohol is one of the most widely used substances. Alcohol use accounts for 5.1% of the global disease burden, contributes substantially to societal and economic costs, and leads to approximately 3 million global deaths yearly. Alcohol use disorder (
Externí odkaz:
https://doaj.org/article/3d71423280734b9381c1657b86041ec5
Autor:
Stephanie M. Perez, Alexandra M. McCoy, Thomas D. Prevot, Md Yeunus Mian, Flavia R. Carreno, Alan Frazer, James M. Cook, Etienne Sibille, Daniel J. Lodge
Publikováno v:
Biological Psychiatry Global Open Science, Vol 3, Iss 1, Pp 78-86 (2023)
Background: Aberrant dopamine neuron activity is attributable to hyperactivity in hippocampal subfields driving a pathological increase in dopamine neuron activity, which is positively correlated with psychosis in humans. Evidence indicates that hipp
Externí odkaz:
https://doaj.org/article/084ff4c6137d42009c20604b31e46173
Autor:
Kevan P. Clifford, Amy E. Miles, Thomas D. Prevot, Keith A. Misquitta, Jacob Ellegood, Jason P. Lerch, Etienne Sibille, Yuliya S. Nikolova, Mounira Banasr
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionAs the population skews toward older age, elucidating mechanisms underlying human brain aging becomes imperative. Structural MRI has facilitated non-invasive investigation of lifespan brain morphology changes, yet this domain remains unch
Externí odkaz:
https://doaj.org/article/94abd58255c441f4af8b8292591b2ad4
Autor:
Alexandra M. McCoy, Thomas D. Prevot, Dishary Sharmin, James M. Cook, Etienne L. Sibille, Daniel J. Lodge
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11588 (2023)
Although seizures are a hallmark feature of temporal lobe epilepsy (TLE), psychiatric comorbidities, including psychosis, are frequently associated with TLE and contribute to decreased quality of life. Currently, there are no defined therapeutic prot
Externí odkaz:
https://doaj.org/article/5431d54356ae4830ad503389385e3291
Autor:
Dishary Sharmin, Md Yeunus Mian, Michael Marcotte, Thomas D. Prevot, Etienne Sibille, Jeffrey M. Witkin, James M. Cook
Publikováno v:
Molecules, Vol 28, Iss 12, p 4771 (2023)
GABA mediates inhibitory actions through various GABAA receptor subtypes, including 19 subunits in human GABAAR. Dysregulation of GABAergic neurotransmission is associated with several psychiatric disorders, including depression, anxiety, and schizop
Externí odkaz:
https://doaj.org/article/acec2607b20b4845bf8d9d92e46a9997
Autor:
Fabrizio Grieco, Briana J. Bernstein, Barbara Biemans, Lior Bikovski, C. Joseph Burnett, Jesse D. Cushman, Elsbeth A. van Dam, Sydney A. Fry, Bar Richmond-Hacham, Judith R. Homberg, Martien J. H. Kas, Helmut W. Kessels, Bastijn Koopmans, Michael J. Krashes, Vaishnav Krishnan, Sreemathi Logan, Maarten Loos, Katharine E. McCann, Qendresa Parduzi, Chaim G. Pick, Thomas D. Prevot, Gernot Riedel, Lianne Robinson, Mina Sadighi, August B. Smit, William Sonntag, Reinko F. Roelofs, Ruud A.J. Tegelenbosch, Lucas P.J.J. Noldus
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
The reproducibility crisis (or replication crisis) in biomedical research is a particularly existential and under-addressed issue in the field of behavioral neuroscience, where, in spite of efforts to standardize testing and assay protocols, several
Externí odkaz:
https://doaj.org/article/e6fe0375a48847e8ab15ebea282102ec
Autor:
Guanguan Li, Michael R. Stephen, Revathi Kodali, Nicolas M. Zahn, Michael M. Poe, V. V. N. Phani Babu Tiruveedhula, Alec T. Huber, Melissa K. Schussman, Krista Qualmann, Cristina M. Panhans, Nicholas J. Raddatz, David A. Baker, Thomas D. Prevot, Mounira Banasr, Etienne Sibille, Leggy A. Arnold, James M. Cook
Publikováno v:
ARKIVOC, Vol 2018, Iss 4, Pp 158-182 (2018)
Externí odkaz:
https://doaj.org/article/f6c4d0576c1d4e9fab7e1fad18c61994
Autor:
Alfred M. Maluach, Keith A. Misquitta, Thomas D. Prevot, Corey Fee, Etienne Sibille, Mounira Banasr, Ana C. Andreazza
Publikováno v:
Chronic Stress, Vol 1 (2017)
Background Chronic stress is implicated in the development of various psychiatric illnesses including major depressive disorder. Previous reports suggest that patients with major depressive disorder have increased levels of oxidative stress, includin
Externí odkaz:
https://doaj.org/article/6d0ff04491fe46519ec74dbc685d17cd