Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas D. McCaffery"'
Autor:
Silke Nuber, Xiaoqun Zhang, Thomas D. McCaffery, Tim E. Moors, Marie-Alexandre Adom, Wolf N. Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J. Selkoe
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Mutations in the α-Synuclein (αS) gene promote αS monomer aggregation that causes neurodegeneration in familial Parkinson’s disease (fPD). However, most mouse models expressing single-mutant αS transgenes develop neuronal aggregates ve
Externí odkaz:
https://doaj.org/article/352db539d02c431293173a6ee8a2d72f
Autor:
Silke Nuber, Xiaoqun Zhang, Thomas D. McCaffery, Tim E. Moors, Marie-Alexandre Adom, Wolf N. Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J. Selkoe
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/39b56a097da94758adbfa5ee94a878bb
Autor:
Silke Nuber, Chee Yeun Chung, Daniel F. Tardiff, Pascal A. Bechade, Thomas D. McCaffery, Kazuma Shimanaka, Jeonghoon Choi, Belle Chang, Waseem Raja, Esther Neves, Christopher Burke, Xin Jiang, Ping Xu, Vikram Khurana, Ulf Dettmer, Saranna Fanning, Kenneth J. Rhodes, Dennis J. Selkoe, Robert H. Scannevin
Publikováno v:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 19(3)
Increasing evidence has shown that Parkinson’s disease (PD) impairs midbrain dopaminergic, cortical and other neuronal subtypes in large part due to the build-up of lipid- and vesicle-rich α-synuclein (αSyn) cytotoxic inclusions. We previously id
Autor:
Thomas D McCaffery, Silke Nuber, Warren D. Hirst, Alice Y Nam, Tim Moors, Dennis J. Selkoe, Andreas Weihofen, Kelly E. Glajch, Yi Chen, Ulf Dettmer, Molly M Rajsombath, Pascal A Bechade
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The mechanisms responsible for brain α-synuclein (αS) dyshomeostasis, caused by Gaucher’s GBA1 mutations that increase Parkinson’s disease (PD) risk, are largely unknown. We previously showed that abrogating physiological αS tetra
Publikováno v:
Pediatrics. 45:386-393
From a group of 130 youngsters with inflammatory bowel disease, 22 were severely growth retarded (below the third percentile in height). This had preceded gastrointestinal symptoms for 1 to 11.4 years in 8 patients and corticosteroid therapy in 14. E
Publikováno v:
The American journal of digestive diseases. 19(5)
In a previous study of 22 severely growth-retarded children with inflammatory bowel disease (IBD), endocrinologic evaluation revealed hypogonadism and low growth hormone (HGH) levels. This was attributed to a secondary hypopituitarism. In order to as
Autor:
Thomas D. McCaffery, James O. Lilly
Publikováno v:
The American journal of digestive diseases. 16(12)
A rapid, safe method of dilating tight esophageal strictures utilizing the Eder-Puestow dilators and the fiberoptic esophagoscope is described.
Autor:
Thomas D. McCaffery
Publikováno v:
Gastrointestinal Endoscopy. 21:167-168
nary parenchyma or in the walls of the blood vessels. These findings, especially the plasmacytoid lymphocytes, are consistent with the pathologic diagnosis of Waldenstrom's macroglobu Iinem ia.' Shortly after the lung biopsy, the patient's hematocrit
Autor:
THOMAS D. McCAFFERY
Publikováno v:
Southern Medical Journal. 72:256-257