Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Thomas D. James"'
Autor:
Samantha R. Pierson, Louis J. Kolling, Thomas D. James, Selvakumar Govindhasamy Pushpavathi, Catherine A. Marcinkiewcz
Publikováno v:
Pharmacological Research, Vol 203, Iss , Pp 107171- (2024)
The impact of Alzheimer’s disease (AD) and its related dementias is rapidly expanding, and its mitigation remains an urgent social and technical challenge. To date there are no effective treatments or interventions for AD, but recent studies sugges
Externí odkaz:
https://doaj.org/article/55096339b450405ab98a7e8785cfe538
Publikováno v:
eLife, Vol 8 (2019)
Synapses and circuits rely on neuroplasticity to adjust output and meet physiological needs. Forms of homeostatic synaptic plasticity impart stability at synapses by countering destabilizing perturbations. The Drosophila melanogaster larval neuromusc
Externí odkaz:
https://doaj.org/article/4f9549e113b54a0385f95ecd90f03291
Autor:
Douglas J Brusich, Ashlyn M Spring, Thomas D James, Catherine J Yeates, Timothy H Helms, C Andrew Frank
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://doaj.org/article/8e84afdcc7674cc9a7d61507fc3ce816
Autor:
Nagalakshmi Balasubramanian, Thomas D. James, Govindhasamy Pushpavathi Selvakumar, Jessica Reinhardt, Catherine A. Marcinkiewcz
Publikováno v:
Alcoholism, clinical and experimental research.
People with alcohol use disorders (AUD) may be at higher risk for COVID-19. Angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) are required for cellular entry of SARS-CoV-2, but information on their expression in spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab998988971ce830322de4f4d5d5b49f
https://pubmed.ncbi.nlm.nih.gov/35378747
https://pubmed.ncbi.nlm.nih.gov/35378747
Autor:
Nagalakshmi Balasubramanian, Thomas D James, Selvakumar Govindhasamy Pushpavathi, Catherine A. Marcinkiewcz
Emerging evidence suggests that people with alcohol use disorders are at higher risk for SARS-CoV-2. SARS-CoV-2 engages angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) receptors for cellular entry. While ACE2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f10ed7dae0094191672f245de7461da
https://doi.org/10.1101/2022.03.29.486282
https://doi.org/10.1101/2022.03.29.486282
Publikováno v:
Synapse (New York, N.y.)
The ability to adapt to changing internal and external conditions is a key feature of biological systems. Homeostasis refers to a regulatory process that stabilizes dynamic systems to counteract perturbations. In the nervous system, homeostatic mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b4097bfec07a6d9059f8bb8cfdf84c
https://doi.org/10.1002/syn.22133
https://doi.org/10.1002/syn.22133
Publikováno v:
eLife, Vol 8 (2019)
Synapses and circuits rely on neuroplasticity to adjust output and meet physiological needs. Forms of homeostatic synaptic plasticity impart stability at synapses by countering destabilizing perturbations. The Drosophila melanogaster larval neuromusc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e847eed796ef2234763500f2bf76377
https://doi.org/10.1101/356436
https://doi.org/10.1101/356436
Autor:
Douglas J Brusich, Thomas D. James, Ashlyn M. Spring, Timothy H. Helms, C. Andrew Frank, Catherine J. Yeates
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa289e63554deee5d9ba76c598891a6
https://doi.org/10.1101/141366
https://doi.org/10.1101/141366
Publikováno v:
Brain Research. 1516:55-65
Thyroid hormones induce short-latency nongenomic effects in adult brain tissue, suggesting that their acute administration would affect brain activity in intact animals. The influence on EEG-defined sleep of acute restoration of l-3,3'5-triiodothyron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070753b021a1bb5fb18d245cdbeb8221
https://doi.org/10.1016/j.brainres.2013.04.017
https://doi.org/10.1016/j.brainres.2013.04.017