Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Thomas D. Inch"'
Publikováno v:
Pure and Applied Chemistry. 74:2323-2352
This document was prepared as a report from IUPAC to the Organisation for the Prohibition of Chemical Weapons (OPCW) to provide an evaluation of scientific and technological advances in the chemical sciences relevant to the Chemical Weapons Conventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::057e2cf1271ded3021756599f9737447
https://doi.org/10.1351/pac200274122323
https://doi.org/10.1351/pac200274122323
Autor:
Thomas D. Inch
Publikováno v:
Ciba Foundation Symposium 57-Phosphorus in the Enviroment: Its Chemistry and Biochemistry
Organophosphorus anticholinesterase compounds may be derivatives of phosphoric acid or of a phosphonic acid. The phosphonic acid derivatives are usually more reactive and more toxic than the phosphoric acid derivatives. Examples are given to show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::540c4dd0e25b4cc46b74d8354258962c
https://doi.org/10.1002/9780470720387.ch8
https://doi.org/10.1002/9780470720387.ch8
Publikováno v:
Biochemical Journal. 155:1-4
6,7 -Dideoxy-α-D-gluco-heptose 7-phosphonic acid, the isosteric phosphonate analogue of glucose 6-phosphate, was synthesized in six steps from the readily available precursor benzyl 4,6-O-benzylidene-α-D-glucopyranoside. The analogue is a substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd7ba2909688ab1f7e6e56a3c6e6cad
https://doi.org/10.1042/bj1550001
https://doi.org/10.1042/bj1550001
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :639-643
1,3,2-Oxazaphospholidine-2-thiones derived from (+)-norephedrine react with alkoxide to give a product of kinetic control, formed by endocyclic P–O cleavage with inversion of configuration, and one of thermodynamic control, formed by endocyclic P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a67b309565ed9679338e4d51617b86a
https://doi.org/10.1039/p19820000639
https://doi.org/10.1039/p19820000639
Publikováno v:
Tetrahedron Letters. 20:5051-5054
Tetra-O-benzyl-α-D-glucopyranosyl bromide in dichloromethane reacts stereospecifically with solutions of phenols in aqueous sodium or potassium hydroxide, in the presence of phase transfer catalysts, to give good yields of tetra-O-benzyl aryl-β-D-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a184d031c8f9b15acbccf043f22bd008
https://doi.org/10.1016/s0040-4039(01)86787-3
https://doi.org/10.1016/s0040-4039(01)86787-3
Publikováno v:
Phosphorus and Sulfur and the Related Elements. 10:229-232
Added lithium cation has no effect on the stereochemical outcome of the displacement of chloride or p-nitrophenoxide from phosphorus in acyclic and some cyclic molecules. In other cyclic systems th...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abac964ba4a9542d7a3a0e829b18f527
https://doi.org/10.1080/03086648108077510
https://doi.org/10.1080/03086648108077510
Publikováno v:
Tetrahedron. 41:4909-4917
With R-(+) ethyl (or methyl) S-methyl methylphosphonothioate and (+)-pinacolyl alkoxide competitive and highly stereoselective displacements of O-alkyl and S-methyl occur, both reactions being with inversion of configuration. With the enantiomeric S-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb2e4ddbe4b2f7f7094fe70fc567e863
https://doi.org/10.1016/s0040-4020(01)96731-6
https://doi.org/10.1016/s0040-4020(01)96731-6
Autor:
C. Richard Hall, Thomas D. Inch
Publikováno v:
Tetrahedron. 36:2059-2095
The stereochemistry of endocyclic and exocyclic bond forming and breaking processes in 5- and 6-membered cyclic phosphorus esters is summarised and comparisons are made with analogous reactions in acyclic phosphorus esters. The factors that determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef7c066b9768c70539aa8a74062250f8
https://doi.org/10.1016/0040-4020(80)80096-2
https://doi.org/10.1016/0040-4020(80)80096-2
Publikováno v:
Tetrahedron Letters. 20:3557-3560
The reaction provides a new phosphonylation procedure for simple alcohols. Results obtained in inert solvents are consistent with the intermediacy of a phosphorus hemiacetal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6219632598864d76e91b3c3e8c79aba6
https://doi.org/10.1016/s0040-4039(01)95461-9
https://doi.org/10.1016/s0040-4039(01)95461-9
Autor:
D. G. Upshall, M. C. French, David J. Sellers, C. R. Hall, Thomas D. Inch, Andrew P. Smith, J. M. Harrison, P. Watts
Publikováno v:
Pesticide Biochemistry and Physiology. 24:53-60
R (+)-Ethyl S -propyl methylphosphonothioate is bioactivated both in vivo and when perfused through isolated liver to give a product which is much more active as an inhibitor of acetylcholinesterase than the parent compound. The bioactivation does no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e85a1cf7612a3525fc005d6cf0f8a036
https://doi.org/10.1016/0048-3575(85)90113-0
https://doi.org/10.1016/0048-3575(85)90113-0