Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Thomas D. Horvath"'
Autor:
Ian M. Lillie, Charles E. Booth, Adelaide E. Horvath, Matthew Mondragon, Melinda A. Engevik, Thomas D. Horvath
Publikováno v:
MicrobiologyOpen, Vol 13, Iss 2, Pp n/a-n/a (2024)
Abstract Arginine‐ornithine metabolism plays a crucial role in bacterial homeostasis, as evidenced by numerous studies. However, the utilization of arginine and the downstream products of its metabolism remain undefined in various gut bacteria. To
Externí odkaz:
https://doaj.org/article/1f793b047b40408cb65914123304a8c5
Autor:
Laura D. Hughes, Ginger Tsueng, Jack DiGiovanna, Thomas D. Horvath, Luke V. Rasmussen, Tor C. Savidge, Thomas Stoeger, Serdar Turkarslan, Qinglong Wu, Chunlei Wu, Andrew I. Su, Lars Pache, the NIAID Systems Biology Data Dissemination Working Group
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-7 (2023)
Externí odkaz:
https://doaj.org/article/c65ba8cb83f0451b9d283f3f55ebeb19
Autor:
Kristen A. Engevik, Hyland Gonzalez, Clay Daniels, Ronald K. Stavert, Numan Oezguen, Melinda A. Engevik, Thomas D. Horvath
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102540- (2023)
Summary: We present a protocol for measuring the pH of cell-free bacterial-conditioned media based on changes in the ultraviolet-visible (UV-Vis) absorbance spectrum using the pH indicator dye litmus. This protocol includes detailed procedures for pe
Externí odkaz:
https://doaj.org/article/022c00218f0149b0b5eab923e3139faa
Autor:
Thomas D. Horvath, Izmarie Poventud-Fuentes, Lily Olayinka, Asha James, Sigmund J. Haidacher, Kathleen M. Hoch, Alexandra M. Stevens, Anthony M. Haag, Sridevi Devaraj
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 26, Iss , Pp 23-27 (2022)
Background: Atovaquone has traditionally been used as an antiparasitic and antifungal agent, but recent studies have shown its potential as an anticancer agent. The high variability in atovaquone bioavailability highlights the need for therapeutic dr
Externí odkaz:
https://doaj.org/article/e11c3707c65349569aa0e0379c2e5d1d
Autor:
Melinda A. Engevik, Heather A. Danhof, Anne Hall, Kristen A. Engevik, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Bradley T. Endres, Meghna Bajaj, Kevin W. Garey, Robert A. Britton, Jennifer K. Spinler, Anthony M. Haag, James Versalovic
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-26 (2021)
Abstract Background Bifidobacteria are commensal microbes of the mammalian gastrointestinal tract. In this study, we aimed to identify the intestinal colonization mechanisms and key metabolic pathways implemented by Bifidobacterium dentium. Results B
Externí odkaz:
https://doaj.org/article/4b0f1ff8289a499390185793dc45b7e1
Autor:
Thomas D. Horvath, Faith D. Ihekweazu, Sigmund J. Haidacher, Wenly Ruan, Kristen A. Engevik, Robert Fultz, Kathleen M. Hoch, Ruth Ann Luna, Numan Oezguen, Jennifer K. Spinler, Anthony M. Haag, James Versalovic, Melinda A. Engevik
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104158- (2022)
Summary: Gut microbes can synthesize multiple neuro-active metabolites. We profiled neuro-active compounds produced by the gut commensal Bacteroides ovatus in vitro and in vivo by LC-MS/MS. We found that B. ovatus generates acetic acid, propionic aci
Externí odkaz:
https://doaj.org/article/9265eb55b5e3455eacfd6e2f6f4ffdf8
Autor:
Joao B. Xavier, Jonathan M. Monk, Saugat Poudel, Charles J. Norsigian, Anand V. Sastry, Chen Liao, Jose Bento, Marc A. Suchard, Mario L. Arrieta-Ortiz, Eliza J.R. Peterson, Nitin S. Baliga, Thomas Stoeger, Felicia Ruffin, Reese A.K. Richardson, Catherine A. Gao, Thomas D. Horvath, Anthony M. Haag, Qinglong Wu, Tor Savidge, Michael R. Yeaman
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104079- (2022)
Summary: Mathematical models have many applications in infectious diseases: epidemiologists use them to forecast outbreaks and design containment strategies; systems biologists use them to study complex processes sustaining pathogens, from the metabo
Externí odkaz:
https://doaj.org/article/1e825332653c49c0989978d4a000ec3b
Autor:
Melinda A. Engevik, Berkley Luck, Chonnikant Visuthranukul, Faith D. Ihekweazu, Amy C. Engevik, Zhongcheng Shi, Heather A. Danhof, Alexandra L. Chang-Graham, Anne Hall, Bradley T. Endres, Sigmund J. Haidacher, Thomas D. Horvath, Anthony M. Haag, Sridevi Devaraj, Kevin W. Garey, Robert A. Britton, Joseph M. Hyser, Noah F. Shroyer, James Versalovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 221-248 (2021)
Background & Aims: The human gut microbiota can regulate production of serotonin (5-hydroxytryptamine [5-HT]) from enterochromaffin cells. However, the mechanisms underlying microbial-induced serotonin signaling are not well understood. Methods: Adul
Externí odkaz:
https://doaj.org/article/104cb38cf9ef42919922904300f90cbe
Autor:
Robert Fultz, Taylor Ticer, Faith D. Ihekweazu, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Meghna Bajaj, Jennifer K. Spinler, Anthony M. Haag, Shelly A. Buffington, Melinda A. Engevik
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Background: Bacteroidetes are the most common bacterial phylum in the mammalian intestine and the effects of several Bacteroides spp. on multiple facets of host physiology have been previously described. Of the Bacteroides spp., Bacteroides ovatus ha
Externí odkaz:
https://doaj.org/article/3f81ecd7e8bc48e2bb3e0901f01bfe38
Autor:
Andrea C. Blackman, Santosh Thapa, Alamelu Venkatachalam, Thomas D. Horvath, Jessica K. Runge, Sigmund J. Haidacher, Kathleen M. Hoch, Anthony M. Haag, Ruth Ann Luna, Aikaterini Anagnostou
Publikováno v:
Children, Vol 9, Iss 8, p 1192 (2022)
Background: Peanut oral immunotherapy has emerged as a novel, active management approach for peanut-allergic sufferers, but limited data exist currently on the role of the microbiome in successful desensitization. Objective: We examined the oral and
Externí odkaz:
https://doaj.org/article/5cc622f0176e407280dfa3934dfe6efe