Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Thomas D Petes"'
Autor:
Lei Qi, Yang Sui, Xing-Xing Tang, Ryan J McGinty, Xiao-Zhuan Liang, Margaret Dominska, Ke Zhang, Sergei M Mirkin, Dao-Qiong Zheng, Thomas D Petes
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010590 (2023)
Although homologous recombination between transposable elements can drive genomic evolution in yeast by facilitating chromosomal rearrangements, the details of the underlying mechanisms are not fully clarified. In the genome of the yeast Saccharomyce
Externí odkaz:
https://doaj.org/article/e2c144da17f64f8f9a508562b585b3cc
Autor:
Hannah L. Klein, Giedrė Bačinskaja, Jun Che, Anais Cheblal, Rajula Elango, Anastasiya Epshtein, Devon M. Fitzgerald, Belén Gómez-González, Sharik R. Khan, Sandeep Kumar, Bryan A. Leland, Léa Marie, Qian Mei, Judith Miné-Hattab, Alicja Piotrowska, Erica J. Polleys, Christopher D. Putnam, Elina A. Radchenko, Anissia Ait Saada, Cynthia J. Sakofsky, Eun Yong Shim, Mathew Stracy, Jun Xia, Zhenxin Yan, Yi Yin, Andrés Aguilera, Juan Lucas Argueso, Catherine H. Freudenreich, Susan M. Gasser, Dmitry A. Gordenin, James E. Haber, Grzegorz Ira, Sue Jinks-Robertson, Megan C. King, Richard D. Kolodner, Andrei Kuzminov, Sarah AE Lambert, Sang Eun Lee, Kyle M. Miller, Sergei M. Mirkin, Thomas D. Petes, Susan M. Rosenberg, Rodney Rothstein, Lorraine S. Symington, Pawel Zawadzki, Nayun Kim, Michael Lisby, Anna Malkova
Publikováno v:
Microbial Cell, Vol 6, Iss 1, Pp 1-64 (2019)
Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily
Externí odkaz:
https://doaj.org/article/9deb4e4edc524ec78e599b9f614eaef3
Autor:
Yang Sui, Anastasiya Epstein, Margaret Dominska, Dao-Qiong Zheng, Thomas D Petes, Hannah L Klein
Publikováno v:
Nucleic Acids Research. 50:6890-6902
Ribonucleotides can be incorporated into DNA during replication by the replicative DNA polymerases. These aberrant DNA subunits are efficiently recognized and removed by Ribonucleotide Excision Repair, which is initiated by the heterotrimeric enzyme
Autor:
Sue Jinks-Robertson, Thomas D. Petes
Publikováno v:
Curr Opin Genet Dev
Saccharomyces cerevisiae is at the forefront of defining the major recombination mechanisms/models that repair targeted double-strand breaks during mitosis. Each of these models predicts specific molecular intermediates as well as genetic outcomes. R
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Although meiosis in warm-blooded organisms takes place in a narrow temperature range, meiosis in many organisms occurs over a wide variety of temperatures. We analyzed the properties of meiosis in the yeast Saccharomyces cerevisiae in cells
Externí odkaz:
https://doaj.org/article/7e1c619cb72f465ba061962abf471fc9
Autor:
Elena I. Stepchenkova, Piotr A. Mieczkowski, Thomas A. Kunkel, Adam B. Burkholder, Thomas D. Petes, Denis A. Kiktev, Peter M. J. Burgers, Margaret Dominska, Joseph Dahl, Scott A. Lujan, Tony Zhang
Publikováno v:
Nucleic Acids Research
Iron-sulfur clusters (4Fe–4S) exist in many enzymes concerned with DNA replication and repair. The contribution of these clusters to enzymatic activity is not fully understood. We identified the MET18 (MMS19) gene of Saccharomyces cerevisiae as a s
Publikováno v:
eLife, Vol 6 (2017)
In yeast, DNA breaks are usually repaired by homologous recombination (HR). An early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an intact DNA molecule. I
Externí odkaz:
https://doaj.org/article/441ded87ce644f0a8ef77f38d9e618c5
Autor:
Ke, Zhang, Yang, Sui, Wu-Long, Li, Gen, Chen, Xue-Chang, Wu, Robert J, Kokoska, Thomas D, Petes, Dao-Qiong, Zheng
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Although most studies of the genetic regulation of genome stability involve an analysis of mutations within the coding sequences of genes required for DNA replication or DNA repair, recent studies in yeast show that reduced levels of wil
Autor:
Sabrina L Andersen, Aimee Zhang, Margaret Dominska, María Moriel-Carretero, Emilia Herrera-Moyano, Andrés Aguilera, Thomas D Petes
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005938 (2016)
The Saccharomyces cerevisae RAD3 gene is the homolog of human XPD, an essential gene encoding a DNA helicase of the TFIIH complex involved in both nucleotide excision repair (NER) and transcription. Some mutant alleles of RAD3 (rad3-101 and rad3-102)
Externí odkaz:
https://doaj.org/article/4e34bf8082464838a446ffdf70d09c2b
Autor:
Yang Sui, Dao-Qiong Zheng, Thomas D. Petes, Robert J. Kokoska, Jian-Kun Wu, Xue-Ping Wen, Xing-Xing Tang, Zhong-Jun Ma, Ke Zhang, Lei Qi, Xuechang Wu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Although geneticists often emphasize diversity generated during sexual reproduction, genomic alterations that occur during vegetative growth are an important source of genetic diversity. In the current study, we have measured the rate an